NCLEX RN Pharmacological and
Parenteral Therapies Exam 3 100
Questions And Correct Answers
(Verified Answers) Plus Rationales
2026 Q&A Instant Download Pdf
1. A client receiving digoxin reports nausea, anorexia, and seeing yellow-
green halos around lights. Which action should the nurse take first?
A. Administer the scheduled dose with food
B. Hold the digoxin and notify the provider
C. Encourage increased fluid intake
D. Administer an antacid
Answer: B. Hold the digoxin and notify the provider
Rationale: These findings are consistent with digoxin toxicity. The nurse
should withhold the medication and notify the provider.
2. Which assessment finding is most important for a client receiving
furosemide?
A. Increased appetite
B. Warm, flushed skin
C. Serum potassium of 2.8 mEq/L
D. Blood glucose of 110 mg/dL
Answer: C. Serum potassium of 2.8 mEq/L
Rationale: Furosemide can cause significant potassium loss. Severe
hypokalemia increases the risk of dysrhythmias and requires prompt
intervention.
, 3. A client prescribed warfarin asks which food should be consumed
consistently rather than avoided completely. Which food is appropriate?
A. Grapefruit
B. Spinach
C. Bananas
D. Milk
Answer: B. Spinach
Rationale: Spinach contains vitamin K, which can decrease warfarin's
anticoagulant effect. Clients should maintain a consistent intake of vitamin K
rather than abruptly changing consumption.
4. Which medication reverses the effects of heparin?
A. Vitamin K
B. Acetylcysteine
C. Naloxone
D. Protamine sulfate
Answer: D. Protamine sulfate
Rationale: Protamine sulfate is the antidote for unfractionated heparin.
Vitamin K is used to reverse warfarin.
5. A client receiving IV morphine becomes difficult to arouse and has a
respiratory rate of 7/min. Which medication should the nurse anticipate
administering?
A. Flumazenil
B. Naloxone
C. Protamine sulfate
D. Vitamin K
Answer: B. Naloxone
Rationale: Naloxone is an opioid antagonist used to reverse opioid-induced
respiratory depression.
6. A nurse is preparing to administer insulin lispro. When should the
medication generally be administered?
,A. One hour before meals
B. At bedtime
C. Within approximately 15 minutes before a meal
D. Two hours after meals
Answer: C. Within approximately 15 minutes before a meal
Rationale: Lispro is rapid-acting insulin and should be given close to mealtime
to reduce the risk of hypoglycemia.
7. Which laboratory value should the nurse monitor most closely in a client
receiving enoxaparin?
A. Serum sodium
B. Serum calcium
C. Platelet count
D. Hemoglobin A1C
Answer: C. Platelet count
Rationale: Enoxaparin can cause thrombocytopenia, including heparin-
induced thrombocytopenia. Platelet monitoring helps identify this
complication.
8. A client taking lisinopril develops swelling of the lips and tongue. What is
the nurse's priority action?
A. Give the next dose with food
B. Place the client in Trendelenburg position
C. Hold the medication and obtain emergency assistance
D. Encourage oral fluids
Answer: C. Hold the medication and obtain emergency assistance
Rationale: Facial and tongue swelling can indicate angioedema, a potentially
life-threatening reaction that can obstruct the airway.
9. Which adverse effect is commonly associated with spironolactone?
A. Hypokalemia
B. Hyperkalemia
, C. Hypoglycemia
D. Hypernatremia
Answer: B. Hyperkalemia
Rationale: Spironolactone is a potassium-sparing diuretic and can increase
serum potassium levels.
10.A client taking atorvastatin reports severe muscle pain and weakness.
Which laboratory test should the nurse anticipate?
A. Amylase
B. Troponin
C. Creatine kinase (CK)
D. Bilirubin only
Answer: C. Creatine kinase (CK)
Rationale: Severe muscle pain may indicate myopathy or rhabdomyolysis. CK
levels help evaluate muscle injury.
11.Which instruction is appropriate for a client taking levothyroxine?
A. Take it with an iron supplement
B. Take it immediately after breakfast
C. Take it on an empty stomach, preferably in the morning
D. Stop taking it when symptoms improve
Answer: C. Take it on an empty stomach, preferably in the morning
Rationale: Levothyroxine is best absorbed on an empty stomach. Calcium and
iron can interfere with absorption and should be separated from the
medication.
12.A client taking metformin is scheduled for a procedure involving
iodinated contrast. What should the nurse anticipate?
A. Increasing the metformin dose
B. Temporarily withholding metformin according to the prescribed protocol
C. Giving metformin intravenously
D. Administering extra insulin automatically
Parenteral Therapies Exam 3 100
Questions And Correct Answers
(Verified Answers) Plus Rationales
2026 Q&A Instant Download Pdf
1. A client receiving digoxin reports nausea, anorexia, and seeing yellow-
green halos around lights. Which action should the nurse take first?
A. Administer the scheduled dose with food
B. Hold the digoxin and notify the provider
C. Encourage increased fluid intake
D. Administer an antacid
Answer: B. Hold the digoxin and notify the provider
Rationale: These findings are consistent with digoxin toxicity. The nurse
should withhold the medication and notify the provider.
2. Which assessment finding is most important for a client receiving
furosemide?
A. Increased appetite
B. Warm, flushed skin
C. Serum potassium of 2.8 mEq/L
D. Blood glucose of 110 mg/dL
Answer: C. Serum potassium of 2.8 mEq/L
Rationale: Furosemide can cause significant potassium loss. Severe
hypokalemia increases the risk of dysrhythmias and requires prompt
intervention.
, 3. A client prescribed warfarin asks which food should be consumed
consistently rather than avoided completely. Which food is appropriate?
A. Grapefruit
B. Spinach
C. Bananas
D. Milk
Answer: B. Spinach
Rationale: Spinach contains vitamin K, which can decrease warfarin's
anticoagulant effect. Clients should maintain a consistent intake of vitamin K
rather than abruptly changing consumption.
4. Which medication reverses the effects of heparin?
A. Vitamin K
B. Acetylcysteine
C. Naloxone
D. Protamine sulfate
Answer: D. Protamine sulfate
Rationale: Protamine sulfate is the antidote for unfractionated heparin.
Vitamin K is used to reverse warfarin.
5. A client receiving IV morphine becomes difficult to arouse and has a
respiratory rate of 7/min. Which medication should the nurse anticipate
administering?
A. Flumazenil
B. Naloxone
C. Protamine sulfate
D. Vitamin K
Answer: B. Naloxone
Rationale: Naloxone is an opioid antagonist used to reverse opioid-induced
respiratory depression.
6. A nurse is preparing to administer insulin lispro. When should the
medication generally be administered?
,A. One hour before meals
B. At bedtime
C. Within approximately 15 minutes before a meal
D. Two hours after meals
Answer: C. Within approximately 15 minutes before a meal
Rationale: Lispro is rapid-acting insulin and should be given close to mealtime
to reduce the risk of hypoglycemia.
7. Which laboratory value should the nurse monitor most closely in a client
receiving enoxaparin?
A. Serum sodium
B. Serum calcium
C. Platelet count
D. Hemoglobin A1C
Answer: C. Platelet count
Rationale: Enoxaparin can cause thrombocytopenia, including heparin-
induced thrombocytopenia. Platelet monitoring helps identify this
complication.
8. A client taking lisinopril develops swelling of the lips and tongue. What is
the nurse's priority action?
A. Give the next dose with food
B. Place the client in Trendelenburg position
C. Hold the medication and obtain emergency assistance
D. Encourage oral fluids
Answer: C. Hold the medication and obtain emergency assistance
Rationale: Facial and tongue swelling can indicate angioedema, a potentially
life-threatening reaction that can obstruct the airway.
9. Which adverse effect is commonly associated with spironolactone?
A. Hypokalemia
B. Hyperkalemia
, C. Hypoglycemia
D. Hypernatremia
Answer: B. Hyperkalemia
Rationale: Spironolactone is a potassium-sparing diuretic and can increase
serum potassium levels.
10.A client taking atorvastatin reports severe muscle pain and weakness.
Which laboratory test should the nurse anticipate?
A. Amylase
B. Troponin
C. Creatine kinase (CK)
D. Bilirubin only
Answer: C. Creatine kinase (CK)
Rationale: Severe muscle pain may indicate myopathy or rhabdomyolysis. CK
levels help evaluate muscle injury.
11.Which instruction is appropriate for a client taking levothyroxine?
A. Take it with an iron supplement
B. Take it immediately after breakfast
C. Take it on an empty stomach, preferably in the morning
D. Stop taking it when symptoms improve
Answer: C. Take it on an empty stomach, preferably in the morning
Rationale: Levothyroxine is best absorbed on an empty stomach. Calcium and
iron can interfere with absorption and should be separated from the
medication.
12.A client taking metformin is scheduled for a procedure involving
iodinated contrast. What should the nurse anticipate?
A. Increasing the metformin dose
B. Temporarily withholding metformin according to the prescribed protocol
C. Giving metformin intravenously
D. Administering extra insulin automatically
