Advanced
Pathophysiology Study
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, 3 urate accumulation 4 Metaplasia
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Terms in this set (93)
Atrophy E. Cells decrease in size
P. Still functional
Physiologic: thymus gland in early childhood
Pathological: disuse
Hypertrophy E. Increase in cell size
P. Increased workload
Physiologic: weightlifting
Pathologic: cardiomegaly from HTN
Hyperplasia E. Increase in cell number
P. Increased cellular division
Physiologic: liver regeneration
Pathologic: endometrial- usually r/t hormones
Dysplasia E. Cells change in size, shape, organization
P. AKA atypical hyperplasia, a disorderly proliferation
Physiologic: N/A
Pathologic: squamous dysplasia of cervix from HPV
Metaplasia E. one cell type replaced with another
P. reprogramming of stem cells, reversible
Physiologic: N/A
Pathologic: stratified squamous cells in bronchial lining r/t cigarette smoke
Hypoxia injury E. inadequate oxygenation of tissues
P. decrease in mitochondrial function, decreased production of ATP increases
anaerobic metabolism. eventual cell death.
C.M. hypoxia, cyanosis, cognitive impairment, lethargy
Free radical and ROS E. normal byproduct of ATP production, will overwhelm the mitochondria-
exhaust intracellular antioxidants
P. lipid peroxidation, damage proteins, fragment DNA
C.M. development in Alzheimer's, heart disease, Parkinson's disease,
Amyotrophic Lateral Sclerosis