NURS 5334 ADVANCED PHARMACOLOGY
TEST 2 COMPREHENSIVE REVIEW PAPER
2026 UPDATED QUESTIONS WITH
SOLUTIONS GRADED A+
⩥ trimethoprim.
Answer: MOA = inhibits dihydrofolate reductase -> supress DNA,
RNA, protein synthesis
uses = acute and uncomplicated UTIs
AE = hematologic effects, hyperK, use in pregnancy and lactation
⩥ Trimethoprim/Sulfamethoxazole.
Answer: MOA = inhibits bacterial folic acid synthesis powerfullly
use = UTI, OM, bronchitis, pneumonia, GI infection
AE = NV, rash, hyperK, stevens johnson, birth defects in first trimester
⩥ upper UTI.
Answer: kidneys
, acute pyelo
acute bacterial prostatitis
⩥ lower UTI.
Answer: bladder & urethra
acute cystitis
acute urethral syndrome
⩥ organism that causes 80% uncomplicated community acquired UTIs.
Answer: E coli
⩥ organism that causes most hosptial aquired UTIs.
Answer: klebsiella
proteus
enterbacter
pseudomonas
staph
enterococci
e coli
TEST 2 COMPREHENSIVE REVIEW PAPER
2026 UPDATED QUESTIONS WITH
SOLUTIONS GRADED A+
⩥ trimethoprim.
Answer: MOA = inhibits dihydrofolate reductase -> supress DNA,
RNA, protein synthesis
uses = acute and uncomplicated UTIs
AE = hematologic effects, hyperK, use in pregnancy and lactation
⩥ Trimethoprim/Sulfamethoxazole.
Answer: MOA = inhibits bacterial folic acid synthesis powerfullly
use = UTI, OM, bronchitis, pneumonia, GI infection
AE = NV, rash, hyperK, stevens johnson, birth defects in first trimester
⩥ upper UTI.
Answer: kidneys
, acute pyelo
acute bacterial prostatitis
⩥ lower UTI.
Answer: bladder & urethra
acute cystitis
acute urethral syndrome
⩥ organism that causes 80% uncomplicated community acquired UTIs.
Answer: E coli
⩥ organism that causes most hosptial aquired UTIs.
Answer: klebsiella
proteus
enterbacter
pseudomonas
staph
enterococci
e coli
