MSN 611-Pharmacology for APRN Questions and Answers

MSN 611-Pharmacology for APRN Questions and Answers Second generation antihistamine that cannot be removed by hemodialysis Cetirizine How is enterobiasis diagnosed? Perianal swab examination for eggs Treatment modalities of tuberculosis directly observed therapy to ensure adherence to drug regimen (if the regimen is less than daily); if patient has a decline provider should ensure no drug resistance, proper compliance, and no interactions According to the universal prescribing alerts for ahminoglycosides extended use increases risk for infection by which of the pathogens C. difficile Mode of administration of dactinomycin dactinomycin is a vesicant that should only be administered intravenously to prevent extravasation Which of the following is an FDA approved indication for m methotrexate? Breast cancer, meningeal leukemia, & trophoblastic neoplasms Synthetic muscarinic receptor antagonist that possess M3 receptor selectivity The synthetic derivatives possessing some degree of M3 receptor selectivity include the newer agents darifenacin and solifenacin Autonomic agents associated stimulation of insulin production, increase glycogenolysis in the liver, and complicate the management of diabetes mellitus? Sympathomimentic autonomic agents may also stimulate insulin production, increase glycogenolysis in the liver and complicate the management of diabetes mellitus Most commonly used therapy for iron deficiency anemia ferrous sulfate Fatalities have occurred with the test dose of which drug iron dextran Antilipemic agent that targets triglycerides Fibrates Mechanism of action of calcium channel blocking agents act on calcium channels in the large vessels to produce vasodilation and subsequent reduction in blood pressure Hypotensive agent FDA approved for treatment of ADHD Extended release guanfacine When prescribing benzodiazepines, only lorazepam, oxazepam, or temazepam should be considered for which patients hepatic impairment Lithium is used as a treatment for: Mania, or depressive symptoms in bipolar disorder An important consideration when administering total parenteral nutrition peripherally is that: it should have a lower osmolality than for a central line choose the correct statement regarding diuretics thiazide diuretics work in the distal tubule In asthma patients, bronchospasm occur when an irritant interacts with arachidonic acid Which of the following statements correctly describes hydromorphone? it is more potent and has lower dosage requirements than morphine Which drug acts as a tyrosine inhibitor? Nintedanib Which of the following is true regarding proper technique and precautions for the administration of eye drops? Explain the proper administration technique for the concurrent use of eye drops and the reasoning behind this recommended technique. The sterility of drops maybe altered if contact is made with the eye. All of the above Choose the correct statement describing pilocarpine. It acts on the ciliary muscle Which of the following midriatic drugs is associated with increased risk for seizures? Cyclopentolate Which of the following is used as adjunctive therapy in the treatment of diarrhea? Diphenoxylate The use of mineral oil as a laxative has been largely replaced by the use of: osmotic laxatives Chronic use of which drug is associated with increased risk for tar dive dyskinesia? Metoclopramide What is the mechanism of action of thiazolidinediones? Increase the number of insulin receptors on cells Which of the following drugs acts as a dopamine agonist? Cabergoline Which of the following is a characteristic of mucosal membrane? It produces antibacterial enzymes Choose the correct statement describing topical anti-infective agents. Many are associated with hepatic dysfunction Which potential side effect is associated with isotretinoin? Marked elevations of serum triglycerides Which of the following is a potential adverse effect of mirabegron? arrhythmia & tachycardia Methylxanthines are structurally related to: Caffeine Theophylline toxicity is characterized by: repetitive vomiting Intranasal products should be used after a patient has tried an ____________ and are most effective when used regularly. intranasal glucocorticoid most significant adverse reactions associated with the use of hematopoietic agents are infusion related reactions causing significant hypotension or bradycardia Sildenafil's mechanism of action is to inhibit PDE-5 and increase intracellular concentration of_______ cyclic guanosine monophosphate (cGMP) drug-drug interactions between first generation antihistamines and monoamine oxidase and appropriate prescribing protocol of first generation antihistamines to patients who take MAOIs Because monoamine oxidase inhibitors (MAOIs) can also exacerbate anticholinergic side effect, first generation antihistamines should not be used during treatment or within 2 weeks of MAOI discontinuation In the stomach, histamine is released by enterochromaffin like cells When does tumor fear occur? Associated symptoms? Tumor flare is a side effect that may occur during initial phase of hormonal treatment. Symptoms: sudden and painful increase in the tumor size, rash, low grade fever, hypercalcemia, bone pain, and increase in tumor marker levels Potential adverse side effect of autonomic-anticholinergic agents in older males may have symptoms of benign prostatic hypertrophy due to worsening urinary retention