TEST BANK FOR ABRAMS’ CLINICAL DRUG
THERAPY RATIONALES FOR NURSING
PRACTICE 12TH EDITION GERALYN FRANDSEN -
ISBN/ISSN 9781975136130
# TEST BANK FOR ABRAMS' CLINICAL DRUG THERAPY RATIONALES FOR NURSING PRACTICE 12TH
EDITION GERALYN FRANDSEN
---
## Chapter 1: The Foundation of Pharmacology: Quality and Safety
**1. A woman diagnosed with obsessive-compulsive disorder has been prescribed oral paroxetine
hydrochloride. What is the expected effect for this prescription?**
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
**ANS: B**
**Rationale:** Drugs that produce systemic effects are taken into the body, circulated through the
bloodstream to their sites of action in various body tissues, and eventually eliminated from the body.
Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride will control
the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen and local
anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not administered
parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or intravenously.
,---
**2. A client has been prescribed an antibiotic. This medication is a naturally occurring substance that
has been chemically modified. What is another name for this type of medication?**
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
**ANS: B**
**Rationale:** Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that have
been chemically modified. Synthetic drugs are more standardized in their chemical characteristics, more
consistent in their effects, and less likely to produce allergic reactions. Biotechnology drugs involve
manipulating DNA and RNA and recombining genes into hybrid molecules that can be inserted into living
organisms. Prototype drugs are the first drug of a particular group to be developed.
---
**3. Which classification applies to morphine?**
A. Central nervous system depressant
B. Central nervous system stimulant
C. Anti-inflammatory
D. Antihypertensive
**ANS: A**
,**Rationale:** Drugs are classified according to their effects on particular body systems, their
therapeutic uses, and their chemical characteristics. Morphine is classified as a central nervous system
depressant and will produce this effect in the client. A central nervous system stimulant increases
attention and raises mood. An anti-inflammatory agent decreases inflammation at the site of tissue or
joint inflammation. An antihypertensive agent reduces blood pressure.
---
**4. A client is administered amoxicillin. The generic name of this medication belongs to which drug
group?**
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
**ANS: C**
**Rationale:** The generic name often indicates the drug group (e.g., drugs with generic names ending
in "cillin" are penicillins). Selective serotonin reuptake inhibitors are medications that have
antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are medications that
increase urine output; diuretic is a broad classification, not a generic name. ACE inhibitor is the broad
classification for the angiotensin receptor blockers, not the generic name.
---
**5. The administration of diphenhydramine is regulated by which U.S. government agency?**
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug Administration
, **ANS: D**
**Rationale:** The Food and Drug Administration is the U.S. government agency that regulates the
administration of diphenhydramine.
---
**6. In the U.S., the administration of anabolic steroids is regulated by which law?**
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
**ANS: B**
**Rationale:** The Comprehensive Drug Abuse Prevention and Control Act regulates the manufacture
and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic steroids. The Food,
Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and responsibilities, giving the FDA
control over drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale, and
use of opium, cocaine, marijuana, and other drugs that the act defined as narcotics. The Sherley
Amendment of 1912 prohibited fraudulent claims of drug effectiveness.
---
**7. A nurse is responsible for maintaining an accurate count and record of the controlled substances on
the nursing division. This nursing action is regulated by which U.S. law or agency?**
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
THERAPY RATIONALES FOR NURSING
PRACTICE 12TH EDITION GERALYN FRANDSEN -
ISBN/ISSN 9781975136130
# TEST BANK FOR ABRAMS' CLINICAL DRUG THERAPY RATIONALES FOR NURSING PRACTICE 12TH
EDITION GERALYN FRANDSEN
---
## Chapter 1: The Foundation of Pharmacology: Quality and Safety
**1. A woman diagnosed with obsessive-compulsive disorder has been prescribed oral paroxetine
hydrochloride. What is the expected effect for this prescription?**
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
**ANS: B**
**Rationale:** Drugs that produce systemic effects are taken into the body, circulated through the
bloodstream to their sites of action in various body tissues, and eventually eliminated from the body.
Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride will control
the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen and local
anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not administered
parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or intravenously.
,---
**2. A client has been prescribed an antibiotic. This medication is a naturally occurring substance that
has been chemically modified. What is another name for this type of medication?**
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
**ANS: B**
**Rationale:** Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that have
been chemically modified. Synthetic drugs are more standardized in their chemical characteristics, more
consistent in their effects, and less likely to produce allergic reactions. Biotechnology drugs involve
manipulating DNA and RNA and recombining genes into hybrid molecules that can be inserted into living
organisms. Prototype drugs are the first drug of a particular group to be developed.
---
**3. Which classification applies to morphine?**
A. Central nervous system depressant
B. Central nervous system stimulant
C. Anti-inflammatory
D. Antihypertensive
**ANS: A**
,**Rationale:** Drugs are classified according to their effects on particular body systems, their
therapeutic uses, and their chemical characteristics. Morphine is classified as a central nervous system
depressant and will produce this effect in the client. A central nervous system stimulant increases
attention and raises mood. An anti-inflammatory agent decreases inflammation at the site of tissue or
joint inflammation. An antihypertensive agent reduces blood pressure.
---
**4. A client is administered amoxicillin. The generic name of this medication belongs to which drug
group?**
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
**ANS: C**
**Rationale:** The generic name often indicates the drug group (e.g., drugs with generic names ending
in "cillin" are penicillins). Selective serotonin reuptake inhibitors are medications that have
antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are medications that
increase urine output; diuretic is a broad classification, not a generic name. ACE inhibitor is the broad
classification for the angiotensin receptor blockers, not the generic name.
---
**5. The administration of diphenhydramine is regulated by which U.S. government agency?**
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug Administration
, **ANS: D**
**Rationale:** The Food and Drug Administration is the U.S. government agency that regulates the
administration of diphenhydramine.
---
**6. In the U.S., the administration of anabolic steroids is regulated by which law?**
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
**ANS: B**
**Rationale:** The Comprehensive Drug Abuse Prevention and Control Act regulates the manufacture
and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic steroids. The Food,
Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and responsibilities, giving the FDA
control over drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale, and
use of opium, cocaine, marijuana, and other drugs that the act defined as narcotics. The Sherley
Amendment of 1912 prohibited fraudulent claims of drug effectiveness.
---
**7. A nurse is responsible for maintaining an accurate count and record of the controlled substances on
the nursing division. This nursing action is regulated by which U.S. law or agency?**
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
