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NUR206
PHARMACOLOGY FINAL EXAM
127 PRACTICE QUESTIONS
2026/2027 EDITION
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127 Questions | Answers & Rationales for Study
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NUR206 • Pharmacology Practice Exam 2026/2027 | 1
,Section 1: Brief Introduction
This independently authored NUR206 pharmacology practice exam reviews medication safety,
pharmacokinetics, dosage calculations, major drug classes, patient education, and special-
population considerations. It is not an official, authenticated, or institution-endorsed
examination and does not reproduce live exam questions; verify medication decisions against
current course materials, drug references, prescriber orders, and local policy.
Section 2: The Complete Exam
Select the single best answer. Answers and rationales are integrated for study; correct choices
are highlighted.
1. A patient takes an enzyme-inducing medication and starts another drug. The nurse
should consider that the inducer may:
A. Prevent all drug interactions
B. Lower concentrations of some drugs by increasing metabolism
C. Always increase the other drug level
D. Have no effect on metabolism
Rationale: Enzyme induction can reduce concentrations of susceptible drugs; evaluate specific interactions
with a reliable reference.
2. A patient prescribed clonidine should be cautioned not to stop it abruptly because:
A. Rebound hypertension can occur
B. It causes permanent hypoglycemia
C. It eliminates the need for blood-pressure checks
D. It causes immediate anticoagulation
Rationale: Abrupt clonidine withdrawal can cause rebound hypertension; taper only under prescriber
guidance.
3. A 1,000-mL infusion is ordered over 10 hours with a 15-gtt/mL set. What is the
approximate rate in gtt/min?
A. 25 gtt/min
B. 15 gtt/min
C. 10 gtt/min
D. 40 gtt/min
Rationale: (1,000 mL × 15 gtt/mL) ÷ 600 min = 25 gtt/min.
4. A patient taking levothyroxine should be instructed to take it:
A. With calcium and iron to improve absorption
B. Consistently on an empty stomach, separated from calcium and iron
C. Only when fatigue occurs
NUR206 • Pharmacology Practice Exam 2026/2027 | 2
, D. At varying times with meals
Rationale: Food, calcium, and iron can reduce absorption; consistent administration and follow-up thyroid
testing are important.
5. A nurse is preparing a medication for a patient with a documented severe allergy to that
drug. What is the safest action?
A. Give a smaller dose
B. Hold it and clarify with the prescriber/pharmacist before administration
C. Ask the patient to sign a waiver
D. Administer with an antihistamine without an order
Rationale: A severe allergy is a potential contraindication; prevent exposure and clarify the order.
6. A patient taking an oral bisphosphonate should:
A. Take it with milk and lie down
B. Take it with plain water and remain upright for the instructed period
C. Chew it with breakfast
D. Take it with calcium at the same time
Rationale: Correct administration reduces esophageal irritation and supports absorption; calcium should be
separated.
7. A patient starts a new medication and develops a widespread blistering rash with
mouth sores. What should the nurse do?
A. Recommend a moisturizer and continue doses
B. Wait for the next appointment
C. Treat as a severe cutaneous reaction and arrange emergency evaluation
D. Take an extra dose with food
Rationale: Blistering rash and mucosal involvement can signal a life-threatening drug reaction; stop further
exposure pending urgent care.
8. A patient taking an opioid is difficult to arouse with respirations 7/min. What is the
priority?
A. Give the next opioid dose
B. Offer oral fluids
C. Support airway and breathing, activate emergency response, and give naloxone per
protocol
D. Wait one hour and reassess
Rationale: Opioid-induced respiratory depression is an emergency; prioritize ventilation and naloxone while
monitoring for recurrence.
9. A patient taking loperamide has bloody diarrhea and fever. The nurse should:
A. Avoid further self-treatment and seek medical evaluation
NUR206 • Pharmacology Practice Exam 2026/2027 | 3
· · · · · · · ·
━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
NUR206
PHARMACOLOGY FINAL EXAM
127 PRACTICE QUESTIONS
2026/2027 EDITION
━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
127 Questions | Answers & Rationales for Study
◆ ◇ ◆
· · · · · · ·
◆
NUR206 • Pharmacology Practice Exam 2026/2027 | 1
,Section 1: Brief Introduction
This independently authored NUR206 pharmacology practice exam reviews medication safety,
pharmacokinetics, dosage calculations, major drug classes, patient education, and special-
population considerations. It is not an official, authenticated, or institution-endorsed
examination and does not reproduce live exam questions; verify medication decisions against
current course materials, drug references, prescriber orders, and local policy.
Section 2: The Complete Exam
Select the single best answer. Answers and rationales are integrated for study; correct choices
are highlighted.
1. A patient takes an enzyme-inducing medication and starts another drug. The nurse
should consider that the inducer may:
A. Prevent all drug interactions
B. Lower concentrations of some drugs by increasing metabolism
C. Always increase the other drug level
D. Have no effect on metabolism
Rationale: Enzyme induction can reduce concentrations of susceptible drugs; evaluate specific interactions
with a reliable reference.
2. A patient prescribed clonidine should be cautioned not to stop it abruptly because:
A. Rebound hypertension can occur
B. It causes permanent hypoglycemia
C. It eliminates the need for blood-pressure checks
D. It causes immediate anticoagulation
Rationale: Abrupt clonidine withdrawal can cause rebound hypertension; taper only under prescriber
guidance.
3. A 1,000-mL infusion is ordered over 10 hours with a 15-gtt/mL set. What is the
approximate rate in gtt/min?
A. 25 gtt/min
B. 15 gtt/min
C. 10 gtt/min
D. 40 gtt/min
Rationale: (1,000 mL × 15 gtt/mL) ÷ 600 min = 25 gtt/min.
4. A patient taking levothyroxine should be instructed to take it:
A. With calcium and iron to improve absorption
B. Consistently on an empty stomach, separated from calcium and iron
C. Only when fatigue occurs
NUR206 • Pharmacology Practice Exam 2026/2027 | 2
, D. At varying times with meals
Rationale: Food, calcium, and iron can reduce absorption; consistent administration and follow-up thyroid
testing are important.
5. A nurse is preparing a medication for a patient with a documented severe allergy to that
drug. What is the safest action?
A. Give a smaller dose
B. Hold it and clarify with the prescriber/pharmacist before administration
C. Ask the patient to sign a waiver
D. Administer with an antihistamine without an order
Rationale: A severe allergy is a potential contraindication; prevent exposure and clarify the order.
6. A patient taking an oral bisphosphonate should:
A. Take it with milk and lie down
B. Take it with plain water and remain upright for the instructed period
C. Chew it with breakfast
D. Take it with calcium at the same time
Rationale: Correct administration reduces esophageal irritation and supports absorption; calcium should be
separated.
7. A patient starts a new medication and develops a widespread blistering rash with
mouth sores. What should the nurse do?
A. Recommend a moisturizer and continue doses
B. Wait for the next appointment
C. Treat as a severe cutaneous reaction and arrange emergency evaluation
D. Take an extra dose with food
Rationale: Blistering rash and mucosal involvement can signal a life-threatening drug reaction; stop further
exposure pending urgent care.
8. A patient taking an opioid is difficult to arouse with respirations 7/min. What is the
priority?
A. Give the next opioid dose
B. Offer oral fluids
C. Support airway and breathing, activate emergency response, and give naloxone per
protocol
D. Wait one hour and reassess
Rationale: Opioid-induced respiratory depression is an emergency; prioritize ventilation and naloxone while
monitoring for recurrence.
9. A patient taking loperamide has bloody diarrhea and fever. The nurse should:
A. Avoid further self-treatment and seek medical evaluation
NUR206 • Pharmacology Practice Exam 2026/2027 | 3
