NR507 / NR 507 Advanced Pathophysiology 2027 Midterm Exam - Full
Solution Study Guide with Exam Questions and Accurate Verified
Answers - Grade A+
Question 1.
The nurse practitioner (NP) reviews a client's laboratory results. Which laboratory result
best reflects the client's level of iron stores?
Transferrin saturation
Hemoglobin
Serum iron
Serum ferritin
Hematocrit
Total iron-binding capacity .
Answer: Serum ferritin
Question 2.
The nurse practitioner (NP) is caring for a client with beta thalassemia major. The NP
should anticipate the client will require what? .
Answer: a bloos transfusion
Question 3.
The nurse practitioner (NP) is counseling a client with iron deficiency anemia about
dietary needs. Which instruction(s) should the NP include? Select all that apply.
Avoid drinking tea or coffee with meals
Consume lean red meat Increase intake of calcium-rich foods
Consume iron-fortified cereal
Consume vitamin C-rich foods with iron-rich meals .
Answer: Avoid drinking tea or coffee with meals
Consume lean red meat
Consume iron-fortified cereal
Consume vitamin C-rich foods with iron-rich meals
Question 4.
A nurse practitioner (NP) is providing pre-conception counseling to a couple, both of
whom are carriers of thalassemia. Which of the following actions should the NP take?
Select all that apply.
Encourage the couple not to conceive.
Refer the couple for genetic counseling.
Explain what it means to be a carrier of thalassemia.
Discuss ways to prevent naturally conceiving a child with thalassemia.
Discuss inheritance patterns of thalassemia. .
,Answer: Refer the couple for genetic counseling.
Explain what it means to be a carrier of thalassemia.
Discuss inheritance patterns of thalassemia.
Question 5.
The nurse practitioner (NP) assesses the client on a follow-up visit after the initiation of
treatment for thalassemia including administration of blood transfusions. What three (3)
assessments should the NP prioritize to evaluate client outcomes? Select 3. Dietary
intake
Developmental milestones
Ferritin level
Hemoglobin level
Energy level .
Answer: Ferritin level
Hemoglobin level
Energy level
Question 6.
Which of the following clients should the nurse practitioner (NP) recognize as being most
at risk for developing vitamin B-12 deficiency anemia?
An infant who is exclusively breastfed
Middle adult client who eats a high-protein diet
A client who is pregnant
Adult client who had a vertical sleeve gastrectomy .
Answer: Adult client who had a vertical sleeve gastrectomy
Question 7.
Mean Corpuscular Hemoglobin Concentration (MCHC) .
Answer: indicates hemoglobin concentration in RBCs
Question 8.
Ferritin .
Answer: total iron stores; low levels indicate iron deficiency
Question 9.
microlytic anemia .
Answer: small RBC's
-iron deficiency
-thalassemia
‣ Thalassemia beta major treatment . Answer: blood transfusion- will increase
iron stores
, Chelation therapy-deferasirox & deferiprone
bone marrow transplant
Question 10.
Type 1 hypersensitivity .
Answer: Mediated by IgE antibody
Anaphylaxis, allergic rhinitis, asthma
Question 11.
Type 2 hypersensitivity .
Answer: mediated by IgG antibodies and macrophages
HITT reaction, transfusion reaction, Graves Disease
Question 12.
Graves disease .
Answer: IgG antibodies attach the TSH receptor causing an over production of
thyroid hormones leading the hyperthyroidism
tx: beta blockers for tachycardia, methimazole (not for pregnant),
propylthiouracil (for pregnant), radioactive iodine therapy (not for pregnant)
Question 13.
Type 3 hypersensitivity .
Answer: neutrophil mediated reaction
immune complexes activate complement system & neutrophils resulting in
tissue destruction
-Lupus, serum sickness
Question 14.
systemic lupus erythematosus .
Answer: B&T cells are over reactive causing production of antibodies
DX with ANA antibody TX with NSAIDS for pain
Question 15.
Which of the following client(s) should the nurse practitioner (NP) recognize as being at
risk for developing folate deficiency? Select all that apply.
A 30-year-old client with severe anorexia nervosa
A 19-year-old client with sickle cell disease
A 27-year-old client who is newly pregnant and breastfeeding their toddler
A 40-year-old client with celiac disease
Solution Study Guide with Exam Questions and Accurate Verified
Answers - Grade A+
Question 1.
The nurse practitioner (NP) reviews a client's laboratory results. Which laboratory result
best reflects the client's level of iron stores?
Transferrin saturation
Hemoglobin
Serum iron
Serum ferritin
Hematocrit
Total iron-binding capacity .
Answer: Serum ferritin
Question 2.
The nurse practitioner (NP) is caring for a client with beta thalassemia major. The NP
should anticipate the client will require what? .
Answer: a bloos transfusion
Question 3.
The nurse practitioner (NP) is counseling a client with iron deficiency anemia about
dietary needs. Which instruction(s) should the NP include? Select all that apply.
Avoid drinking tea or coffee with meals
Consume lean red meat Increase intake of calcium-rich foods
Consume iron-fortified cereal
Consume vitamin C-rich foods with iron-rich meals .
Answer: Avoid drinking tea or coffee with meals
Consume lean red meat
Consume iron-fortified cereal
Consume vitamin C-rich foods with iron-rich meals
Question 4.
A nurse practitioner (NP) is providing pre-conception counseling to a couple, both of
whom are carriers of thalassemia. Which of the following actions should the NP take?
Select all that apply.
Encourage the couple not to conceive.
Refer the couple for genetic counseling.
Explain what it means to be a carrier of thalassemia.
Discuss ways to prevent naturally conceiving a child with thalassemia.
Discuss inheritance patterns of thalassemia. .
,Answer: Refer the couple for genetic counseling.
Explain what it means to be a carrier of thalassemia.
Discuss inheritance patterns of thalassemia.
Question 5.
The nurse practitioner (NP) assesses the client on a follow-up visit after the initiation of
treatment for thalassemia including administration of blood transfusions. What three (3)
assessments should the NP prioritize to evaluate client outcomes? Select 3. Dietary
intake
Developmental milestones
Ferritin level
Hemoglobin level
Energy level .
Answer: Ferritin level
Hemoglobin level
Energy level
Question 6.
Which of the following clients should the nurse practitioner (NP) recognize as being most
at risk for developing vitamin B-12 deficiency anemia?
An infant who is exclusively breastfed
Middle adult client who eats a high-protein diet
A client who is pregnant
Adult client who had a vertical sleeve gastrectomy .
Answer: Adult client who had a vertical sleeve gastrectomy
Question 7.
Mean Corpuscular Hemoglobin Concentration (MCHC) .
Answer: indicates hemoglobin concentration in RBCs
Question 8.
Ferritin .
Answer: total iron stores; low levels indicate iron deficiency
Question 9.
microlytic anemia .
Answer: small RBC's
-iron deficiency
-thalassemia
‣ Thalassemia beta major treatment . Answer: blood transfusion- will increase
iron stores
, Chelation therapy-deferasirox & deferiprone
bone marrow transplant
Question 10.
Type 1 hypersensitivity .
Answer: Mediated by IgE antibody
Anaphylaxis, allergic rhinitis, asthma
Question 11.
Type 2 hypersensitivity .
Answer: mediated by IgG antibodies and macrophages
HITT reaction, transfusion reaction, Graves Disease
Question 12.
Graves disease .
Answer: IgG antibodies attach the TSH receptor causing an over production of
thyroid hormones leading the hyperthyroidism
tx: beta blockers for tachycardia, methimazole (not for pregnant),
propylthiouracil (for pregnant), radioactive iodine therapy (not for pregnant)
Question 13.
Type 3 hypersensitivity .
Answer: neutrophil mediated reaction
immune complexes activate complement system & neutrophils resulting in
tissue destruction
-Lupus, serum sickness
Question 14.
systemic lupus erythematosus .
Answer: B&T cells are over reactive causing production of antibodies
DX with ANA antibody TX with NSAIDS for pain
Question 15.
Which of the following client(s) should the nurse practitioner (NP) recognize as being at
risk for developing folate deficiency? Select all that apply.
A 30-year-old client with severe anorexia nervosa
A 19-year-old client with sickle cell disease
A 27-year-old client who is newly pregnant and breastfeeding their toddler
A 40-year-old client with celiac disease
