NSG5240 Midterm Review
actual questions with 100%
correct answers + detailed
explanations
. Requires energy (ATP)
Active transport
Moves low — high concentration
No energy required
passive diffusion Moves from high — low
i concentration
i Uses carrier proteins
facilitated diffusion
No energy required
. The movement of a drug from its
What is drug absorption? . site of administration into
: systemic circulation.
Where does oral drug absorption . :
. Small intestine.
primarily occur?
, What is the absorption phase for
Immediate (no absorption
intravenous (V) drug
. phase).
administration?
Where does intramuscular (IM)
or subcutaneous (SubQ) drug Muscle or tissue.
absorption occur?
Where does inhaled drug
E Lungs.
absorption occur?
Rate of dissolution
Surface area
Factor affecting Drug Absorption Blood flow
Lipid Solubility
pH Partitioning
Renal (primary)
Excretion sites Non renal (breast milk, bile,
. lungs, sweat, and saliva)
. Glomerular filtration
Steps in Renal excretion . Passive tubular reabsorption
. Active tubular reabsorption
Organs responsible for drug : Main organ: Liver
metabolism . Others: kidneys, lungs, intestines
actual questions with 100%
correct answers + detailed
explanations
. Requires energy (ATP)
Active transport
Moves low — high concentration
No energy required
passive diffusion Moves from high — low
i concentration
i Uses carrier proteins
facilitated diffusion
No energy required
. The movement of a drug from its
What is drug absorption? . site of administration into
: systemic circulation.
Where does oral drug absorption . :
. Small intestine.
primarily occur?
, What is the absorption phase for
Immediate (no absorption
intravenous (V) drug
. phase).
administration?
Where does intramuscular (IM)
or subcutaneous (SubQ) drug Muscle or tissue.
absorption occur?
Where does inhaled drug
E Lungs.
absorption occur?
Rate of dissolution
Surface area
Factor affecting Drug Absorption Blood flow
Lipid Solubility
pH Partitioning
Renal (primary)
Excretion sites Non renal (breast milk, bile,
. lungs, sweat, and saliva)
. Glomerular filtration
Steps in Renal excretion . Passive tubular reabsorption
. Active tubular reabsorption
Organs responsible for drug : Main organ: Liver
metabolism . Others: kidneys, lungs, intestines
