ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR
fn fn fn fn fn
NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
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fn TESTBANK/COMPLETE GUIDE 2026-2027 ALL CHAPTERS 1-61
fn fn fn fn fn
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn
1. A patient diagnosed with obsessive–compulsive disorder has been prescribed
fn fn fn fn fn fn fn fn
oralparoxetine hydrochloride. What is the expected effect for this prescription?
fn fn fn fn fn fn fn fn fn fn fn
A. Curative effect on symptoms fn fn fn
B. Systemic effect on symptoms fn fn fn
C. Local effect on symptoms fn fn fn
D. Parenteral effect on symptoms fn fn fn
ACCURATE ANSWER:-B fn
REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into the fn fn fn fn fn fn fn fn fn
body, circulated through the bloodstream to their sites of action in various body tissues,
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
and eventually eliminated from the body. Curative agents are given to cure a disease
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
process. Inthis case, paroxetine hydrochloride will control the symptoms but not cure the
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
disorder.
fn
Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act mainly fn fn fn fn fn fn fn fn fn fn fn fn
at the site of application. Paroxetine hydrochloride is not administered parenterally.
fn fn fn fn fn fn fn fn fn fn fn
Parenteral agentsare administered subcutaneously, intramuscularly, or intravenously.
fn fn fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 3, Introduction OBJ: 1 fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Understand f nNOT: Multiple Choice fn fn f n fn
2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug is a
fn fn fn fn fn fn fn fn fn fn fn fn
naturally occurring substance that has been cheG
fn mRicAalDlyEm
fn
SoBdOifOieSd.TW
.C
haOt Mi s another fn fn fn fn fn fn fn fn fn fn
name for this type of pharmaceutical drug?
fn fn fn fn fn fn fn
A. Synthetic drug fn
B. Semisynthetic drug fn
C. Biotechnology drug fn
D. Prototype drug fn
ACCURATE ANSWER:-B fn
REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are fn fn fn fn fn fn
naturally occurring substances that have been chemically modified. Synthetic
fn fn fn fn fn fn fn fn fn
pharmaceutical drug are more standardized in their chemical characteristics, more
fn fn fn fn fn fn fn fn fn fn
consistent in their effects, and less likely to produce allergic reactions. Biotechnology
fn fn fn fn fn fn fn fn fn fn fn fn
pharmaceutical drug involve manipulating DNAand RNA and recombining genes into
fn fn fn fn fn fn fn fn fn fn fn
hybrid molecules that can be inserted into living organisms. Prototype pharmaceutical
fn fn fn fn fn fn fn fn fn fn fn
drug are the first drug of a particular group to be developed.
fn fn fn fn fn fn fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: 1 fn fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Understand f nNOT: Multiple Choice fn fn f n fn
3. Which classification applies to morphine?
fn fn fn fn
A. Central nervous system depressant fn fn fn
B. Central nervous system stimulant fn fn fn
, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A fn
REASONING:->>>Pharmaceutical drug are classified according to their effects on fn fn fn fn fn fn fn fn
particular body systems, their therapeutic uses, and their chemical characteristics.
fn fn fn fn fn fn fn fn fn fn
Morphine is classified as a central nervous system depressant and will produce this effect
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
in the hospital client. Acentral nervous system stimulant increases attention and raises
fn fn fn fn fn fn fn fn fn fn fn fn fn
mood. An anti-inflammatoryagent decreases inflammation at the site of tissue or joint
fn fn fn fn fn fn fn fn fn fn fn fn fn
inflammation. An antihypertensiveagent reduces blood pressure.
fn fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 3, Drug fn fn
Classifications and PrototypesOBJ:
fn 1 fn fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Remember f n NOT: Multiple Choice fn fn f n fn
4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical
fn fn fn fn fn fn fn fn fn fn fn
drug belongs to whichdrug group?
fn fn fn fn fn fn
A. Selective serotonin reuptake inhibitors fn fn fn
B. Diuretics
C. Penicillins
D. ACE inhibitors fn
ACCURATE ANSWER:-C fn
REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
GRADESBOOST.CO
with generic names ending in ―cillin‖ are penicillins). Selective serotonin
fn fn fn
fn
fn fn
fn
fn
fn
fn
fn fn
fn
fn fn
fn
fn fn fn
reuptakeinhibitors are pharmaceutical drugs
fn fn fn fn fn
that have antidepressant effects; SSRI is a broad classification, not a generic name.
fn fn fn fn fn fn fn fn fn fn fn fn
Diureticsare pharmaceutical drugs that increase urine output; diuretic is a broad
fn fn fn fn fn fn fn fn fn fn fn fn
classification, not a generic name. ACE inhibitor is the broad classification for the
fn fn fn fn fn fn fn fn fn fn fn fn fn
angiotensin receptor blockers, not thegeneric name.
fn fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: 2 fn fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Understand f n NOT: Multiple Choice fn fn f n fn
5. The administration of diphenhydramine is regulated by which U.S. government agency?
fn fn fn fn fn fn fn fn fn fn
A. Public Health Service fn fn
B. Federal Trade Commission fn fn
C. Occupational Safety and Health Administration fn fn fn fn
D. Food and fn
fn DrugAdministrati fn
on
ACCURATE ANSWER:-D fn
, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug for fn fn fn fn fn fn fn fn
over- the-counter availability, including the transfer of pharmaceutical drug from
fn fn fn fn fn fn fn fn fn fn
prescription to OTC status, and may require clinical trials to determine the safety and
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
effectiveness of OTC use.The Public Health Service is regulated by the state to maintain
fn fn fn fn fn fn fn fn fn fn fn fn fn fn fn
the health of individual citizens of the state. The Federal Trade Commission regulates
fn fn fn fn fn fn fn fn fn fn fn fn fn
imports and exports throughout the nation. The Occupational Safety and Health
fn fn fn fn fn fn fn fn fn fn fn
Administration regulates safetywithin the workplace.
fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription fn fn fn fn
Pharmaceutical drug OBJ: 4 fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Understandf n NOT: Multiple Choice fn fn f n fn
6. In the U.S., the administration of anabolic steroids is regulated by which law?
fn fn fn fn fn fn fn fn fn fn fn fn
A. The Food, Drug, and Cosmetic Act of 1938
fn fn fn fn fn fn fn
B. The Comprehensive Drug Abuse Prevention and Control Act
fn fn fn fn fn fn fn
C. The Harrison Narcotic Act fn fn fn
D. The Sherley Amendment fn fn
ACCURATE ANSWER:-B fn
REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act regulates fn fn fn fn fn fn fn fn
the manufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and
fn fn fn fn fn fn fn fn fn fn
anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
powers and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic
fn fn fn fn fn fn fn fn fn fn fn fn fn
Act restricted the importation, manufacture, sale, and use of opium,cocaine, marijuana, and
fn fn fn fn fn fn fn fn fn fn fn fn fn
other pharmaceutical drugthat the act d e fi Gn eRd AaDs E
fn fn naSrcBoO
tiO
csS
.TTh.eCSOhM
erley Amendment of1912 fn fn fn fn fn fn fn fn fn fn fn fn fn fn
prohibited fraudulent claims of drug effectiveness.
fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription fn fn fn fn
Pharmaceutical drug OBJ: 3 fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Remember f n NOT: Multiple Choice fn fn f n fn
7. A nursing attendant is responsible for maintaining an accurate count and record of the
fn fn fn fn fn fn fn fn fn fn fn fn fn
controlled substances on the nursing division. This nursing action is regulated by
fn fn fn fn fn fn fn fn fn fn fn fn
which
fn
U.S. law or agency?
fn fn fn
A. The Food, Drug, and Cosmetic Act of 1938
fn fn fn fn fn fn fn
B. The Public Health Service fn fn fn
C. The Drug Enforcement Administration
fn fn fn
D. The Sherley fn
AmendmentACCURATE
fn fn
fn ANSWER:-C
fn fn fn fn fn
NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
fn fn fn fn fn
fn TESTBANK/COMPLETE GUIDE 2026-2027 ALL CHAPTERS 1-61
fn fn fn fn fn
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn
1. A patient diagnosed with obsessive–compulsive disorder has been prescribed
fn fn fn fn fn fn fn fn
oralparoxetine hydrochloride. What is the expected effect for this prescription?
fn fn fn fn fn fn fn fn fn fn fn
A. Curative effect on symptoms fn fn fn
B. Systemic effect on symptoms fn fn fn
C. Local effect on symptoms fn fn fn
D. Parenteral effect on symptoms fn fn fn
ACCURATE ANSWER:-B fn
REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into the fn fn fn fn fn fn fn fn fn
body, circulated through the bloodstream to their sites of action in various body tissues,
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
and eventually eliminated from the body. Curative agents are given to cure a disease
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
process. Inthis case, paroxetine hydrochloride will control the symptoms but not cure the
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
disorder.
fn
Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act mainly fn fn fn fn fn fn fn fn fn fn fn fn
at the site of application. Paroxetine hydrochloride is not administered parenterally.
fn fn fn fn fn fn fn fn fn fn fn
Parenteral agentsare administered subcutaneously, intramuscularly, or intravenously.
fn fn fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 3, Introduction OBJ: 1 fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Understand f nNOT: Multiple Choice fn fn f n fn
2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug is a
fn fn fn fn fn fn fn fn fn fn fn fn
naturally occurring substance that has been cheG
fn mRicAalDlyEm
fn
SoBdOifOieSd.TW
.C
haOt Mi s another fn fn fn fn fn fn fn fn fn fn
name for this type of pharmaceutical drug?
fn fn fn fn fn fn fn
A. Synthetic drug fn
B. Semisynthetic drug fn
C. Biotechnology drug fn
D. Prototype drug fn
ACCURATE ANSWER:-B fn
REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are fn fn fn fn fn fn
naturally occurring substances that have been chemically modified. Synthetic
fn fn fn fn fn fn fn fn fn
pharmaceutical drug are more standardized in their chemical characteristics, more
fn fn fn fn fn fn fn fn fn fn
consistent in their effects, and less likely to produce allergic reactions. Biotechnology
fn fn fn fn fn fn fn fn fn fn fn fn
pharmaceutical drug involve manipulating DNAand RNA and recombining genes into
fn fn fn fn fn fn fn fn fn fn fn
hybrid molecules that can be inserted into living organisms. Prototype pharmaceutical
fn fn fn fn fn fn fn fn fn fn fn
drug are the first drug of a particular group to be developed.
fn fn fn fn fn fn fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: 1 fn fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Understand f nNOT: Multiple Choice fn fn f n fn
3. Which classification applies to morphine?
fn fn fn fn
A. Central nervous system depressant fn fn fn
B. Central nervous system stimulant fn fn fn
, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A fn
REASONING:->>>Pharmaceutical drug are classified according to their effects on fn fn fn fn fn fn fn fn
particular body systems, their therapeutic uses, and their chemical characteristics.
fn fn fn fn fn fn fn fn fn fn
Morphine is classified as a central nervous system depressant and will produce this effect
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
in the hospital client. Acentral nervous system stimulant increases attention and raises
fn fn fn fn fn fn fn fn fn fn fn fn fn
mood. An anti-inflammatoryagent decreases inflammation at the site of tissue or joint
fn fn fn fn fn fn fn fn fn fn fn fn fn
inflammation. An antihypertensiveagent reduces blood pressure.
fn fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 3, Drug fn fn
Classifications and PrototypesOBJ:
fn 1 fn fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Remember f n NOT: Multiple Choice fn fn f n fn
4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical
fn fn fn fn fn fn fn fn fn fn fn
drug belongs to whichdrug group?
fn fn fn fn fn fn
A. Selective serotonin reuptake inhibitors fn fn fn
B. Diuretics
C. Penicillins
D. ACE inhibitors fn
ACCURATE ANSWER:-C fn
REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
GRADESBOOST.CO
with generic names ending in ―cillin‖ are penicillins). Selective serotonin
fn fn fn
fn
fn fn
fn
fn
fn
fn
fn fn
fn
fn fn
fn
fn fn fn
reuptakeinhibitors are pharmaceutical drugs
fn fn fn fn fn
that have antidepressant effects; SSRI is a broad classification, not a generic name.
fn fn fn fn fn fn fn fn fn fn fn fn
Diureticsare pharmaceutical drugs that increase urine output; diuretic is a broad
fn fn fn fn fn fn fn fn fn fn fn fn
classification, not a generic name. ACE inhibitor is the broad classification for the
fn fn fn fn fn fn fn fn fn fn fn fn fn
angiotensin receptor blockers, not thegeneric name.
fn fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: 2 fn fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Understand f n NOT: Multiple Choice fn fn f n fn
5. The administration of diphenhydramine is regulated by which U.S. government agency?
fn fn fn fn fn fn fn fn fn fn
A. Public Health Service fn fn
B. Federal Trade Commission fn fn
C. Occupational Safety and Health Administration fn fn fn fn
D. Food and fn
fn DrugAdministrati fn
on
ACCURATE ANSWER:-D fn
, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug for fn fn fn fn fn fn fn fn
over- the-counter availability, including the transfer of pharmaceutical drug from
fn fn fn fn fn fn fn fn fn fn
prescription to OTC status, and may require clinical trials to determine the safety and
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
effectiveness of OTC use.The Public Health Service is regulated by the state to maintain
fn fn fn fn fn fn fn fn fn fn fn fn fn fn fn
the health of individual citizens of the state. The Federal Trade Commission regulates
fn fn fn fn fn fn fn fn fn fn fn fn fn
imports and exports throughout the nation. The Occupational Safety and Health
fn fn fn fn fn fn fn fn fn fn fn
Administration regulates safetywithin the workplace.
fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription fn fn fn fn
Pharmaceutical drug OBJ: 4 fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Understandf n NOT: Multiple Choice fn fn f n fn
6. In the U.S., the administration of anabolic steroids is regulated by which law?
fn fn fn fn fn fn fn fn fn fn fn fn
A. The Food, Drug, and Cosmetic Act of 1938
fn fn fn fn fn fn fn
B. The Comprehensive Drug Abuse Prevention and Control Act
fn fn fn fn fn fn fn
C. The Harrison Narcotic Act fn fn fn
D. The Sherley Amendment fn fn
ACCURATE ANSWER:-B fn
REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act regulates fn fn fn fn fn fn fn fn
the manufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and
fn fn fn fn fn fn fn fn fn fn
anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
fn fn fn fn fn fn fn fn fn fn fn fn fn fn
powers and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic
fn fn fn fn fn fn fn fn fn fn fn fn fn
Act restricted the importation, manufacture, sale, and use of opium,cocaine, marijuana, and
fn fn fn fn fn fn fn fn fn fn fn fn fn
other pharmaceutical drugthat the act d e fi Gn eRd AaDs E
fn fn naSrcBoO
tiO
csS
.TTh.eCSOhM
erley Amendment of1912 fn fn fn fn fn fn fn fn fn fn fn fn fn fn
prohibited fraudulent claims of drug effectiveness.
fn fn fn fn fn fn
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription fn fn fn fn
Pharmaceutical drug OBJ: 3 fn fn
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
fn fn fn fn fn fn fn fn
TherapiesTOP:
fn Chapter: 1: The Foundation of Pharmacology: Quality and Safety
fn fn fn fn fn fn fn fn fn
KEY: Integrated Process: Nursing Process
f n fn fn fn
BLM: Cognitive Level: Remember f n NOT: Multiple Choice fn fn f n fn
7. A nursing attendant is responsible for maintaining an accurate count and record of the
fn fn fn fn fn fn fn fn fn fn fn fn fn
controlled substances on the nursing division. This nursing action is regulated by
fn fn fn fn fn fn fn fn fn fn fn fn
which
fn
U.S. law or agency?
fn fn fn
A. The Food, Drug, and Cosmetic Act of 1938
fn fn fn fn fn fn fn
B. The Public Health Service fn fn fn
C. The Drug Enforcement Administration
fn fn fn
D. The Sherley fn
AmendmentACCURATE
fn fn
fn ANSWER:-C