ONS CHEMOTHERAPY IMMUNOTHERAPY
CERTIFICATE CERTIFICATION
EVALUATION COMPLETE QUESTIONS AND
VERIFIED SOLUTIONS
●● Define adjuvant therapy
Answer: Additional cancer treatment given after the primary treatment to
lower the risk that the cancer reoccur
●● 3 subcategories of alkylating agents:
Answer: 1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas
●● Common alkylating agents:
Answer: Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
●● Common platinum-based agents:
Answer: Cisplatin (Platinol)
,Carboplatin (Paraplatin)
●● What is unique about nitrosoureas agents?
Answer: Able to cross the blood-brain barrier; can be effective in
treating some brain tumors
●● Common nitrosoureas agents:
Answer: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
●● Hypersensitivity can occur with late doses of:
Answer: Carboplatin
●● These agents are typically categorized as highly emetogenic:
Answer: 1. Alkylating agents
2. Nitrosoureas
●● Pre-administration labs for alkylating agents and nitrosoureas:
Answer: BUN
Creatinine
CBC w/ diff
, ●● What is the medication Mesna used for?
Answer: Bladder protectant with administration of cyclophosphamide or
ifosfamide
●● Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment
Answer: Oxaliplatin
●● How do antimetabolites function?
Answer: By blocking DNA and RNA growth by interfering with
enzymes needed for normal cell metabolism
●● Antimetabolites work in the ___ phase.
Answer: S
●● Common side effects of antimetabolites:
Answer: Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
●● Common antimetabolite drugs:
CERTIFICATE CERTIFICATION
EVALUATION COMPLETE QUESTIONS AND
VERIFIED SOLUTIONS
●● Define adjuvant therapy
Answer: Additional cancer treatment given after the primary treatment to
lower the risk that the cancer reoccur
●● 3 subcategories of alkylating agents:
Answer: 1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas
●● Common alkylating agents:
Answer: Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
●● Common platinum-based agents:
Answer: Cisplatin (Platinol)
,Carboplatin (Paraplatin)
●● What is unique about nitrosoureas agents?
Answer: Able to cross the blood-brain barrier; can be effective in
treating some brain tumors
●● Common nitrosoureas agents:
Answer: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
●● Hypersensitivity can occur with late doses of:
Answer: Carboplatin
●● These agents are typically categorized as highly emetogenic:
Answer: 1. Alkylating agents
2. Nitrosoureas
●● Pre-administration labs for alkylating agents and nitrosoureas:
Answer: BUN
Creatinine
CBC w/ diff
, ●● What is the medication Mesna used for?
Answer: Bladder protectant with administration of cyclophosphamide or
ifosfamide
●● Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment
Answer: Oxaliplatin
●● How do antimetabolites function?
Answer: By blocking DNA and RNA growth by interfering with
enzymes needed for normal cell metabolism
●● Antimetabolites work in the ___ phase.
Answer: S
●● Common side effects of antimetabolites:
Answer: Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
●● Common antimetabolite drugs:
