MICR 3230 Midterm Exam University of Guelph | UPDATED Questions
with 100% Verified Answers
Question:
What is immunity?
Answer:
The state of protection against foreign pathogens or substances (antigens)
Question:
How do you generate immunity without disease?
Answer:
Immunization
Question:
What does immunization do?
Answer:
Prepares the immune system for eradication of the antigen
Question:
What is herd immunity?
Answer:
Vaccination/protection of a critical mass of people
Question:
What is humoral immunity?
Answer:
Combats pathogens via antibodies
Question:
What are antibodies produced by?
Answer:
B cells
,Question:
2 types of humoral immunity:
Answer:
Passive & active
Question:
What is cell-mediated immunity mediated by?
Answer:
T lymphocytes
Question:
How does cell-mediated immunity work?
Answer:
Eradicates pathogens, clear infected self-cells, aid other cells in immunity
Question:
Humoral & cell-mediated immunity rely on:
Answer:
Surface receptors of B and T cells
Question:
Receptors are randomly generated by:
Answer:
Gene segment rearrangements in the cells
Question:
B cells that encounter antigen produce:
Answer:
Specific antibodies
Question:
T cells:
Answer:
,Bind antigens/specific peptides presented by APCs
Question:
General gist of humoral immunity:
Answer:
BCR binds antigen
Antigen internalized
B cell produces antibodies
Question:
General gist of cell-mediated:
Answer:
TCR binds antigen
T cell produces cytokines
OR
TCR binds antigen
Antigen internalized
Infected cells recognized by APCs & lysed
Question:
4 major categories of pathogens:
Answer:
Viruses
Bacteria
Fungi
Parasites
Question:
What is pathogen recognition?
Answer:
An interaction b/w foreign organism & recognition molecule expressed by host
Question:
Ligands include:
, Answer:
Whole pathogens
Antigenic fragments
Products secreted by foreign organisms
Question:
The immune response is:
Answer:
An extra-/intracellular cascade of events leading to the labeling & destruction of
pathogen after ligand binding
Question:
Cells that recognize & kill/engulf pathogen labelled:
Answer:
CELLULAR immunity
Question:
Soluble proteins for labeling & destruction of invaders
labelled:
Answer:
HUMORAL immunity
Question:
Immune responses rely on:
Answer:
Recognition molecules
Question:
Recognition molecules are:
Answer:
Encoded in DNA - always expressed - PRRs
PRRs bind to PAMPs
Randomly generated
with 100% Verified Answers
Question:
What is immunity?
Answer:
The state of protection against foreign pathogens or substances (antigens)
Question:
How do you generate immunity without disease?
Answer:
Immunization
Question:
What does immunization do?
Answer:
Prepares the immune system for eradication of the antigen
Question:
What is herd immunity?
Answer:
Vaccination/protection of a critical mass of people
Question:
What is humoral immunity?
Answer:
Combats pathogens via antibodies
Question:
What are antibodies produced by?
Answer:
B cells
,Question:
2 types of humoral immunity:
Answer:
Passive & active
Question:
What is cell-mediated immunity mediated by?
Answer:
T lymphocytes
Question:
How does cell-mediated immunity work?
Answer:
Eradicates pathogens, clear infected self-cells, aid other cells in immunity
Question:
Humoral & cell-mediated immunity rely on:
Answer:
Surface receptors of B and T cells
Question:
Receptors are randomly generated by:
Answer:
Gene segment rearrangements in the cells
Question:
B cells that encounter antigen produce:
Answer:
Specific antibodies
Question:
T cells:
Answer:
,Bind antigens/specific peptides presented by APCs
Question:
General gist of humoral immunity:
Answer:
BCR binds antigen
Antigen internalized
B cell produces antibodies
Question:
General gist of cell-mediated:
Answer:
TCR binds antigen
T cell produces cytokines
OR
TCR binds antigen
Antigen internalized
Infected cells recognized by APCs & lysed
Question:
4 major categories of pathogens:
Answer:
Viruses
Bacteria
Fungi
Parasites
Question:
What is pathogen recognition?
Answer:
An interaction b/w foreign organism & recognition molecule expressed by host
Question:
Ligands include:
, Answer:
Whole pathogens
Antigenic fragments
Products secreted by foreign organisms
Question:
The immune response is:
Answer:
An extra-/intracellular cascade of events leading to the labeling & destruction of
pathogen after ligand binding
Question:
Cells that recognize & kill/engulf pathogen labelled:
Answer:
CELLULAR immunity
Question:
Soluble proteins for labeling & destruction of invaders
labelled:
Answer:
HUMORAL immunity
Question:
Immune responses rely on:
Answer:
Recognition molecules
Question:
Recognition molecules are:
Answer:
Encoded in DNA - always expressed - PRRs
PRRs bind to PAMPs
Randomly generated
