NR 547 Chamberlain University-Illinois NR
547 Final Exam Exam Prep with Practice
Questions, Answers & Detailed
Explanations
Treatment of depression in postpartum women
Mild depression
Psychotherapy such as cognitive-behavioral therapy
(CBT) OR interpersonal therapy
Mild Depression postpartum while breast-
feeding
Psychotherapy with or without antidepressant
(sertraline or paroxetine)
Severe Depression
Psychotherapy AND fluoxetine
,Alternative medications: sertraline or tricyclic
antidepressant.
Severe Depression postpartum while breast-
feeding
Supportive services AND sertraline
Alternative medication: Paroxetine
Medications for depression with MOA
Selective Serotonin Reuptake Inhibitors (SSRI's)
inhibit 5-HT reuptake
Serotonin Norepinephrine Reuptake Inhibitors
(SNRIs)
inhibit 5-HT reuptakeinhibit NE reuptake (↑ energy,
focus)
increase DA in prefrontal cortex (↑ cognition)
Norepinephrine Dopamine Reuptake Inhibitors
(NDRI)
inhibit DA reuptake (↑alertness, motivation)
inhibit NE reuptake (↑energy)
Prescribing Pearl: Escitalopram (Lexapro)
,no known drug interactions
Prescribing Pearl: Citalopram (Celexa)
mild antihistamine effects
Prescribing Pearl: Fluoxetine (Prozac)
longest half-life
Prescribing Pearl: Paroxetine (Paxil)
also treats social anxiety and insomnia
Prescribing Pearl: Fluvoxamine (Luvox)
treats anxious depression smokers require increased
dose
Prescribing Pearl: Sertraline (Zoloft)
also treats social anxiety and hypersomnolence
Prescribing Pearl: Venlafaxine (Effexor)
treats both depression and anxiety disorders, ensure
trial of higher dose before switching to a different
medication
Prescribing Pearl: Desvenlafaxine (Pristiq)
effective for perimenopausal vasomotor symptoms
, Prescribing Pearl: Duloxetine (Cymbalta)
effective for atypical pain at higher doses;
appropriate for clients who present with somatic
symptoms of depression; effective for atypical pain,
such as fibromyalgia and diabetic neuropathy
Prescribing Pearl: Bupropion (Wellbutrin)- NDRI
may improve energy, alertness, and motivation; not
first line treatment for anxiety; contraindicated in
clients with a history of seizures
Choosing an antidepressant:
1) selection of primary agent (consider co-
morbidities, past treatment response, side effects,
etc.)
2) Gradually increase dose
3) Switch to a different drug within the same class
4) Switch to a drug in a different class
5) Add a second medication and/or mood stabilizer
depression
mood disorder characterized by depressive
symptoms lasting longer than 2 weeks. It has been
547 Final Exam Exam Prep with Practice
Questions, Answers & Detailed
Explanations
Treatment of depression in postpartum women
Mild depression
Psychotherapy such as cognitive-behavioral therapy
(CBT) OR interpersonal therapy
Mild Depression postpartum while breast-
feeding
Psychotherapy with or without antidepressant
(sertraline or paroxetine)
Severe Depression
Psychotherapy AND fluoxetine
,Alternative medications: sertraline or tricyclic
antidepressant.
Severe Depression postpartum while breast-
feeding
Supportive services AND sertraline
Alternative medication: Paroxetine
Medications for depression with MOA
Selective Serotonin Reuptake Inhibitors (SSRI's)
inhibit 5-HT reuptake
Serotonin Norepinephrine Reuptake Inhibitors
(SNRIs)
inhibit 5-HT reuptakeinhibit NE reuptake (↑ energy,
focus)
increase DA in prefrontal cortex (↑ cognition)
Norepinephrine Dopamine Reuptake Inhibitors
(NDRI)
inhibit DA reuptake (↑alertness, motivation)
inhibit NE reuptake (↑energy)
Prescribing Pearl: Escitalopram (Lexapro)
,no known drug interactions
Prescribing Pearl: Citalopram (Celexa)
mild antihistamine effects
Prescribing Pearl: Fluoxetine (Prozac)
longest half-life
Prescribing Pearl: Paroxetine (Paxil)
also treats social anxiety and insomnia
Prescribing Pearl: Fluvoxamine (Luvox)
treats anxious depression smokers require increased
dose
Prescribing Pearl: Sertraline (Zoloft)
also treats social anxiety and hypersomnolence
Prescribing Pearl: Venlafaxine (Effexor)
treats both depression and anxiety disorders, ensure
trial of higher dose before switching to a different
medication
Prescribing Pearl: Desvenlafaxine (Pristiq)
effective for perimenopausal vasomotor symptoms
, Prescribing Pearl: Duloxetine (Cymbalta)
effective for atypical pain at higher doses;
appropriate for clients who present with somatic
symptoms of depression; effective for atypical pain,
such as fibromyalgia and diabetic neuropathy
Prescribing Pearl: Bupropion (Wellbutrin)- NDRI
may improve energy, alertness, and motivation; not
first line treatment for anxiety; contraindicated in
clients with a history of seizures
Choosing an antidepressant:
1) selection of primary agent (consider co-
morbidities, past treatment response, side effects,
etc.)
2) Gradually increase dose
3) Switch to a different drug within the same class
4) Switch to a drug in a different class
5) Add a second medication and/or mood stabilizer
depression
mood disorder characterized by depressive
symptoms lasting longer than 2 weeks. It has been
