BIO 340 Holechek Exam Questions and
Correct Answers
Question 1
A species has n=4 chromosomes. Genes on the same chromosome have a minimum
recombination recombination rate of:
Correct Answer
0%
Question 2
What disease is caused by a recessive mutation in the
PAH gene
Correct Answer
Phenylketonuria (PKU)
Question 3
Gene interaction occurs when two or more genes affect the same phenotype. What
type of interaction is this?
Correct Answer
epistatic
Question 4
In an example of ____ ____ red flowers are bred with white flowers and produce pink
flowers.
Correct Answer
Incomplete dominance
Page 1 of 53
,Question 5
Does non random mating affect genotypic ratios?
Correct Answer
yes
Question 6
the presence of one crossover prevents other crossovers from occurring nearby
Correct Answer
Interference
Question 7
method of discovering whether two mutations are in the same or separate genes
Correct Answer
Complementation test
Question 8
1.11
Correct Answer
Bristle number: Number of individuals:
11
24
37
4 31
5 56
6 17
74
The table shows the distribution of the number of bristles in a Drosophila
population indicating how many individuals in the population have those particular
number of bristles. Calculate the variance for the number of bristles in the entire
population.
Page 2 of 53
,Question 9
The strength of linkage tells us the ____ between two genes
Correct Answer
distance
Question 10
Genes are located on the same chromosome in different species. Order of gene is not
known.
Correct Answer
conserved synteny
Question 11
Dominant gene interaction has what ratio in their offspring?
Correct Answer
9:6:1
Question 12
**Exam Question** Wild type blue-eyed Mary has blue flowers. Two genes control
the pathway that makes the blue pigment: The product of gene W turns a white
precursor into magenta pigment. The product of gene M turns the magenta pigment
into blue pigment. Each gene has a recessive loss-of-function allele: w and m,
respectively. A dihybrid (WwMm) is self-pollinated. What proportion of the offspring
will be magenta?
Correct Answer
3/16
Question 13
The relative fitness values of three genotypes are: wAA = 1.0, wAa = 1.0, and waa =
0.7. What is the predicted equilibrium allele frequency if the rate of mutation of A to a
is 2 x 10^-5?
Correct Answer
q hat = 0.008 and p hat = 0.992
Page 3 of 53
, Question 14
if you know what
the expected is based on Mendel results
or
genetic analyses performed on a specific locus you would use what equation for
degrees of freedom
Correct Answer
n-1
Question 15
Recombination frequency ____ true map distance
Correct Answer
underestimates
Question 16
If black and white true-breeding mice are mated and the result is all gray offspring,
what inheritance pattern would this be indicative of?
Correct Answer
Incomplete dominance
Question 17
If your population is diploid and has 20 members, how many alleles are present in
that particular gene pool?
Correct Answer
40
Question 18
Perform a dihybrid testcross and determine if offspring have 1:1:1:1 phenotypic ratio.
In order to do this what would be considered the tester genotype? If you know your
tester is aabb what should be the other parental genotype?
Correct Answer
AaBb
Page 4 of 53
Correct Answers
Question 1
A species has n=4 chromosomes. Genes on the same chromosome have a minimum
recombination recombination rate of:
Correct Answer
0%
Question 2
What disease is caused by a recessive mutation in the
PAH gene
Correct Answer
Phenylketonuria (PKU)
Question 3
Gene interaction occurs when two or more genes affect the same phenotype. What
type of interaction is this?
Correct Answer
epistatic
Question 4
In an example of ____ ____ red flowers are bred with white flowers and produce pink
flowers.
Correct Answer
Incomplete dominance
Page 1 of 53
,Question 5
Does non random mating affect genotypic ratios?
Correct Answer
yes
Question 6
the presence of one crossover prevents other crossovers from occurring nearby
Correct Answer
Interference
Question 7
method of discovering whether two mutations are in the same or separate genes
Correct Answer
Complementation test
Question 8
1.11
Correct Answer
Bristle number: Number of individuals:
11
24
37
4 31
5 56
6 17
74
The table shows the distribution of the number of bristles in a Drosophila
population indicating how many individuals in the population have those particular
number of bristles. Calculate the variance for the number of bristles in the entire
population.
Page 2 of 53
,Question 9
The strength of linkage tells us the ____ between two genes
Correct Answer
distance
Question 10
Genes are located on the same chromosome in different species. Order of gene is not
known.
Correct Answer
conserved synteny
Question 11
Dominant gene interaction has what ratio in their offspring?
Correct Answer
9:6:1
Question 12
**Exam Question** Wild type blue-eyed Mary has blue flowers. Two genes control
the pathway that makes the blue pigment: The product of gene W turns a white
precursor into magenta pigment. The product of gene M turns the magenta pigment
into blue pigment. Each gene has a recessive loss-of-function allele: w and m,
respectively. A dihybrid (WwMm) is self-pollinated. What proportion of the offspring
will be magenta?
Correct Answer
3/16
Question 13
The relative fitness values of three genotypes are: wAA = 1.0, wAa = 1.0, and waa =
0.7. What is the predicted equilibrium allele frequency if the rate of mutation of A to a
is 2 x 10^-5?
Correct Answer
q hat = 0.008 and p hat = 0.992
Page 3 of 53
, Question 14
if you know what
the expected is based on Mendel results
or
genetic analyses performed on a specific locus you would use what equation for
degrees of freedom
Correct Answer
n-1
Question 15
Recombination frequency ____ true map distance
Correct Answer
underestimates
Question 16
If black and white true-breeding mice are mated and the result is all gray offspring,
what inheritance pattern would this be indicative of?
Correct Answer
Incomplete dominance
Question 17
If your population is diploid and has 20 members, how many alleles are present in
that particular gene pool?
Correct Answer
40
Question 18
Perform a dihybrid testcross and determine if offspring have 1:1:1:1 phenotypic ratio.
In order to do this what would be considered the tester genotype? If you know your
tester is aabb what should be the other parental genotype?
Correct Answer
AaBb
Page 4 of 53
