NBME CBSE Comprehensive Questions and Answers Study Guide – Medical Exam Preparation

Questions
edical Exam
NBME_CBSE
and
Preparation
Answers
–Study
(3
Comprehensive
files
Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
(NBME_CBSE for Comprehensive
– Medical
Questions
Exam and
Preparation
Answers
Questions Study
(3 files
and Answers Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!
Study forforMedical
Guide Exam
Medical Exam Preparation
Preparation 2026) (3 files merged).pdf!@@@




NBME/CBSE –
Comprehensive
Questions and
Answers Study
Guide for
Medical Exam
Preparation



Questions
edical Exam
NBME_CBSE
and
Preparation
Answers
–Study
(3
Comprehensive
files
Guide 3/16/2026, 6:19:45 PM
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
for Medical
Questions
Exam
and
Preparation
Answers Study
(3 files
Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!
for Medical Exam Preparation (3 files merged).pdf!@@@

,Questions
edical Exam
NBME_CBSE
and
Preparation
Answers
–Study
(3
Comprehensive
files
Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
(NBME_CBSE for Comprehensive
– Medical
Questions
Exam and
Preparation
Answers
Questions Study
(3 files
and Answers Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!
Study forforMedical
Guide Exam
Medical Exam Preparation
Preparation 2026) (3 files merged).pdf!@@@




Neurology & Reflexes

Q: What does a positive Babinski sign indicate?

A: There is an UMN lesion; hyperreflexia +3; dorsiflexion with stroke of the plantar foot.


Q: ACA lesion symptoms?

A: Contralateral lower limb deficits, behavioral changes, urinary incontinence.


Q: Abduction of shoulder: which muscles act at different ranges?

A:


● Initial: Supraspinatus

● Below horizontal: Deltoid

● Above horizontal: Trapezius + Serratus anterior


Q: Adduction of shoulder: which muscles?

A: Teres Minor (axillary n), Subscapular (subscapular n)




Metabolism & Starvation

Q: Energy source after >3 days of starvation?

A: Adipose → Ketones (Leucine, Lysine).


Q: Energy source 1–3 days starvation?

A: FFA via hormone-sensitive lipase


● Stimulated by epinephrine

● Gluconeogenesis supported by cortisol (OAA → PEP)




Questions
edical Exam
NBME_CBSE
and
Preparation
Answers
–Study
(3
Comprehensive
files
Guide 3/16/2026, 6:19:45 PM
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
for Medical
Questions
Exam
and
Preparation
Answers Study
(3 files
Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!
for Medical Exam Preparation (3 files merged).pdf!@@@

,Questions
edical Exam
NBME_CBSE
and
Preparation
Answers
–Study
(3
Comprehensive
files
Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
(NBME_CBSE for Comprehensive
– Medical
Questions
Exam and
Preparation
Answers
Questions Study
(3 files
and Answers Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!
Study forforMedical
Guide Exam
Medical Exam Preparation
Preparation 2026) (3 files merged).pdf!@@@




Q: Abetalipoproteinemia: features?

A: Foamy cytoplasm at villi tips, NO APO-B → no VLDL or chylomicrons




Endocrinology

Q: 1-α-hydroxylase in macrophages does what?

A: PTH-independent conversion of Calcifediol → Calcitriol (active Vit D) → hypercalcemia


Q: Hyperaldosteronism (primary) lab findings?

A:


● Increased mineralocorticoids (Zona glomerulosa)

● ↓ Renin → HTN

● ↓ K → paresthesia

● ↑ HCO3


Q: Secondary hyperaldosteronism?

A: JC renin-secreting tumor → ↑ Renin and Aldo


Q: Hyperparathyroidism labs?

A:


● Primary: ↑ PTH, ↑ Ca, ↓ PO4 → “stones, thrones, groans, psych overtones”

● Secondary: ↑ PTH due to ↑ PO4, ↓ Ca → low D synthesis


Q: Addison’s disease labs?

A: Primary adrenal insufficiency


● ACTH does not increase cortisol

● ↓ Na, ↑ K, ↑ Cl




Questions
edical Exam
NBME_CBSE
and
Preparation
Answers
–Study
(3
Comprehensive
files
Guide 3/16/2026, 6:19:45 PM
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
for Medical
Questions
Exam
and
Preparation
Answers Study
(3 files
Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!
for Medical Exam Preparation (3 files merged).pdf!@@@

,Questions
edical Exam
NBME_CBSE
and
Preparation
Answers
–Study
(3
Comprehensive
files
Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
(NBME_CBSE for Comprehensive
– Medical
Questions
Exam and
Preparation
Answers
Questions Study
(3 files
and Answers Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!
Study forforMedical
Guide Exam
Medical Exam Preparation
Preparation 2026) (3 files merged).pdf!@@@




● Non-anion gap metabolic acidosis

● Weight loss, hyperpigmentation, hypotension


Q: Adrenal adenoma?

A: Atrophy of uninvolved Zona fasciculata & reticularis


● ACTH independent


Q: Adrenal cortex layers (outer → inner)?

A:


● Glomerulosa → Aldosterone

● Fasciculata → Cortisol

● Reticularis → Androgen




Cardiology & Hematology

Q: Abciximab MOA & AE?

A: GP IIb/IIIa inhibitor → no platelet aggregation


Q: Adenosine MOA & AE?

A: Blocks AV node conduction → used for PSVT


● AE: flushing, chest burning, hypotension


Q: AAA features?

A: Chronic transmural inflammation, pulsating central abdominal mass




Pulmonology



Questions
edical Exam
NBME_CBSE
and
Preparation
Answers
–Study
(3
Comprehensive
files
Guide 3/16/2026, 6:19:45 PM
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
for Medical
Questions
Exam
and
Preparation
Answers Study
(3 files
Guide
merged).pdf!@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1!!!!
for Medical Exam Preparation (3 files merged).pdf!@@@