NURS 5334 ADVANCED PHARMACOLOGY
TEST 2 ACTUAL TEST PAPER 2026
DETAILED QUESTIONS WITH SOLUTION
GUIDE GRADED A+
⩥ Osteoporosis tx in men?
Answer: 5 drugs:
Alendronate [Fosamax]
Risedronate [Actonel]
Zoledronate [Reclast]
Teriparatide [Forteo]
Denosumab [Prolia]
⩥ Difference between creams, ointments, & gels?
Answer: Ointment: thick, greasy preparations; oil or petroleum jelly
base w/little water
Creams: Oil & water emulsion; more oil than water or vice versa
Gels: transparent preps; cellulose w/a water or alcohol base
⩥ Which skin dx has highest absorption?
,Answer: Ointments have highest medication absorption
⩥ Which skin dx is best for oily skin?
Answer: Gels
⩥ Which skin dx best for inflammed skin?
Answer: Creams
⩥ Topical glucocorticoids adverse effects (local)
Answer: Thinning of the skin
Stretch marks
Purpura
Telangiectasia
Hypertrichosis
Possible systemic toxicity
⩥ Topical glucocorticoids adverse effects (systemic)
Answer: More likely with higher doses and long-term therapy
Growth retardation in children
Adrenal suppression
⩥ How are topical glucocorticoids administered?
,Answer: Apply in a thin film and gently rub into the skin
Do not use occlusive bandages (or tight-fitting diapers and plastic pants)
⩥ What are keratolytic agents?
Answer: Promote shedding of horny layer of skin
Tx conditions of overgrowth or abnormal thickening of skin
Dx: salicylic acid, sulfur, benzoyl peroxide
⩥ Nondrug tx of acne?
Answer: Cleanse w/ nonirritant soap
Avoid vigorous scrubing or use of abrasions
Avoid oil-based makeup/moisturizers
Comedo extraction
Dermabrasion
⩥ Benzoyl peroxide
Answer: First line dx for mild-moderate acne
An antibiotic and keratolytic
Suppresses growth of P. acnes
Causes drying & peeling of skin
⩥ Acne antibiotics (topical)
, Answer: Clindamycin
Erythromycin
*avoid monotherapy, causes resistance> combine w/ benzoyl peroxide
⩥ Acne antibiotics (oral)
Answer: Tetracycline antibx
Isotretinoin
Hormonal agents
⩥ Dapsone & acne
Answer: Used for tx of leprosy
W/acne tx> modest decrease in inflammation & # of lesions
AE: oiliness, peeling, dryness, erythema
⩥ Topical drugs for acne
Answer: Retinoids
Azelaic acid
⩥ Retinoids
Answer: For acne tx
Reduce inflammation & improve penetration of other agents
TEST 2 ACTUAL TEST PAPER 2026
DETAILED QUESTIONS WITH SOLUTION
GUIDE GRADED A+
⩥ Osteoporosis tx in men?
Answer: 5 drugs:
Alendronate [Fosamax]
Risedronate [Actonel]
Zoledronate [Reclast]
Teriparatide [Forteo]
Denosumab [Prolia]
⩥ Difference between creams, ointments, & gels?
Answer: Ointment: thick, greasy preparations; oil or petroleum jelly
base w/little water
Creams: Oil & water emulsion; more oil than water or vice versa
Gels: transparent preps; cellulose w/a water or alcohol base
⩥ Which skin dx has highest absorption?
,Answer: Ointments have highest medication absorption
⩥ Which skin dx is best for oily skin?
Answer: Gels
⩥ Which skin dx best for inflammed skin?
Answer: Creams
⩥ Topical glucocorticoids adverse effects (local)
Answer: Thinning of the skin
Stretch marks
Purpura
Telangiectasia
Hypertrichosis
Possible systemic toxicity
⩥ Topical glucocorticoids adverse effects (systemic)
Answer: More likely with higher doses and long-term therapy
Growth retardation in children
Adrenal suppression
⩥ How are topical glucocorticoids administered?
,Answer: Apply in a thin film and gently rub into the skin
Do not use occlusive bandages (or tight-fitting diapers and plastic pants)
⩥ What are keratolytic agents?
Answer: Promote shedding of horny layer of skin
Tx conditions of overgrowth or abnormal thickening of skin
Dx: salicylic acid, sulfur, benzoyl peroxide
⩥ Nondrug tx of acne?
Answer: Cleanse w/ nonirritant soap
Avoid vigorous scrubing or use of abrasions
Avoid oil-based makeup/moisturizers
Comedo extraction
Dermabrasion
⩥ Benzoyl peroxide
Answer: First line dx for mild-moderate acne
An antibiotic and keratolytic
Suppresses growth of P. acnes
Causes drying & peeling of skin
⩥ Acne antibiotics (topical)
, Answer: Clindamycin
Erythromycin
*avoid monotherapy, causes resistance> combine w/ benzoyl peroxide
⩥ Acne antibiotics (oral)
Answer: Tetracycline antibx
Isotretinoin
Hormonal agents
⩥ Dapsone & acne
Answer: Used for tx of leprosy
W/acne tx> modest decrease in inflammation & # of lesions
AE: oiliness, peeling, dryness, erythema
⩥ Topical drugs for acne
Answer: Retinoids
Azelaic acid
⩥ Retinoids
Answer: For acne tx
Reduce inflammation & improve penetration of other agents
