, NURS 5334 MODULE 3 QUIZ
Advanced Pharmacology for Nurse Practitioners
University of Texas at Arlington (UTA) 100-
Question Original Practice Quiz
2026/2027 Edition
1. For a patient being treated with Hydrocortisone topical, the most appropriate primary use is:
A) purine antimetabolite immunosuppressant used in autoimmune disease and transplantation
B) low-potency topical corticosteroid for mild inflammatory dermatoses and sensitive areas
C) intravenous TNF inhibitor used for inflammatory conditions such as rheumatoid arthritis and
inflammatorybowel disease
D) first-line topical scabicide for classic scabies in many patients
Correct Answer: low-potency topical corticosteroid for mild inflammatory dermatoses and sensitive areas
Rationale: Hydrocortisone topical is appropriately used as low-potency topical corticosteroid for mild inflammatory
dermatoses and sensitive areas. The competing choices describe therapeutic roles of other dermatologic or
immunomodulatory agents and would not represent the principal reason to select this medication. Matching the drug to
its core indication helps prevent inappropriate therapy and supports safer prescribing decisions.
2. Before initiating Hydrocortisone topical, which safety concern deserves the greatest attention?
A) local burning, irritation, or dryness
B) skin atrophy and telangiectasia with excessive or prolonged use
C) local skin atrophy and hypothalamic-pituitary-adrenal suppression if used extensively
D) local itching or irritation; post-scabetic pruritus may persist despite successful treatment
Correct Answer: skin atrophy and telangiectasia with excessive or prolonged use
Rationale: A major safety issue with Hydrocortisone topical is skin atrophy and telangiectasia with excessive or
prolonged use. This risk should be considered before and during therapy because it may change patient selection,
dosing, counseling, or follow-up. The alternative adverse-effect profiles belong more strongly to other agents and would
misdirect monitoring priorities.
3. Follow-up for a patient receiving Hydrocortisone topical should emphasize:
A) duration, treated body-surface area, and evidence of local adverse effects
B) CBC, liver tests, and consideration of TPMT/NUDT15 activity where appropriate
C) treatment response, skin integrity, and extent/duration of use
D) clinical response and signs of local skin thinning
Correct Answer: clinical response and signs of local skin thinning
Rationale: For Hydrocortisone topical, appropriate follow-up includes clinical response and signs of local skin thinning.
Monitoring should be targeted to predictable toxicities, treatment response, and patient-specific risk rather than using the
same tests for every medication. The other choices correspond to monitoring needs of different drugs and are less
relevant to this agent.
4. Patient education for Hydrocortisone topical should include which instruction?
A) warn that it can bleach hair and colored fabrics
B) hold and seek clinical advice for significant infection or fever
C) take with a full glass of water and remain upright after dosing
NURS 5334 Module 3 Quiz | Practice Assessment | 2026/2027 Edition | Page 1
, D) apply a thin layer and use the lowest effective potency for the shortest practical duration
Correct Answer: apply a thin layer and use the lowest effective potency for the shortest practical duration
Rationale: Safe use of Hydrocortisone topical includes the instruction to apply a thin layer and use the lowest effective
potency for the shortest practical duration. This counseling point directly addresses a preventable adverse outcome,
adherence issue, or administration problem. The other statements may be appropriate for different medications but do
not represent the most important practical teaching point for this therapy.
5. In advanced-practice prescribing, Triamcinolone topical is best matched with which indication?
A) TNF inhibitor used for rheumatoid arthritis and plaque psoriasis
B) topical antibiotic used for inflammatory acne, usually with benzoyl peroxide
C) medium-potency topical corticosteroid for inflammatory dermatoses on trunk or extremities
D) low-potency topical corticosteroid for mild inflammatory dermatoses and sensitive areas
Correct Answer: medium-potency topical corticosteroid for inflammatory dermatoses on trunk or
extremities
Rationale: Triamcinolone topical is appropriately used as medium-potency topical corticosteroid for inflammatory
dermatoses on trunk or extremities. The competing choices describe therapeutic roles of other dermatologic or
immunomodulatory agents and would not represent the principal reason to select this medication. Matching the drug to
its core indication helps prevent inappropriate therapy and supports safer prescribing decisions.
6. The key toxicity associated with Triamcinolone topical is:
A) skin atrophy and telangiectasia with excessive or prolonged use
B) bone-marrow suppression, hepatotoxicity, infection, and interaction with xanthine oxidase inhibitorsC)
irritation, photosensitivity, and peeling
D) local skin atrophy and hypothalamic-pituitary-adrenal suppression if used extensively
Correct Answer: local skin atrophy and hypothalamic-pituitary-adrenal suppression if used extensively
Rationale: A major safety issue with Triamcinolone topical is local skin atrophy and hypothalamic-pituitary-adrenal
suppression if used extensively. This risk should be considered before and during therapy because it may change
patient selection, dosing, counseling, or follow-up. The alternative adverse-effect profiles belong more strongly to other
agents and would misdirect monitoring priorities.
7. What monitoring plan is most appropriate for Triamcinolone topical? A)
duration, treated body-surface area, and evidence of local adverse effects
B) tolerability and improvement in inflammatory lesions
C) treatment response, skin integrity, and extent/duration of use
D) response, adverse effects, and need for continued systemic antibiotic therapy
Correct Answer: treatment response, skin integrity, and extent/duration of use
Rationale: For Triamcinolone topical, appropriate follow-up includes treatment response, skin integrity, and
extent/duration of use. Monitoring should be targeted to predictable toxicities, treatment response, and patient-specific
risk rather than using the same tests for every medication. The other choices correspond to monitoring needs of different
drugs and are less relevant to this agent.
8. Which counseling statement is most appropriate for Triamcinolone topical?
A) strictly avoid pregnancy and follow the required risk-management program
B) review individual risks carefully and report signs of clotting or serious infection promptly
C) avoid routine use on the face, groin, and intertriginous areas unless specifically directed
NURS 5334 Module 3 Quiz | Practice Assessment | 2026/2027 Edition | Page 2
Advanced Pharmacology for Nurse Practitioners
University of Texas at Arlington (UTA) 100-
Question Original Practice Quiz
2026/2027 Edition
1. For a patient being treated with Hydrocortisone topical, the most appropriate primary use is:
A) purine antimetabolite immunosuppressant used in autoimmune disease and transplantation
B) low-potency topical corticosteroid for mild inflammatory dermatoses and sensitive areas
C) intravenous TNF inhibitor used for inflammatory conditions such as rheumatoid arthritis and
inflammatorybowel disease
D) first-line topical scabicide for classic scabies in many patients
Correct Answer: low-potency topical corticosteroid for mild inflammatory dermatoses and sensitive areas
Rationale: Hydrocortisone topical is appropriately used as low-potency topical corticosteroid for mild inflammatory
dermatoses and sensitive areas. The competing choices describe therapeutic roles of other dermatologic or
immunomodulatory agents and would not represent the principal reason to select this medication. Matching the drug to
its core indication helps prevent inappropriate therapy and supports safer prescribing decisions.
2. Before initiating Hydrocortisone topical, which safety concern deserves the greatest attention?
A) local burning, irritation, or dryness
B) skin atrophy and telangiectasia with excessive or prolonged use
C) local skin atrophy and hypothalamic-pituitary-adrenal suppression if used extensively
D) local itching or irritation; post-scabetic pruritus may persist despite successful treatment
Correct Answer: skin atrophy and telangiectasia with excessive or prolonged use
Rationale: A major safety issue with Hydrocortisone topical is skin atrophy and telangiectasia with excessive or
prolonged use. This risk should be considered before and during therapy because it may change patient selection,
dosing, counseling, or follow-up. The alternative adverse-effect profiles belong more strongly to other agents and would
misdirect monitoring priorities.
3. Follow-up for a patient receiving Hydrocortisone topical should emphasize:
A) duration, treated body-surface area, and evidence of local adverse effects
B) CBC, liver tests, and consideration of TPMT/NUDT15 activity where appropriate
C) treatment response, skin integrity, and extent/duration of use
D) clinical response and signs of local skin thinning
Correct Answer: clinical response and signs of local skin thinning
Rationale: For Hydrocortisone topical, appropriate follow-up includes clinical response and signs of local skin thinning.
Monitoring should be targeted to predictable toxicities, treatment response, and patient-specific risk rather than using the
same tests for every medication. The other choices correspond to monitoring needs of different drugs and are less
relevant to this agent.
4. Patient education for Hydrocortisone topical should include which instruction?
A) warn that it can bleach hair and colored fabrics
B) hold and seek clinical advice for significant infection or fever
C) take with a full glass of water and remain upright after dosing
NURS 5334 Module 3 Quiz | Practice Assessment | 2026/2027 Edition | Page 1
, D) apply a thin layer and use the lowest effective potency for the shortest practical duration
Correct Answer: apply a thin layer and use the lowest effective potency for the shortest practical duration
Rationale: Safe use of Hydrocortisone topical includes the instruction to apply a thin layer and use the lowest effective
potency for the shortest practical duration. This counseling point directly addresses a preventable adverse outcome,
adherence issue, or administration problem. The other statements may be appropriate for different medications but do
not represent the most important practical teaching point for this therapy.
5. In advanced-practice prescribing, Triamcinolone topical is best matched with which indication?
A) TNF inhibitor used for rheumatoid arthritis and plaque psoriasis
B) topical antibiotic used for inflammatory acne, usually with benzoyl peroxide
C) medium-potency topical corticosteroid for inflammatory dermatoses on trunk or extremities
D) low-potency topical corticosteroid for mild inflammatory dermatoses and sensitive areas
Correct Answer: medium-potency topical corticosteroid for inflammatory dermatoses on trunk or
extremities
Rationale: Triamcinolone topical is appropriately used as medium-potency topical corticosteroid for inflammatory
dermatoses on trunk or extremities. The competing choices describe therapeutic roles of other dermatologic or
immunomodulatory agents and would not represent the principal reason to select this medication. Matching the drug to
its core indication helps prevent inappropriate therapy and supports safer prescribing decisions.
6. The key toxicity associated with Triamcinolone topical is:
A) skin atrophy and telangiectasia with excessive or prolonged use
B) bone-marrow suppression, hepatotoxicity, infection, and interaction with xanthine oxidase inhibitorsC)
irritation, photosensitivity, and peeling
D) local skin atrophy and hypothalamic-pituitary-adrenal suppression if used extensively
Correct Answer: local skin atrophy and hypothalamic-pituitary-adrenal suppression if used extensively
Rationale: A major safety issue with Triamcinolone topical is local skin atrophy and hypothalamic-pituitary-adrenal
suppression if used extensively. This risk should be considered before and during therapy because it may change
patient selection, dosing, counseling, or follow-up. The alternative adverse-effect profiles belong more strongly to other
agents and would misdirect monitoring priorities.
7. What monitoring plan is most appropriate for Triamcinolone topical? A)
duration, treated body-surface area, and evidence of local adverse effects
B) tolerability and improvement in inflammatory lesions
C) treatment response, skin integrity, and extent/duration of use
D) response, adverse effects, and need for continued systemic antibiotic therapy
Correct Answer: treatment response, skin integrity, and extent/duration of use
Rationale: For Triamcinolone topical, appropriate follow-up includes treatment response, skin integrity, and
extent/duration of use. Monitoring should be targeted to predictable toxicities, treatment response, and patient-specific
risk rather than using the same tests for every medication. The other choices correspond to monitoring needs of different
drugs and are less relevant to this agent.
8. Which counseling statement is most appropriate for Triamcinolone topical?
A) strictly avoid pregnancy and follow the required risk-management program
B) review individual risks carefully and report signs of clotting or serious infection promptly
C) avoid routine use on the face, groin, and intertriginous areas unless specifically directed
NURS 5334 Module 3 Quiz | Practice Assessment | 2026/2027 Edition | Page 2
