NAPLEX Compounding Questions with Correct Answers (Grade A+)
Question 1: A pharmacy cannot compound a ___ product.
Answer: commercially available
Question 2: Who sets the standards for compounding?
Answer: USP - minimum acceptable standards; ASHP implementation standards
Question 3: What routes are nonsterile?
Answer: PO, per tube, rectal, vaginal, topical, nasal, otic (unless eardrum perforation)
Question 4: simple compounding
Answer: follow instructions in a compounding kit
Question 5: moderate compounding
Answer: special calculations/procedures and/or no stability data
Question 6: complex compounding
Answer: requires special training, equipment, facilities, procedures (ex. transdermal)
Question 7: Where should non-sterile compounding be conducted?
Answer: specific space separate from the dispensing area with potable water and purified water and all
equipment stored off of the floor
Question 8: What is potable water used for?
Answer: hand and equipment washing
Question 9: What is purified water used for?
Answer: aka distilled; water formulations, rinsing equipment
Question 10: What routes require sterile compounding?
Answer: IV, IM, subQ, eye drops, irrigations, pulmonary inhalations (not nasal)
Page 1
,Question 11: CSP
Answer: compounded sterile product
Question 12: SVP
Answer: small volume parenteral; d100 mL
Question 13: LVP
Answer: large volume parenteral; >100mL
Question 14: PEC
Answer: primary engineering control (ISO-5)
Question 15: LAFW
Answer: laminar airflow workbench
Question 16: C-PEC
Answer: containment primary engineering control
Question 17: BSC
Answer: biological safety cabinet (type of C-PEC); vertical laminar flow; negative pressure
Question 18: SEC
Answer: secondary engineering control (ISO 7 buffer room)
Question 19: C-SEC
Answer: containment secondary engineering control
Question 20: SCA
Answer: segregated compounding area - glovebox within unclassified air
Question 21: C-SCA
Answer: containment segregated compounding area
Page 2
, Question 22: CAI
Answer: compounding aseptic isolator
Question 23: CACI
Answer: compounding aseptic containment isolator
Question 24: RABS
Answer: restricted access barrier system (glovebox)
Question 25: CSTD
Answer: closed system transfer device
Question 26: CVE
Answer: containment ventilated enclosure; used for nonsterile hazardous compounding
Question 27: Who determines required particle counts/air quality standards?
Answer: ISO
Question 28: What size is a "particle"?
Answer: e0.5 microns
Question 29: air quality PEC
Answer: ISO 5
Question 30: air quality SEC
Answer: ISO 7
Question 31: air quality anteroom
Answer: ISO 8 if positive pressure; ISO 7 if negative pressure
Question 32: HEPA filters are ___ efficient in removing particles of ___
Answer: 99.97%; e0.3 microns
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Question 1: A pharmacy cannot compound a ___ product.
Answer: commercially available
Question 2: Who sets the standards for compounding?
Answer: USP - minimum acceptable standards; ASHP implementation standards
Question 3: What routes are nonsterile?
Answer: PO, per tube, rectal, vaginal, topical, nasal, otic (unless eardrum perforation)
Question 4: simple compounding
Answer: follow instructions in a compounding kit
Question 5: moderate compounding
Answer: special calculations/procedures and/or no stability data
Question 6: complex compounding
Answer: requires special training, equipment, facilities, procedures (ex. transdermal)
Question 7: Where should non-sterile compounding be conducted?
Answer: specific space separate from the dispensing area with potable water and purified water and all
equipment stored off of the floor
Question 8: What is potable water used for?
Answer: hand and equipment washing
Question 9: What is purified water used for?
Answer: aka distilled; water formulations, rinsing equipment
Question 10: What routes require sterile compounding?
Answer: IV, IM, subQ, eye drops, irrigations, pulmonary inhalations (not nasal)
Page 1
,Question 11: CSP
Answer: compounded sterile product
Question 12: SVP
Answer: small volume parenteral; d100 mL
Question 13: LVP
Answer: large volume parenteral; >100mL
Question 14: PEC
Answer: primary engineering control (ISO-5)
Question 15: LAFW
Answer: laminar airflow workbench
Question 16: C-PEC
Answer: containment primary engineering control
Question 17: BSC
Answer: biological safety cabinet (type of C-PEC); vertical laminar flow; negative pressure
Question 18: SEC
Answer: secondary engineering control (ISO 7 buffer room)
Question 19: C-SEC
Answer: containment secondary engineering control
Question 20: SCA
Answer: segregated compounding area - glovebox within unclassified air
Question 21: C-SCA
Answer: containment segregated compounding area
Page 2
, Question 22: CAI
Answer: compounding aseptic isolator
Question 23: CACI
Answer: compounding aseptic containment isolator
Question 24: RABS
Answer: restricted access barrier system (glovebox)
Question 25: CSTD
Answer: closed system transfer device
Question 26: CVE
Answer: containment ventilated enclosure; used for nonsterile hazardous compounding
Question 27: Who determines required particle counts/air quality standards?
Answer: ISO
Question 28: What size is a "particle"?
Answer: e0.5 microns
Question 29: air quality PEC
Answer: ISO 5
Question 30: air quality SEC
Answer: ISO 7
Question 31: air quality anteroom
Answer: ISO 8 if positive pressure; ISO 7 if negative pressure
Question 32: HEPA filters are ___ efficient in removing particles of ___
Answer: 99.97%; e0.3 microns
Page 3
