MICR 3230 Midterm | UPDATED Questions with 100% Verified Answers

MICR 3230 Midterm | UPDATED Questions with 100% Verified
Answers

Question:
Herd immunity

Answer:
Vaccination/protection of a critical mass of people


Question:
Humoral immunity

Answer:
Combats pathogens via antibodies produced by B cells
Active vs. passive


Question:
Cell-mediated immunity

Answer:
T cells that eradicate pathogens, self-cells, or aid other cells


Question:
BCR and TCR generated by

Answer:
Random gene segment rearrangements


Question:
4 categories of pathogens

Answer:
1. Viruses
2. Bacteria
3. Fungi
4. Parasites


Question:
PRRs bind to

, Answer:
PAMPs and DAMPs
PRRs always expressed


Question:
Clonal selection

Answer:
B and T cells go through generation of diversity and deletion if not activated by their
specific antigen
If activated, the cell undergoes proliferation and produces a large number of clones


Question:
Tolerance

Answer:
Self vs non-self discrimination


Question:
Innate vs adaptive system - major components

Answer:
Innate - phagocytes, barriers, PRRs
Adaptive - T and B lymphocytes, antigen-specific receptors, Abs


Question:
Primary lymphoid organs

Answer:
Bone marrow and thymus
Where immune cells mature from immature precursors


Question:
Secondary lymphoid organs

Answer:
Spleen, lymph nodes, MALT/GALT
Where mature lymphocytes encounter antigen and begin differentiation

, Question:
Common myeloid progenitor gives rise to

Answer:
RBCs
Granulocytes (eosinophil, basophil, neutrophil, mast cell)
Monocytes (DCs and macrophages)
DCs
Platelets


Question:
Common lymphoid progenitor gives rise to

Answer:
DCs
T cells (Th and Tc)
B cells
ILCs


Question:
Neutrophil molecules

Answer:
Proteases
Antimicrobial proteins
Histamine


Question:
Eosinophil molecules

Answer:
Cationic proteins
Cytokines
Chemokines


Question:
Basophil molecules