Advanced Pharmacology -
NP actual questions with
100% correct answers +
detailed explanations
Antiepileptic drugs
i Antimicrobials - Tetracyclines,
. fluoroquinolones
| Vitamin A in large doses
Highest Teratogenic medications
i Some anticoags
Hormonal meds such as DES
. Non-medication examples -
i Alcohol & cocaine
. Increased absorption
Transdermal absorption in Infants have thin skin - higher
neonates and infants . blood flow
: Increased risk for toxicity
Intramuscular absorption in Neonate - Slow and erratic first
neonates and infants : few days of life
, Infants - Increased absorption
. due to increased blood flow
. Increased absorption of drugs
. absorbed in stomach
Decreased absorption in drugs
Oral absorption in neonates and \ absorbed in intestines
infants Delayed gastric emptying
Increased absorption of acid-
: labile drugs - Low gastric acidity
. for 24 hr after birth
Metabolism is markedly faster in
children under age
What effects do the below meds
have on children:; Glucocorticoids - Growth
| supression
Glucocorticoids
. Tetracyclines - Discolored teeth
Tetracyclines
. Sulfonamides - Kernicterus
Sulfonamides
Considerations when selecting Cost
medication treatment:
Guidelines
- Availability
Interactions
Side Effects
- Allergies
Hepatic & renal function
Need for monitoring
NP actual questions with
100% correct answers +
detailed explanations
Antiepileptic drugs
i Antimicrobials - Tetracyclines,
. fluoroquinolones
| Vitamin A in large doses
Highest Teratogenic medications
i Some anticoags
Hormonal meds such as DES
. Non-medication examples -
i Alcohol & cocaine
. Increased absorption
Transdermal absorption in Infants have thin skin - higher
neonates and infants . blood flow
: Increased risk for toxicity
Intramuscular absorption in Neonate - Slow and erratic first
neonates and infants : few days of life
, Infants - Increased absorption
. due to increased blood flow
. Increased absorption of drugs
. absorbed in stomach
Decreased absorption in drugs
Oral absorption in neonates and \ absorbed in intestines
infants Delayed gastric emptying
Increased absorption of acid-
: labile drugs - Low gastric acidity
. for 24 hr after birth
Metabolism is markedly faster in
children under age
What effects do the below meds
have on children:; Glucocorticoids - Growth
| supression
Glucocorticoids
. Tetracyclines - Discolored teeth
Tetracyclines
. Sulfonamides - Kernicterus
Sulfonamides
Considerations when selecting Cost
medication treatment:
Guidelines
- Availability
Interactions
Side Effects
- Allergies
Hepatic & renal function
Need for monitoring
