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, Psychopharmacology Fourth Edition !
Meyer • Quenzer C/ C/
Chapter 1: Principles of Pharmacology C/ C/ C/ C/
Multiple Choice C/
1. refer(s) to specific molecular changes that occur when a drug binds to a
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particular target site or receptor, while
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are the resulting widespread alterations in function.
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a. Drug action; therapeutic effects
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b. Side effects; drug effects
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c. Therapeutic effects; side effects C/ C/ C/
d. Drug action; drug effects
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Answer: d C/
Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is free t
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o bind at specific target sites is referred to as
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a. the therapeutic dose.
C/ C/
b. first-pass effects. C/
c. bioavailability.
d. ED50.
Answer: c C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target sit
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e or receptor are referred to as
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a. drug effects. C/
b. drug action. C/
c. side effects.C/
d. placebo effects. C/
Answer: b C/
Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning C/
b. Genetic variation C/
c. Drug competition C/
d. Expectation of outcome C/ C/
Answer: c C/
Textbook Reference: Pharmacology: The Science of Drug Action
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Page 2 of 247
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, 5. The administration of oxytocin has been proposed as a treatment for autism. C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administration
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b. Lipid solubility
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c. Depot binding C/
d. Drug action
C/
Answer: d C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken
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a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
C/ C/ is not complete.
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a. cerebrospinal fluid C/
b. blood–brain barrier C/
c. choroid plexus C/
d. phospholipid membrane C/
Answer: b C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
to general circulation.
C/ C/
c. drugs must first survive the acidic environment of the stomach.
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d. salivary enzymes in the mouth begin the process of metabolism.
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Answer: b C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. C/
b. choroid plexus. C/
c. area postrema.
C/
d. median eminence. C/
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Page 3 of 247
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Page 1 of 247
C/ C/ C/
, Psychopharmacology Fourth Edition !
Meyer • Quenzer C/ C/
Chapter 1: Principles of Pharmacology C/ C/ C/ C/
Multiple Choice C/
1. refer(s) to specific molecular changes that occur when a drug binds to a
C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
particular target site or receptor, while
C/ C/ C/ C/ C/
are the resulting widespread alterations in function.
C/ C/ C/ C/ C/ C/
a. Drug action; therapeutic effects
C/ C/ C/
b. Side effects; drug effects
C/ C/ C/
c. Therapeutic effects; side effects C/ C/ C/
d. Drug action; drug effects
C/ C/ C/
Answer: d C/
Textbook Reference: Pharmacology: The Science of Drug Action
C/ C/ C/ C/ C/ C/ C/
2. After drug administration has occurred, the amount of drug in the blood that is free t
C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
o bind at specific target sites is referred to as
C/ C/ C/ C/ C/ C/ C/ C/ C/
a. the therapeutic dose.
C/ C/
b. first-pass effects. C/
c. bioavailability.
d. ED50.
Answer: c C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
C/ C/ C/ C/ C/ C/
3. The specific molecular changes that occur when a drug binds to a particular target sit
C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
e or receptor are referred to as
C/ C/ C/ C/ C/ C/
a. drug effects. C/
b. drug action. C/
c. side effects.C/
d. placebo effects. C/
Answer: b C/
Textbook Reference: Pharmacology: The Science of Drug Action
C/ C/ C/ C/ C/ C/ C/
4. Which of the following is not a possible explanation for placebo effects?
C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
a. Pavlovian conditioning C/
b. Genetic variation C/
c. Drug competition C/
d. Expectation of outcome C/ C/
Answer: c C/
Textbook Reference: Pharmacology: The Science of Drug Action
C/ C/ C/ C/ C/ C/ C/
WWW.THENURSINGMASTERY.COM
Page 2 of 247
C/ C/ C/
, 5. The administration of oxytocin has been proposed as a treatment for autism. C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
C/ C/ C/ C/ C/ C/
6. Which factor does not affect the pharmacokinetics of a drug?
C/ C/ C/ C/ C/ C/ C/ C/ C/
a. Route of administration
C/ C/
b. Lipid solubility
C/
c. Depot binding C/
d. Drug action
C/
Answer: d C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
C/ C/ C/ C/ C/ C/
7. First-pass metabolism occurs when drugs are taken
C/ C/ C/ C/ C/ C/
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
C/ C/ C/ C/ C/ C/
8. The area postrema is one area in the brain where the
C/ C/ is not complete.
C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
a. cerebrospinal fluid C/
b. blood–brain barrier C/
c. choroid plexus C/
d. phospholipid membrane C/
Answer: b C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
C/ C/ C/ C/ C/ C/
9. First-pass metabolism occurs with orally administered drugs because
C/ C/ C/ C/ C/ C/ C/
a. their absorption is slowed by food.
C/ C/ C/ C/ C/
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
to general circulation.
C/ C/
c. drugs must first survive the acidic environment of the stomach.
C/ C/ C/ C/ C/ C/ C/ C/ C/
d. salivary enzymes in the mouth begin the process of metabolism.
C/ C/ C/ C/ C/ C/ C/ C/ C/
Answer: b C/
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
C/ C/ C/ C/ C/ C/
10. Toxic substances in the blood trigger a vomiting response by activating the
C/ C/ C/ C/ C/ C/ C/ C/ C/ C/ C/
a. blood–brain barrier. C/
b. choroid plexus. C/
c. area postrema.
C/
d. median eminence. C/
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Page 3 of 247
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