NR293 Week 8 Class Activity

1. State idrugs iused iin ithe itreatment iof iThyroid iDisorders, ilist iside ieffects, iprecautions • Levothyroxine i(Synthroid, iLevoxyl) iSynthetic ithyroid ihormone iT4 iis ia ithyroid ireplacement idrug. iTREAT iHYPOTHYROIDISM iSide ieffects: iCardiac idysrhythmia iwith ilife- ithreatening iof ifatal iirregularities, iTachycardia, iPalpitation, iangina. iCNS: iInsomnia, itremors, iheadache, ianxiety. iGI: iNausea, iDiarrhea, icramps. iOther: iMenstrual iirregularities, iweight iloss, isweating, iheat iintolerance, ifever. iPrecautions: iDose iavailable iin imcg ivs img, idoses ihigher ithan i200 imcg ineed ito ibe iquestioned • Antithyroid iDrugs: iThionamides iderivatives, iPropylthiouracil, iMethimazole, iRadioactive iiodine i(iodine131), iPotassium iiodine. iTREAT iHYPERTHYROIDISM. iSide ieffects: ileukopenia i(fever, isore ithroat, ilesions) iPrecautions: iLiver iand ibone imarrow itoxicity, iuse iadvised ifor ipt iwith icardiac idisease ior ihypertension, iand ipregnant iwomen, iNever istop iabruptly, iavoid ieating ihigh iiodine ifoods i(seafood, isoy isauce, itofu, iand iiodized isalt.) 2. State idrugs iused iin ithe itreatment iof iType iI iand iType iII iDiabetes, ilist isymptoms iof ieach idisorder, iside ieffects iand iprecautions • Type i1 irequires iinsulin itherapy. iSymptoms: iHyperglycemia ipt irequire iexogenous iinsulin to ilower iblood iglucose ilevel. iSide ieffects: iglucose ilevel igiher ithan i126 img/dL, ipolyuria, ipolydipsia, ipolyphagia, iglucosuria, iweight iloss, iblurred ivision, iand ifatigue. iPrecautions: iMacrovascular i(atherosclerotic iplaque, iMicrovascular i( icapillary idamage) iRetinopathy- iblindness, idiabetic iulcers • Type i2 iNon ipharmacologic itreatment: iWeight iloss, iDietary ichange ihabits, ismoking cessation, iReduced ialcohol iconsumption, iRegular iexercise, isymptoms: ielevate iglucose ilevel, iSide ieffect: iglucose ilevel igreater ithan i126 img/dL, ipolyuria, ipolydipsia, ipolyphagia, iglucosuria, iweight iloss, iblurred ivision, iand ifatigue. iPrecautions: iconfusion, iirritability, itremors, isweating, ihypothermia, iseizures, icoma iand ideath iif inot itreated. 3. State idrugs iused iin ithe itreatment iof inausea iand ivomiting iassociated iwith icancer itreatment. iWhat iare ispecial iprecautions iand iside ieffects iof idrug itreatment? • Ondansetron i(Zofran) iured ito itreat inausea iand ichemotherapy iantiemetic. iPrecautions: igiven i30 ito i60 iminutes iprior ito ichemotherapy. • Serotonin iblockers: idelasetron, igranisetron, iondansetron, ipalonosetron iSide ieffects: iCNS: iheadache, iGI iDiarrhea, iOther: irash, ibronchospasm, iprolonged iQT iinterval. iPrecautions: igiven i30 ito i60 iminutes iprior ito ichemotherapy. • Megestrol iacetate i(megace) • Neurokinin iantagonist: iAprepitant, ifosaprepitant, irolapitant iSide ieffects: iCardiac: iHypotension, ibradycardia. iCNS iFatigue, idizziness. iGI: iDiarrhea, idyspepsia, iabdominal ipain, igastritis. iPrecautions: iinteracts iwith iwarfarin iand icontraceptives • Tatrahydrocannabinoids: idronabinol iSide ieffects: iCNS: iDrowsiness, idizziness, ianxiety, iconfusion, ieuphoria. iVisual idistubances, iGI: idry imouth Precautions iwith iknown idrug iallergy 4. State idrugs iused iin ithe itreatment iof iGERD, ihelicobacter ipylori? iWhat iis ithe iclassification? • H2 iReceptor iantagonists: iCimetidine, iRanitidine, iFamotidine iTreat iGERD • Proton iPump iInhibitor i(PPI) iLansoprazole, iOmeprazole, iRabeprazole, iPantoprazole, iEsomeprazole 5. What iare inursing iinterventions iif ia iclient iis isuspected iof ihaving iGI ibleeding irequiring ia iblood itransfusion? • Prepare itubing iand iIV ifor itransfusion • Only ihang iNormal isaline iwith iblood itransfusions • Check ivital isigns iprior ito ihanging iblood iassure ipatient idoes inot ihave ielevated itemperature • Hang iblood iwithin i15 ito i30 iminutes iof iobtaining ifrom iblood iblank • Monitor ivital isigns, irash, iitching, ielevated itemperature, isigns iof ianaphylactic ireaction, iStop itransfusion iif iany ireaction iand inotify iMD 6. State ia idrug iused iin ithe itreatment iof idementia? iSide ieffects, ispecial iprecautions? • Donepezil: iSide ieffects: iDizziness, iinsomnia, isomnolence, iheadache, ifatigue, iSeizures, idepression, iconfusion. iPrecautions: iPregnancy iCategory iC, ibreastfeeding, ichildren, isick isinus isyndrome, ihistory iof iulcers, iGI ibleeding, ihepatic idisease, ibladder iobstructions, ialthma, iseizures.