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Certification Prep Exam — Family Nurse Practitioner
Exam Year: 2025
Total Questions: 200 Multiple-Choice (A–D)
Sections: 8
Section 1: Advanced Health Assessment & Diagnostic Reasoning (Questions 1–25)
Section 2: Pharmacology & Pharmacotherapeutics for the FNP (Questions 26–50)
Section 3: Cardiovascular, Respiratory & Hematologic Conditions (Questions 51–75)
Section 4: Endocrine, Metabolic & Gastrointestinal Conditions (Questions 76–100)
Section 5: Women's Health, Prenatal & Reproductive Care (Questions 101–125)
Section 6: Pediatrics, Adolescents & Developmental Milestones (Questions 126–150)
Section 7: Mental Health, Neurology & Musculoskeletal Disorders (Questions 151–175)
Section 8: Health Promotion, Disease Prevention & Professional Practice (Questions
176–200)
Answers with rationales are provided beneath each question.
Aligned to the 2025 certification body of knowledge.
Page 1 of 74
,Table of Contents
Section 1: Advanced Health Assessment & Diagnostic Reasoning (Questions 1–25)3
Section 2: Pharmacology & Pharmacotherapeutics for the FNP (Questions 26–50)12
Section 3: Cardiovascular, Respiratory & Hematologic Conditions (Questions 51–75)21
Section 4: Endocrine, Metabolic & Gastrointestinal Conditions (Questions 76–100)30
Section 5: Women's Health, Prenatal & Reproductive Care (Questions 101–125)39
Section 6: Pediatrics, Adolescents & Developmental Milestones (Questions 126–150)48
Section 7: Mental Health, Neurology & Musculoskeletal Disorders (Questions 151–175)57
Section 8: Health Promotion, Disease Prevention & Professional Practice (Questions
176–200)66
Page 2 of 74
,Section 1: Advanced Health Assessment & Diagnostic Reasoning
(Questions 1–25)
Q1: A 68-year-old client has a harsh systolic murmur at the right upper sternal border that
radiates to the carotids and a diminished second heart sound. Which valve lesion is most
likely?
A. Aortic stenosis **[CORRECT]**
B. Mitral regurgitation
C. Aortic regurgitation
D. Mitral stenosis
Correct Answer: A
Rationale: A crescendo-decrescendo systolic murmur radiating to the carotids with a soft
S2 is characteristic of aortic stenosis. Mitral regurgitation radiates to the axilla, while aortic
regurgitation and mitral stenosis are diastolic murmurs.
Q2: A 34-year-old presents with sharp chest pain that worsens when lying flat and improves
when sitting forward, along with a friction rub. Which diagnosis is most likely?
A. Acute pericarditis **[CORRECT]**
B. Myocardial infarction
C. Aortic dissection
D. Pulmonary embolism
Correct Answer: A
Rationale: Positional sharp pain with a friction rub is classic for pericarditis; the pain is
pleuritic and relieved by sitting forward. Infarction pain is pressure-like, dissection is
tearing and sudden, and pulmonary embolism presents with dyspnea and tachycardia.
Q3: A 62-year-old with a 40 pack-year smoking history presents with a new, painless, hard,
fixed supraclavicular lymph node. What is the priority action?
A. Reassure the client that nodes are usually reactive
B. Prescribe a 10-day course of antibiotics and recheck in two weeks
C. Refer for urgent lymph node biopsy and malignancy evaluation **[CORRECT]**
D. Order a complete blood count and follow up in three months
Correct Answer: C
Rationale: A hard, fixed, painless supraclavicular node in a high-risk smoker suggests
malignancy such as lung cancer or lymphoma and requires urgent biopsy. Reassurance,
empiric antibiotics, and delayed follow-up risk diagnostic delay.
Page 3 of 74
, Q4: During otoscopy of a 70-year-old with hearing loss, which finding suggests otitis externa
rather than otitis media?
A. A retracted, intact tympanic membrane
B. An immobile tympanic membrane
C. Pain with movement of the auricle and a swollen, erythematous canal **[CORRECT]**
D. An amber-colored tympanic membrane with an air-fluid level
Correct Answer: C
Rationale: Canal edema with pain exacerbated by auricular manipulation is typical of otitis
externa. Retraction, decreased mobility, and an air-fluid level point to middle-ear
pathology.
Q5: A client reports right upper quadrant pain 30 minutes after eating fatty meals, and the
nurse practitioner elicits pain on abrupt cessation of deep palpation under the right costal
margin. Which sign is this, and what diagnosis does it suggest?
A. Murphy sign, suggesting acute cholecystitis **[CORRECT]**
B. McBurney sign, suggesting appendicitis
C. Rovsing sign, suggesting peritonitis
D. Blumberg sign, suggesting pancreatitis
Correct Answer: A
Rationale: Murphy sign is inspiratory arrest with right subcostal palpation, indicating
gallbladder inflammation. The other signs relate to appendicitis and peritoneal irritation in
different locations.
Q6: What is the correct order of abdominal examination techniques for a client with abdominal
pain?
A. Palpation, percussion, auscultation, inspection
B. Inspection, auscultation, percussion, palpation **[CORRECT]**
C. Auscultation, palpation, inspection, percussion
D. Percussion, inspection, palpation, auscultation
Correct Answer: B
Rationale: Auscultation precedes percussion and palpation because manipulating the
abdomen alters bowel sounds. Examining before percussion and palpation preserves the
reliability of auscultation.
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