ABO ADVANCED FORMULAS TEST PAPER Questions with
Correct Answers (Grade A+)
Question 1: What immunoglobulin class is primarily associated with ABO antibodies?
Answer: IgM
Question 2: What immunodominant sugar confers B blood group specificity?
Answer: D-galactose
Question 3: An individual has the genotype of AO, hh. What antigens would be present on the red cells
of this individual?
Answer: A only
Question 4: What gene controls the presence of soluble H substance in saliva?
Answer: Se
Question 5: Which lectin agglutinates A₁ red cells?
Answer: Dolichos biflorus
Question 6: What immunodominant sugar determines the specificity of H antigens?
Answer: L-fucose
Question 7: Which of the following situations may produce ABO discrepancies in the serum testing?
Answer: All the above (newborn, patient with hypogammaglobulinemia, cold alloantibody)
Question 8: What soluble antigen forms are detectable in saliva based on the following genotype: AB,
HH, SeSe?
Answer: A, B, and H
Question 9: What ABO phenotypes would be compatible if the patient required a transfusion of RBCs?
Anti-a neg, anti-b neg, a1 is 4+, b is 4+
Answer: Group O or B
Question 10: What ABO phenotypes would be compatible if the patient required a transfusion of fresh
frozen plasma? Anti-a neg, anti-b neg, a1 is 4+, b is 4+
Answer: Group AB, O, A, or B
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Correct Answers (Grade A+)
Question 1: What immunoglobulin class is primarily associated with ABO antibodies?
Answer: IgM
Question 2: What immunodominant sugar confers B blood group specificity?
Answer: D-galactose
Question 3: An individual has the genotype of AO, hh. What antigens would be present on the red cells
of this individual?
Answer: A only
Question 4: What gene controls the presence of soluble H substance in saliva?
Answer: Se
Question 5: Which lectin agglutinates A₁ red cells?
Answer: Dolichos biflorus
Question 6: What immunodominant sugar determines the specificity of H antigens?
Answer: L-fucose
Question 7: Which of the following situations may produce ABO discrepancies in the serum testing?
Answer: All the above (newborn, patient with hypogammaglobulinemia, cold alloantibody)
Question 8: What soluble antigen forms are detectable in saliva based on the following genotype: AB,
HH, SeSe?
Answer: A, B, and H
Question 9: What ABO phenotypes would be compatible if the patient required a transfusion of RBCs?
Anti-a neg, anti-b neg, a1 is 4+, b is 4+
Answer: Group O or B
Question 10: What ABO phenotypes would be compatible if the patient required a transfusion of fresh
frozen plasma? Anti-a neg, anti-b neg, a1 is 4+, b is 4+
Answer: Group AB, O, A, or B
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