TestBankForClayton’sBasicPharmacologyforNurses19th
Edition
ByMichelleJ.Willihnganz,SamuelL.Gurevitz,BruceClayton
Complete
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz: Clayton
zi zi zi zi zi zi zi zi zi
’s Basic Pharmacology for Nurses, 19th Edition
zi zi zi zi zi zi
MULTIPLE CHOICE zi
1. Which name identifies a drug listed bythe US Food and
zi zi zi zi zi zi zi zi zi zi
Drug Administration (FDA)?
zi zi
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C zi
The official name is the name under which a drug is listed by t
zi zi zi zi zi zi zi zi zi zi zi zi zi
he FDA. The brand name, or trademark, is the name given t
zi zi zi zi zi zi zi zi zi zi zi zi
o a drug by its manufacturer. The nonproprietary, or generic,
zi zi zi zi zi zi zi zi zi zi
name is provided by the United States Adopted Names Coun
zi zi zi zi zi zi zi zi zi zi
cil.
DIF: Cognitive Level: Knowledge REF: p. 9 zi zi zi zi
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care Environme
zi zi zi zi zi zi zi zi zi
nt TOP: Nursing Process Step: Assessment
zi z i zi zi zi
CON:
Patient Education zi
2. Which source contains information specific to nutritional supplements?
zi zi zi zi zi zi zi
a. USPDictionary of USAN &International Drug Names zi zi zi zi zi
b. Natural Medicines Comprehensive Database zi zi zi
c. United States Pharmacopoeia/National Formulary(USPNF) zi zi zi
d. DrugInteraction Facts zi zi
ANS: C zi
United States Pharmacopoeia/National Formulary contains information specific to nutritional s
zi zi zi zi zi zi zi zi zi zi
upplements. USP Dictionary of USAN & International Drug Names is a compilation of drug na m
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
es, pronunciation guide, and possible future FDA approved drugs; it does not include nutritio nal
zi zi zi zi zi zi zi zi zi zi zi zi zi zi z
supplements. Natural Medicines Comprehensive Database contains
i zi zi zi zi zi
evidence-
based information on herbal medicines and herbal combination products; it does not include inf o
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
rmation specific to nutritional supplements. Drug Interaction Facts contains comprehensive i nf
zi zi zi zi zi zi zi zi zi zi zi
ormation on drug interaction facts; it does not include nutritional supplements.
zi zi zi zi zi zi zi zi zi zi
DIF: Cognitive Level: Knowledge REF: p. 4 zi zi zi zi
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integ
zi zi zi zi zi zi zi zi
rity
TOP: Nursing Process Step: Assessment
z i zi zi zi CON: Nutrition |Patient Education
zi zi zi
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
zi zi zi zi zi zi zi zi zi zi zi zi zi
a. Drug Facts and Comparisons zi zi zi
,Test Bank ForvClayton’s Basic PharmacologyvforvNurses 19th Edition
zi zi zi zi zi zi 3
b. DrugInteraction Facts zi zi
c. Handbook on Injectable Drugs zi zi zi
d. Martindale—The Complete Drug Reference zi zi zi
ANS: A zi
Drug Facts and Comparisons contains drug monographs that describe all drugs in a th e
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
rapeutic class. Monographs are formatted as tables to allow comparison of similar pro du
zi zi zi zi zi zi zi zi zi zi zi zi zi
cts, brand names, manufacturers, cost indices, and available dosage forms Online ve rsio
zi zi zi zi zi zi zi zi zi zi zi zi
n is available.
zi zi
DIF: Cognitive Level: Knowledge REF: p. 4vTable 1.2 zi zi zi zi zi
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
zizi zi zi zi zi zi zi
TOP: Nursing Process Step: Assessment
z i CON: Safety |Patient Education |Clinical Judgment zi zi zi zi zi zi zi zi zi
4. Which drugreference contains monographs about virtuallyeverysingle-
zi zi zi zi zi zi zi
entitydrug available in the United States and describes therapeutic uses of drugs, including ap pro
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
ved and unapproved uses?
zi zi zi
a. Martindale: The Complete Drug Reference zi zi zi zi
b. AHFS Drug Information zi zi
c. DrugReference zi
d. Drug Facts and Comparisons zi zi zi
ANS: B zi
AHFS Drug Information contains monographs about virtually every single-
zi zi zi zi zi zi zi zi
entity drug available in the United States and describes therapeutic uses ofdrugs, including appr ov
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
ed and unapproved uses.
zi zi zi
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 zi zi zi zi zi zi
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
zizi zi zi zi zi zi zi
TOP: Nursing Process Step: Planning
z i CON: Safety |Patient Education |Clinical Judgment zi zi zi zi zi zi zi zi zi
5. Which online drug reference makes available to healthcare providers and the public a stand ar
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
d, comprehensive, up-to-date look up and downloadable resource about medicines?
zi zi zi zi zi zi zi zi zi
a. American Drug Index zi zi
b. American Hospital Formulary zi zi
c. DailyMed
d. DrugReference zi
ANS: C zi
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
zi zi zi zi zi zi zi zi zi zi zi zi
up-to-
date look up and downloadable resource about medicines. The American Drug Index is not app r
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
opriate for patient use. The American Hospital Formulary is not appropriate for patient use. T
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
he drug reference is not appropriate for patient use.
zi zi zi zi zi zi zi zi
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 zi zi z i zi zi zi zi
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integ
zi zi zi zi zi zi zi zi
rity
TOP: Nursing Process Step: Implementation
zi zi zi zi
CON: Safety |Patient Education |Clinical Judgment
zi zi zi zi zi zi
6. Which legislation authorizes the FDA to determine the safetyof a drug before its marketing?
zi zi zi zi zi zi zi zi zi zi zi zi zi
a. Federal Food, Drug, and Cosmetic Act (1938) zi zi zi zi zi zi
b. Durham HumphreyAmendment (1952) zi zi zi
, Test Bank ForvClayton’s Basic PharmacologyvforvNurses 19th Edition
zi zi zi zi zi zi 4
c. Controlled Substances Act (1970) zi zi zi
d. Kefauver Harris Drug Amendment (1962) zi zi zi zi
ANS: A zi
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safet y
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
of all drugs before marketing. Later amendments and acts helped tighten FDA control and en su
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
revdrug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be use
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
d safely without medical supervision and restricts their sale to prescription by a licensed pr acti
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
tioner. The Controlled Substances Act addresses onlycontrolled substances and their catego rizat
zi zi zi zi zi zi zi zi zi zi zi
ion. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug safety. Drug
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
manufacturers are required to prove to the FDA the effectiveness of their products before market zi zi zi zi zi zi zi zi zi zi zi zi zi zi
ing them. zi
DIF: Cognitive Level: Knowledge zi zi
REF: p. 5 Table l.3 OBJ: 5 zi zi zi zi zi z i
NAT: NCLEX Client Needs Category: Physiological Integrity zi zi zi zi zi zi zi
TOP: Nursing Process Step: Assessment
z i zi zi zi
CON: Safety |Patient Education |Evidence |Health Care Law
zi zi zi zi zi zi zi zi zi
7. Which classification does meperidine (Demerol) fall under?
zi zi zi zi zi zi
a. I
b. II
c. III
d. IV
ANS: B zi
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to se ve
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
re psychological and physical dependence. Schedule I drugs have high potential for abuse and no
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
to moderate physical dependence or high psychological dependence. Schedule IV drugs ha ve lo
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
w potential for abuse. Use may lead to limited physical or psychological dependence.
zi zi zi zi zi zi zi zi zi zi zi zi
DIF: Cognitive Level: Knowledge
z i z i REF: p. 10 zi zi zi zi
OBJ: 2 NAT: NCLEX Client Needs Category: Safe, Effective Car e zi zi zi zi zi zi zi zi zi zi
Environment
zi
TOP: Nursing Process Step: Assessment
z i CON: Patient Education |Addiction |Pain zi zi zi z i z i zi zi zi zi zi
8. Which action would the FDA take to expedite drug development and approval for an outbreak o f s
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
mallpox?
a. List smallpox as a health orphan disease. zi zi zi zi zi zi
b. Omit the preclinical research phase. zi zi zi zi
c. Extend the clinical research phase. zi zi zi zi
d. Fast track the investigational drug. zi zi zi zi
ANS: D zi
Once the Investigational New Drug Application has been approved, the drug can receive high e
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
st priority within the agency, which is called fast tracking. A smallpox outbreak would beco m
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
e a priority concern in the world. Orphan diseases are not researched in a priority manner. Pr ecli
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
nical research is not omitted. Extending any phase of the research would mean a longer tim e to de
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
velop a vaccine. The FDA must ensure that all phases of the preclinical and clinical resea rch pha
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
se have been completed in a safe manner.
zi zi zi zi zi zi zi
DIF: z i Cognitive Level: Knowledge zi zi REF: z i p. 7 zi OBJ: 5 zi
Edition
ByMichelleJ.Willihnganz,SamuelL.Gurevitz,BruceClayton
Complete
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz: Clayton
zi zi zi zi zi zi zi zi zi
’s Basic Pharmacology for Nurses, 19th Edition
zi zi zi zi zi zi
MULTIPLE CHOICE zi
1. Which name identifies a drug listed bythe US Food and
zi zi zi zi zi zi zi zi zi zi
Drug Administration (FDA)?
zi zi
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C zi
The official name is the name under which a drug is listed by t
zi zi zi zi zi zi zi zi zi zi zi zi zi
he FDA. The brand name, or trademark, is the name given t
zi zi zi zi zi zi zi zi zi zi zi zi
o a drug by its manufacturer. The nonproprietary, or generic,
zi zi zi zi zi zi zi zi zi zi
name is provided by the United States Adopted Names Coun
zi zi zi zi zi zi zi zi zi zi
cil.
DIF: Cognitive Level: Knowledge REF: p. 9 zi zi zi zi
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care Environme
zi zi zi zi zi zi zi zi zi
nt TOP: Nursing Process Step: Assessment
zi z i zi zi zi
CON:
Patient Education zi
2. Which source contains information specific to nutritional supplements?
zi zi zi zi zi zi zi
a. USPDictionary of USAN &International Drug Names zi zi zi zi zi
b. Natural Medicines Comprehensive Database zi zi zi
c. United States Pharmacopoeia/National Formulary(USPNF) zi zi zi
d. DrugInteraction Facts zi zi
ANS: C zi
United States Pharmacopoeia/National Formulary contains information specific to nutritional s
zi zi zi zi zi zi zi zi zi zi
upplements. USP Dictionary of USAN & International Drug Names is a compilation of drug na m
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
es, pronunciation guide, and possible future FDA approved drugs; it does not include nutritio nal
zi zi zi zi zi zi zi zi zi zi zi zi zi zi z
supplements. Natural Medicines Comprehensive Database contains
i zi zi zi zi zi
evidence-
based information on herbal medicines and herbal combination products; it does not include inf o
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
rmation specific to nutritional supplements. Drug Interaction Facts contains comprehensive i nf
zi zi zi zi zi zi zi zi zi zi zi
ormation on drug interaction facts; it does not include nutritional supplements.
zi zi zi zi zi zi zi zi zi zi
DIF: Cognitive Level: Knowledge REF: p. 4 zi zi zi zi
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integ
zi zi zi zi zi zi zi zi
rity
TOP: Nursing Process Step: Assessment
z i zi zi zi CON: Nutrition |Patient Education
zi zi zi
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
zi zi zi zi zi zi zi zi zi zi zi zi zi
a. Drug Facts and Comparisons zi zi zi
,Test Bank ForvClayton’s Basic PharmacologyvforvNurses 19th Edition
zi zi zi zi zi zi 3
b. DrugInteraction Facts zi zi
c. Handbook on Injectable Drugs zi zi zi
d. Martindale—The Complete Drug Reference zi zi zi
ANS: A zi
Drug Facts and Comparisons contains drug monographs that describe all drugs in a th e
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
rapeutic class. Monographs are formatted as tables to allow comparison of similar pro du
zi zi zi zi zi zi zi zi zi zi zi zi zi
cts, brand names, manufacturers, cost indices, and available dosage forms Online ve rsio
zi zi zi zi zi zi zi zi zi zi zi zi
n is available.
zi zi
DIF: Cognitive Level: Knowledge REF: p. 4vTable 1.2 zi zi zi zi zi
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
zizi zi zi zi zi zi zi
TOP: Nursing Process Step: Assessment
z i CON: Safety |Patient Education |Clinical Judgment zi zi zi zi zi zi zi zi zi
4. Which drugreference contains monographs about virtuallyeverysingle-
zi zi zi zi zi zi zi
entitydrug available in the United States and describes therapeutic uses of drugs, including ap pro
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
ved and unapproved uses?
zi zi zi
a. Martindale: The Complete Drug Reference zi zi zi zi
b. AHFS Drug Information zi zi
c. DrugReference zi
d. Drug Facts and Comparisons zi zi zi
ANS: B zi
AHFS Drug Information contains monographs about virtually every single-
zi zi zi zi zi zi zi zi
entity drug available in the United States and describes therapeutic uses ofdrugs, including appr ov
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
ed and unapproved uses.
zi zi zi
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 zi zi zi zi zi zi
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
zizi zi zi zi zi zi zi
TOP: Nursing Process Step: Planning
z i CON: Safety |Patient Education |Clinical Judgment zi zi zi zi zi zi zi zi zi
5. Which online drug reference makes available to healthcare providers and the public a stand ar
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
d, comprehensive, up-to-date look up and downloadable resource about medicines?
zi zi zi zi zi zi zi zi zi
a. American Drug Index zi zi
b. American Hospital Formulary zi zi
c. DailyMed
d. DrugReference zi
ANS: C zi
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
zi zi zi zi zi zi zi zi zi zi zi zi
up-to-
date look up and downloadable resource about medicines. The American Drug Index is not app r
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
opriate for patient use. The American Hospital Formulary is not appropriate for patient use. T
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
he drug reference is not appropriate for patient use.
zi zi zi zi zi zi zi zi
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 zi zi z i zi zi zi zi
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integ
zi zi zi zi zi zi zi zi
rity
TOP: Nursing Process Step: Implementation
zi zi zi zi
CON: Safety |Patient Education |Clinical Judgment
zi zi zi zi zi zi
6. Which legislation authorizes the FDA to determine the safetyof a drug before its marketing?
zi zi zi zi zi zi zi zi zi zi zi zi zi
a. Federal Food, Drug, and Cosmetic Act (1938) zi zi zi zi zi zi
b. Durham HumphreyAmendment (1952) zi zi zi
, Test Bank ForvClayton’s Basic PharmacologyvforvNurses 19th Edition
zi zi zi zi zi zi 4
c. Controlled Substances Act (1970) zi zi zi
d. Kefauver Harris Drug Amendment (1962) zi zi zi zi
ANS: A zi
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safet y
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
of all drugs before marketing. Later amendments and acts helped tighten FDA control and en su
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
revdrug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be use
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
d safely without medical supervision and restricts their sale to prescription by a licensed pr acti
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
tioner. The Controlled Substances Act addresses onlycontrolled substances and their catego rizat
zi zi zi zi zi zi zi zi zi zi zi
ion. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug safety. Drug
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
manufacturers are required to prove to the FDA the effectiveness of their products before market zi zi zi zi zi zi zi zi zi zi zi zi zi zi
ing them. zi
DIF: Cognitive Level: Knowledge zi zi
REF: p. 5 Table l.3 OBJ: 5 zi zi zi zi zi z i
NAT: NCLEX Client Needs Category: Physiological Integrity zi zi zi zi zi zi zi
TOP: Nursing Process Step: Assessment
z i zi zi zi
CON: Safety |Patient Education |Evidence |Health Care Law
zi zi zi zi zi zi zi zi zi
7. Which classification does meperidine (Demerol) fall under?
zi zi zi zi zi zi
a. I
b. II
c. III
d. IV
ANS: B zi
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to se ve
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
re psychological and physical dependence. Schedule I drugs have high potential for abuse and no
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
to moderate physical dependence or high psychological dependence. Schedule IV drugs ha ve lo
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
w potential for abuse. Use may lead to limited physical or psychological dependence.
zi zi zi zi zi zi zi zi zi zi zi zi
DIF: Cognitive Level: Knowledge
z i z i REF: p. 10 zi zi zi zi
OBJ: 2 NAT: NCLEX Client Needs Category: Safe, Effective Car e zi zi zi zi zi zi zi zi zi zi
Environment
zi
TOP: Nursing Process Step: Assessment
z i CON: Patient Education |Addiction |Pain zi zi zi z i z i zi zi zi zi zi
8. Which action would the FDA take to expedite drug development and approval for an outbreak o f s
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
mallpox?
a. List smallpox as a health orphan disease. zi zi zi zi zi zi
b. Omit the preclinical research phase. zi zi zi zi
c. Extend the clinical research phase. zi zi zi zi
d. Fast track the investigational drug. zi zi zi zi
ANS: D zi
Once the Investigational New Drug Application has been approved, the drug can receive high e
zi zi zi zi zi zi zi zi zi zi zi zi zi zi
st priority within the agency, which is called fast tracking. A smallpox outbreak would beco m
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
e a priority concern in the world. Orphan diseases are not researched in a priority manner. Pr ecli
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
nical research is not omitted. Extending any phase of the research would mean a longer tim e to de
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
velop a vaccine. The FDA must ensure that all phases of the preclinical and clinical resea rch pha
zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi zi
se have been completed in a safe manner.
zi zi zi zi zi zi zi
DIF: z i Cognitive Level: Knowledge zi zi REF: z i p. 7 zi OBJ: 5 zi
