ABO PROFESSIONAL OPTICIAN PREP Questions with Correct
Answers (Grade A+)
Question 1: The major immunoglobulin classes of anti-B in a group A individual is (are)
A. IgM
B. IgG
C. IgM and IgG
D. IgM and IgA
Answer: A
Question 2: What are the possible ABO phenotypes of the offspring from the mating of a group A to a
group B Individual?
A. O, A, B
B. A, B
C. A, B, AB
D. O, A, B, AB
Answer: D
Question 3: The immunodominant sugar responsible for blood group A specificity is:
A. L-fructose
B. N-acetyl-D-galactosamine
C. D-galactose
D. Uridine diphosphate-N-acetyl-D-galactose
Answer: B
Question 4: What ABH substances should be found in the saliva of a group B secretor?
A. H
B. H and A
C. H and B
D. H, A, and B
Answer: C
Question 5: An ABO type on a patient gives the following reactions: -Patient cells with: Anti-A- 4+,
Anti-B- 4+, Anti-A1- neg -Patient serum with: A1 cells- 2+, B cells- Neg The reactions above may be
seen in a patient who is
A. A1 with acquired B
B. A2B with anti-A1
C. AB with increased concentrations of protein in the serum
D. AB with an autoantibody
Answer: B
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,Question 6: Which of the following ABO Blood groups contains the least amount of H substance?
A. A1B
B. A2
C. B
D. O
Answer: A
Question 7: You are working on a specimen in the lab that you believe to be a Bombay phenotype.
Which of the following reactions would you expect to see?
A. Patients cells + Ulex europaeus= no agglutination
B. Patients cells + Ulex europaeus= agglutination
C. Patients serum + group O donor RBCs= no agglutination
D. Patients serum + A1 and B cels= no agglutination
Answer: A
Question 8: An example of a technical error that can result in an ABO discrepancy is
A. Acquired B phenomenon
B. Mising isoagglutinins
C. Cell suspension that is too heavy
D. Acriflavine antibodies
Answer: C
Question 9: An ABO type on a patient gives the following reactions: Patient cells with: Anti-A- 4+,
Anti-B- neg Patient serum with: A1 cells- 2+, B cells-4+, O cells-2+, Autocontrol- Neg These results are
most likely due to:
A. ABO alloantibody
B. Non-ABO alloantibody
C. Rouleaux
D. Cold autoantibody
Answer: B
Question 10: Regarding the frequency of ABO blood groups -Group O
A. 45%
B. 40%
C. 11%
D. 4%
Answer: A
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, Question 11: Regarding the frequency of ABO blood groups -Group A
A. 45%
B. 40%
C. 11%
D. 4%
Answer: B
Question 12: Regarding the frequency of ABO blood groups -Group B
A. 45%
B. 40%
C. 11%
D. 4%
Answer: C
Question 13: Regarding the frequency of ABO blood groups -Group AB
A. 45%
B. 40%
C. 11%
D. 4%
Answer: D
Question 14: The ABO blood group system has naturally occuring antibodies that are primarily ______
Answer: IgM
Question 15: ABO genes, like those of other blood groups are inherited in a _____________-manner
Answer: codominant
Question 16: ABH_______________ are secreted by tissue cells and are found in all body secretions.
The antigens secreted depend on the persons ABO group
Answer: soluble antigens
Question 17: ABO _______grouping is omitted from cord blood testing on newborns because their
antibody titer levels are generally too low for detection
Answer: reverse
Question 18: ABO RBC ________can be glycolipids, glycoproteins or glycosphingolipid;
Answer: antigens
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Answers (Grade A+)
Question 1: The major immunoglobulin classes of anti-B in a group A individual is (are)
A. IgM
B. IgG
C. IgM and IgG
D. IgM and IgA
Answer: A
Question 2: What are the possible ABO phenotypes of the offspring from the mating of a group A to a
group B Individual?
A. O, A, B
B. A, B
C. A, B, AB
D. O, A, B, AB
Answer: D
Question 3: The immunodominant sugar responsible for blood group A specificity is:
A. L-fructose
B. N-acetyl-D-galactosamine
C. D-galactose
D. Uridine diphosphate-N-acetyl-D-galactose
Answer: B
Question 4: What ABH substances should be found in the saliva of a group B secretor?
A. H
B. H and A
C. H and B
D. H, A, and B
Answer: C
Question 5: An ABO type on a patient gives the following reactions: -Patient cells with: Anti-A- 4+,
Anti-B- 4+, Anti-A1- neg -Patient serum with: A1 cells- 2+, B cells- Neg The reactions above may be
seen in a patient who is
A. A1 with acquired B
B. A2B with anti-A1
C. AB with increased concentrations of protein in the serum
D. AB with an autoantibody
Answer: B
Page 1
,Question 6: Which of the following ABO Blood groups contains the least amount of H substance?
A. A1B
B. A2
C. B
D. O
Answer: A
Question 7: You are working on a specimen in the lab that you believe to be a Bombay phenotype.
Which of the following reactions would you expect to see?
A. Patients cells + Ulex europaeus= no agglutination
B. Patients cells + Ulex europaeus= agglutination
C. Patients serum + group O donor RBCs= no agglutination
D. Patients serum + A1 and B cels= no agglutination
Answer: A
Question 8: An example of a technical error that can result in an ABO discrepancy is
A. Acquired B phenomenon
B. Mising isoagglutinins
C. Cell suspension that is too heavy
D. Acriflavine antibodies
Answer: C
Question 9: An ABO type on a patient gives the following reactions: Patient cells with: Anti-A- 4+,
Anti-B- neg Patient serum with: A1 cells- 2+, B cells-4+, O cells-2+, Autocontrol- Neg These results are
most likely due to:
A. ABO alloantibody
B. Non-ABO alloantibody
C. Rouleaux
D. Cold autoantibody
Answer: B
Question 10: Regarding the frequency of ABO blood groups -Group O
A. 45%
B. 40%
C. 11%
D. 4%
Answer: A
Page 2
, Question 11: Regarding the frequency of ABO blood groups -Group A
A. 45%
B. 40%
C. 11%
D. 4%
Answer: B
Question 12: Regarding the frequency of ABO blood groups -Group B
A. 45%
B. 40%
C. 11%
D. 4%
Answer: C
Question 13: Regarding the frequency of ABO blood groups -Group AB
A. 45%
B. 40%
C. 11%
D. 4%
Answer: D
Question 14: The ABO blood group system has naturally occuring antibodies that are primarily ______
Answer: IgM
Question 15: ABO genes, like those of other blood groups are inherited in a _____________-manner
Answer: codominant
Question 16: ABH_______________ are secreted by tissue cells and are found in all body secretions.
The antigens secreted depend on the persons ABO group
Answer: soluble antigens
Question 17: ABO _______grouping is omitted from cord blood testing on newborns because their
antibody titer levels are generally too low for detection
Answer: reverse
Question 18: ABO RBC ________can be glycolipids, glycoproteins or glycosphingolipid;
Answer: antigens
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