NURS 615 2027 Exam 2 Questions and Answers
Question 1.
What are the pharmacodynamics of carbamazepine (Tegretol)?
Correct Answer: - Auto- metabolizes leading to lower serum levels despite
compliance.
- Half-life 30 hours as single dose, 15 hours when given repeatedly.
Question 2.
What are the Black Box Warnings for carbamazepine (Tegretol)?
Correct Answer: - Stevens- Johnson Syndrome (SJS)
- Toxic Epidermal Necrolysis (TEN)
Question 3.
Carbamazepine (Tegretol) is what type of drug?
Correct Answer: Anticonvulsant drug
Question 4.
What should families be taught regarding the monitoring of seizure activity?
Correct Answer: - Prevention of seizures
- Patient Safety
- Quality of life issues
- Do not discontinue medication due to increased risk of seizures
Question 5.
What electrolyte imbalance is noted with the administration of topiramate (Topamax)?
Correct Answer: Decrease in sodium bicarbonate leading to hyperchloremic
metabolic acidosis.
Question 6.
What are adverse effects of topiramate (Topamax)?
Correct Answer: - Weight loss, especially in higher dose patients
- May affect ability to sweat
• What are pregnancy precautions for valproate (Depakote)? -✓✓- Pregnancy
Category X
- Teratogen (an agent that causes malformation of an embryo)
, Question 7.
What instructions will you provide to a woman who wants to get pregnant and has a
seizure disorder controlled with valproate (Depakote)?
Correct Answer: - Pregnant women should be advised to switch to another
anticonvulsant during the first trimester, such as levetiracetam (Keppra), then
switch back to volproate (Depakote) in the second trimester.
- All anticonvulsants for pregnant women should be monitored by a high-risk
obstetrician.
Question 8.
What are precautions and contraindications for tricyclic antidepressants?
Correct Answer: - Caution cardiac disease patients (may act as an
antiarrhythmic)
- HTN, tachycardia, and convulsions when used with MAOIs
Question 9.
What are adverse effects of tricyclic antidepressants?
Correct Answer: - Anticholinergic effects (dry mouth, sedation, constipation,
increased appetite, blurred vision, tinnitus, euphoria, and mania)
Question 10.
Phenylzine (Nardil) is an MAOI. What are the precautions and contraindications?
Correct Answer: - Avoid foods high in tyramine (fermented foods, wine,
alcohol, aged cheeses, yogurt, soy sauce, summer sausage, processed meats,
etc.)
- Avoid St. John's Wort (Serotonin Syndrome)
-Many other drug-drug interactions
Question 11.
How long does it take to clear an MAOI from the body?
Correct Answer: 2 full weeks, 5 weeks before using fluoxetine (Prozac)
• What are the symptoms of hypertensive crisis? -✓✓Headache, heart
palpitations, stiff or sore neck, chest tightness, tachycardia, sweating, and
dilated pupils. Can be life threatening.
Question 12.
How long does it take for SSRIs to produce an effect for depression?
Correct Answer: 2 - 6 weeks (most are full effect at 4 weeks)
Question 1.
What are the pharmacodynamics of carbamazepine (Tegretol)?
Correct Answer: - Auto- metabolizes leading to lower serum levels despite
compliance.
- Half-life 30 hours as single dose, 15 hours when given repeatedly.
Question 2.
What are the Black Box Warnings for carbamazepine (Tegretol)?
Correct Answer: - Stevens- Johnson Syndrome (SJS)
- Toxic Epidermal Necrolysis (TEN)
Question 3.
Carbamazepine (Tegretol) is what type of drug?
Correct Answer: Anticonvulsant drug
Question 4.
What should families be taught regarding the monitoring of seizure activity?
Correct Answer: - Prevention of seizures
- Patient Safety
- Quality of life issues
- Do not discontinue medication due to increased risk of seizures
Question 5.
What electrolyte imbalance is noted with the administration of topiramate (Topamax)?
Correct Answer: Decrease in sodium bicarbonate leading to hyperchloremic
metabolic acidosis.
Question 6.
What are adverse effects of topiramate (Topamax)?
Correct Answer: - Weight loss, especially in higher dose patients
- May affect ability to sweat
• What are pregnancy precautions for valproate (Depakote)? -✓✓- Pregnancy
Category X
- Teratogen (an agent that causes malformation of an embryo)
, Question 7.
What instructions will you provide to a woman who wants to get pregnant and has a
seizure disorder controlled with valproate (Depakote)?
Correct Answer: - Pregnant women should be advised to switch to another
anticonvulsant during the first trimester, such as levetiracetam (Keppra), then
switch back to volproate (Depakote) in the second trimester.
- All anticonvulsants for pregnant women should be monitored by a high-risk
obstetrician.
Question 8.
What are precautions and contraindications for tricyclic antidepressants?
Correct Answer: - Caution cardiac disease patients (may act as an
antiarrhythmic)
- HTN, tachycardia, and convulsions when used with MAOIs
Question 9.
What are adverse effects of tricyclic antidepressants?
Correct Answer: - Anticholinergic effects (dry mouth, sedation, constipation,
increased appetite, blurred vision, tinnitus, euphoria, and mania)
Question 10.
Phenylzine (Nardil) is an MAOI. What are the precautions and contraindications?
Correct Answer: - Avoid foods high in tyramine (fermented foods, wine,
alcohol, aged cheeses, yogurt, soy sauce, summer sausage, processed meats,
etc.)
- Avoid St. John's Wort (Serotonin Syndrome)
-Many other drug-drug interactions
Question 11.
How long does it take to clear an MAOI from the body?
Correct Answer: 2 full weeks, 5 weeks before using fluoxetine (Prozac)
• What are the symptoms of hypertensive crisis? -✓✓Headache, heart
palpitations, stiff or sore neck, chest tightness, tachycardia, sweating, and
dilated pupils. Can be life threatening.
Question 12.
How long does it take for SSRIs to produce an effect for depression?
Correct Answer: 2 - 6 weeks (most are full effect at 4 weeks)
