Barkley Preventive Care Practice Exam 200
Original Practice Questions with Detailed
Rationales
Table of Contents
1. Health Promotion and Disease Prevention (Questions 1–40)
2. Immunizations (Questions 41–80)
3. Cancer Screening (Questions 81–120)
4. Behavioral Counseling and Lifestyle Interventions
(Questions 121–155)
5. Special Populations and Risk-Based Screening (Questions
156–185)
6. Chemoprophylaxis and Preventive Medications (Questions
186–200)
7. Answer Key Summary
8. Exam Preparation Tips
Section 1: Health Promotion and Disease Prevention
(Questions 1–40)
1. A 45-year-old male with a history of hypertension
presents with a blood pressure of 148/92 mmHg on two
separate occasions. He has no other comorbidities.
According to current guidelines, what is the most
appropriate initial management?
A. Begin antihypertensive medication immediately
B. Recommend lifestyle modification and recheck in 3–6 months
,C. Refer to cardiology for further evaluation
D. Order an echocardiogram to assess for target organ damage
Correct Answer: B. Recommend lifestyle modification and
recheck in 3–6 months
Rationale: For patients with Stage 1 hypertension (130–
139/80–89) who have no other comorbidities, lifestyle
modification (diet, exercise, sodium reduction) is
recommended for 3–6 months before initiating
pharmacotherapy. Medication is started if BP remains
elevated after this period.
2. A 55-year-old woman of average risk asks when she can
stop screening mammography. According to the USPSTF,
what is the recommended upper age limit for breast cancer
screening in average-risk women?
A. 65 years
B. 70 years
C. 74 years
D. 80 years
Correct Answer: C. 74 years
Rationale: The USPSTF recommends screening
mammography every 2 years for women aged 40–74. The
recommendation stops at age 74 because evidence for
screening beyond this age is limited.
3. A 50-year-old man at average risk asks about colorectal
cancer screening. According to the USPSTF, when should
colorectal cancer screening begin?
A. Age 40
B. Age 45
,C. Age 50
D. Age 55
Correct Answer: B. Age 45
Rationale: The USPSTF recommends screening for
colorectal cancer in all adults aged 45–75. Screening
options include colonoscopy every 10 years, annual FIT, CT
colonography every 5 years, or flexible sigmoidoscopy
every 5 years.
4. A 65-year-old woman with no chronic conditions asks
which screening tests are recommended for her age.
According to the USPSTF, which of the following is
recommended for this patient?
A. Bone mineral density testing
B. Annual PSA screening
C. Annual CA-125 screening
D. Annual chest X-ray
Correct Answer: A. Bone mineral density testing
Rationale: The USPSTF recommends screening for
osteoporosis with bone mineral density testing in all
women aged 65 and older. PSA screening is not
recommended for women. CA-125 is not recommended for
ovarian cancer screening in average-risk women. Chest X-
ray is not recommended for lung cancer screening.
5. A 55-year-old woman of average risk asks when she can
stop cervical cancer screening. According to the USPSTF, at
what age can cervical cancer screening be discontinued in
women who have had adequate prior screening?
A. 60 years
B. 65 years
, C. 70 years
D. 75 years
Correct Answer: B. 65 years
Rationale: The USPSTF recommends discontinuing cervical
cancer screening in women aged 65 and older who have
had adequate prior negative screening (three consecutive
negative cytology tests or two consecutive negative HPV
co-tests within the past 10 years).
6. A 45-year-old woman presents for a routine visit.
According to the USPSTF, what is the recommended
screening interval for cervical cancer in women aged 30–65?
A. Pap smear every year
B. Pap smear every 3 years
C. Pap smear with HPV co-testing every 5 years
D. HPV testing alone every 10 years
Correct Answer: C. Pap smear with HPV co-testing every 5
years
Rationale: For women aged 30–65, the preferred screening
strategy is Pap smear with HPV co-testing every 5 years.
Pap smear alone every 3 years is also acceptable.
7. A 50-year-old man with a 20 pack-year smoking history
who currently smokes asks about lung cancer screening.
According to the USPSTF, what is the recommended
screening modality?
A. Chest X-ray every year
B. Low-dose CT scan every year
C. Sputum cytology every year
D. No screening recommended
Original Practice Questions with Detailed
Rationales
Table of Contents
1. Health Promotion and Disease Prevention (Questions 1–40)
2. Immunizations (Questions 41–80)
3. Cancer Screening (Questions 81–120)
4. Behavioral Counseling and Lifestyle Interventions
(Questions 121–155)
5. Special Populations and Risk-Based Screening (Questions
156–185)
6. Chemoprophylaxis and Preventive Medications (Questions
186–200)
7. Answer Key Summary
8. Exam Preparation Tips
Section 1: Health Promotion and Disease Prevention
(Questions 1–40)
1. A 45-year-old male with a history of hypertension
presents with a blood pressure of 148/92 mmHg on two
separate occasions. He has no other comorbidities.
According to current guidelines, what is the most
appropriate initial management?
A. Begin antihypertensive medication immediately
B. Recommend lifestyle modification and recheck in 3–6 months
,C. Refer to cardiology for further evaluation
D. Order an echocardiogram to assess for target organ damage
Correct Answer: B. Recommend lifestyle modification and
recheck in 3–6 months
Rationale: For patients with Stage 1 hypertension (130–
139/80–89) who have no other comorbidities, lifestyle
modification (diet, exercise, sodium reduction) is
recommended for 3–6 months before initiating
pharmacotherapy. Medication is started if BP remains
elevated after this period.
2. A 55-year-old woman of average risk asks when she can
stop screening mammography. According to the USPSTF,
what is the recommended upper age limit for breast cancer
screening in average-risk women?
A. 65 years
B. 70 years
C. 74 years
D. 80 years
Correct Answer: C. 74 years
Rationale: The USPSTF recommends screening
mammography every 2 years for women aged 40–74. The
recommendation stops at age 74 because evidence for
screening beyond this age is limited.
3. A 50-year-old man at average risk asks about colorectal
cancer screening. According to the USPSTF, when should
colorectal cancer screening begin?
A. Age 40
B. Age 45
,C. Age 50
D. Age 55
Correct Answer: B. Age 45
Rationale: The USPSTF recommends screening for
colorectal cancer in all adults aged 45–75. Screening
options include colonoscopy every 10 years, annual FIT, CT
colonography every 5 years, or flexible sigmoidoscopy
every 5 years.
4. A 65-year-old woman with no chronic conditions asks
which screening tests are recommended for her age.
According to the USPSTF, which of the following is
recommended for this patient?
A. Bone mineral density testing
B. Annual PSA screening
C. Annual CA-125 screening
D. Annual chest X-ray
Correct Answer: A. Bone mineral density testing
Rationale: The USPSTF recommends screening for
osteoporosis with bone mineral density testing in all
women aged 65 and older. PSA screening is not
recommended for women. CA-125 is not recommended for
ovarian cancer screening in average-risk women. Chest X-
ray is not recommended for lung cancer screening.
5. A 55-year-old woman of average risk asks when she can
stop cervical cancer screening. According to the USPSTF, at
what age can cervical cancer screening be discontinued in
women who have had adequate prior screening?
A. 60 years
B. 65 years
, C. 70 years
D. 75 years
Correct Answer: B. 65 years
Rationale: The USPSTF recommends discontinuing cervical
cancer screening in women aged 65 and older who have
had adequate prior negative screening (three consecutive
negative cytology tests or two consecutive negative HPV
co-tests within the past 10 years).
6. A 45-year-old woman presents for a routine visit.
According to the USPSTF, what is the recommended
screening interval for cervical cancer in women aged 30–65?
A. Pap smear every year
B. Pap smear every 3 years
C. Pap smear with HPV co-testing every 5 years
D. HPV testing alone every 10 years
Correct Answer: C. Pap smear with HPV co-testing every 5
years
Rationale: For women aged 30–65, the preferred screening
strategy is Pap smear with HPV co-testing every 5 years.
Pap smear alone every 3 years is also acceptable.
7. A 50-year-old man with a 20 pack-year smoking history
who currently smokes asks about lung cancer screening.
According to the USPSTF, what is the recommended
screening modality?
A. Chest X-ray every year
B. Low-dose CT scan every year
C. Sputum cytology every year
D. No screening recommended
