D027 Advanced Pathopharmacological
Foundations Exam Questions with Verified
Correct Answers
What organ does cystic fibrosis affect?
Affects the pancreas causing secretions into the lungs
What is Klinefelter syndrome?
An extra X chromosome for males so example XXY causing female-like qualities
What is Turner Syndrome?
females. missing or deformed x chromosome. right hemisphere dysfunction, hearing loss, ear
infection, language and articulation disorders, visual spatial and attentional problems
What is beta thalassemia?
a condition in which the synthesis of the beta-globin chains is decreased or absent. Causes low
hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia?
Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia).
Directly toxic to lymphoid tissues Selective estrogen receptor modulators (SERM) - for
hormone receptor positive and advanced breast cancer. (Tomaxafin - reduces risk and
recurrence risk)
Glucocorticoids
What is the normal ejection fraction?
55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved?
Preserved
, What are symptoms of left sided heart failure?
Think PULMONARY. JVD, FVO, rails, S3 murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure?
Think peripheral vascular. Lower extremity edema, abdominal distension.
What is the gold standard lab test for heart failure?
BNP. Heart failure is a result greater than 100
What heart disease is worse with exertion?
Ischemic heart disease because the demand requirements are higher.
What should you assess before giving Digoxin?
Apical pulse
How should Warfarin be started?
Start initial dose at half to monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to
hyperinflation
Emphysema
What causes excess mucus production and smooth muscle hypertrophy?
Bronchitis
What is a chronic inflammatory obstruction of bronchi?
Asthma, Triggers cause mucus to clog bronchial tubes.
What causes an overbite and buffalo hump?
Endocrine disorder called acromegaly (overproduction of growth hormone)
What causes Addison's disease?
Decreased glucocorticoid (due to autoimmune destruction of adrenal cortex)
What causes Cushing's syndrome?
excess cortisol
What causes Grave's disease?
Foundations Exam Questions with Verified
Correct Answers
What organ does cystic fibrosis affect?
Affects the pancreas causing secretions into the lungs
What is Klinefelter syndrome?
An extra X chromosome for males so example XXY causing female-like qualities
What is Turner Syndrome?
females. missing or deformed x chromosome. right hemisphere dysfunction, hearing loss, ear
infection, language and articulation disorders, visual spatial and attentional problems
What is beta thalassemia?
a condition in which the synthesis of the beta-globin chains is decreased or absent. Causes low
hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia?
Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia).
Directly toxic to lymphoid tissues Selective estrogen receptor modulators (SERM) - for
hormone receptor positive and advanced breast cancer. (Tomaxafin - reduces risk and
recurrence risk)
Glucocorticoids
What is the normal ejection fraction?
55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved?
Preserved
, What are symptoms of left sided heart failure?
Think PULMONARY. JVD, FVO, rails, S3 murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure?
Think peripheral vascular. Lower extremity edema, abdominal distension.
What is the gold standard lab test for heart failure?
BNP. Heart failure is a result greater than 100
What heart disease is worse with exertion?
Ischemic heart disease because the demand requirements are higher.
What should you assess before giving Digoxin?
Apical pulse
How should Warfarin be started?
Start initial dose at half to monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to
hyperinflation
Emphysema
What causes excess mucus production and smooth muscle hypertrophy?
Bronchitis
What is a chronic inflammatory obstruction of bronchi?
Asthma, Triggers cause mucus to clog bronchial tubes.
What causes an overbite and buffalo hump?
Endocrine disorder called acromegaly (overproduction of growth hormone)
What causes Addison's disease?
Decreased glucocorticoid (due to autoimmune destruction of adrenal cortex)
What causes Cushing's syndrome?
excess cortisol
What causes Grave's disease?
