WGU D027 VERIFIED STUDY GUIDE
Autosomal Dominant - Answers - 1 parent has, 50% change of child having
Autosomal Recessive - Answers - Both parents are carriers, 25% change of child
having, 50% chance child is a carrier.
Cystic Fibrosis - Answers - affects pancreas causing secretions in lungs
21st Trisomy - Answers - Down Syndrome
Klinefelter Syndrome (XXY) - Answers - male has extra X, female like qualities
Turner Syndrome - Answers - Missing X in females
Alpha Thalassemia - Answers - inherited blood disorder; mild to severe anemia
Beta Thallasemia - Answers - low hemoglobin; contraindicated medication ferrous
sulfate
Prevalence Risk - Answers - proportion of the population affected at a certain time
Incidence rate - Answers - number of new cases divided by population
Innate immunity - Answers - inflammation; increased vascular permeability
B&T lymphocytes - Answers - immune response
primary malignant tumor - Answers - lack of organization of cells
glucocorticoids - Answers - used in combination with other agent to treat lymphoid
tissue (leukemia). glucocorticoids are directly toxic to lymphoid tissues.
Selective estrogen receptor modulators (SERM) - Answers - for hormone receptor
positive and advanced breast cancer. (Tamoxifin reduces risk and recurrence risk)
Heart failure - Answers - impairment of the ventricle to fill with or eject blood; heart
cannot meet metabolic need of the body.
CHF - Answers - heart cannot keep up with metabolic needs; volume overload in
pulmonary area
, Left Ventricular Dysfunction - Answers - reduced ejection fraction; ventricle having issue
ejecting blood.
normal ejection fraction - Answers - 55 - 60 % (blood pumped out with each heartbeat)
Ejection fraction of 50% - reduced or preserved? - Answers - preserved
Diastolic CHF - Answers - preserved ejection fraction, problem is with filling
Systolic CHF - Answers - reduced ejection fraction, problem is with ejecting
Left sided CHF - Answers - pulmonary (JVD, fluid volume overload, rails, S-3 murmurs)
** #1 cause of Right sided CHF
BNP - Answers - gold standard lab test to diagnose CHF
Echocardiogram - Answers - Diagnostic tool, evaluates heart structure and function
At Risk for HF - Stage A - Answers - no structural heart disease or symptoms of heart
failure
Stage A HF co-morbidities - Answers - htn, atherosclerotic disease, diabetes, metabolic
syndrome, patients using cardiotoxins with family history
Therapy goals of stage A HF - Answers - treat htn, encourage smoking cessation,
encourage regular exercise, treat lipid disorders, discourage alcohol intake/drug use,
control metabolic syndrome
Meds: ACEI or Angiotensin II RB for vascular disease or diabetes (avapro, losartan,
benicar, diovan, etc)
At Risk for HF - Stage B - Answers - structural heart disease but no symptoms of heart
failure
Stage B HF co-morbidities - Answers - previous MI, LV remodeling with LV hypertrophy
and low EF, asymptomatic valvular disease
Therapy goals of Stage B HF - Answers - Meds: ACEI or ARB, Beta-blockers,
inplantable defibrillators
Stage C heart failure - Answers - structural heart disease with prior or current symptoms
of HF
Presentation of Stage C HF - Answers - known structural heart disease and shortness
of breath and fatigue, reduced exercise tolerance
Autosomal Dominant - Answers - 1 parent has, 50% change of child having
Autosomal Recessive - Answers - Both parents are carriers, 25% change of child
having, 50% chance child is a carrier.
Cystic Fibrosis - Answers - affects pancreas causing secretions in lungs
21st Trisomy - Answers - Down Syndrome
Klinefelter Syndrome (XXY) - Answers - male has extra X, female like qualities
Turner Syndrome - Answers - Missing X in females
Alpha Thalassemia - Answers - inherited blood disorder; mild to severe anemia
Beta Thallasemia - Answers - low hemoglobin; contraindicated medication ferrous
sulfate
Prevalence Risk - Answers - proportion of the population affected at a certain time
Incidence rate - Answers - number of new cases divided by population
Innate immunity - Answers - inflammation; increased vascular permeability
B&T lymphocytes - Answers - immune response
primary malignant tumor - Answers - lack of organization of cells
glucocorticoids - Answers - used in combination with other agent to treat lymphoid
tissue (leukemia). glucocorticoids are directly toxic to lymphoid tissues.
Selective estrogen receptor modulators (SERM) - Answers - for hormone receptor
positive and advanced breast cancer. (Tamoxifin reduces risk and recurrence risk)
Heart failure - Answers - impairment of the ventricle to fill with or eject blood; heart
cannot meet metabolic need of the body.
CHF - Answers - heart cannot keep up with metabolic needs; volume overload in
pulmonary area
, Left Ventricular Dysfunction - Answers - reduced ejection fraction; ventricle having issue
ejecting blood.
normal ejection fraction - Answers - 55 - 60 % (blood pumped out with each heartbeat)
Ejection fraction of 50% - reduced or preserved? - Answers - preserved
Diastolic CHF - Answers - preserved ejection fraction, problem is with filling
Systolic CHF - Answers - reduced ejection fraction, problem is with ejecting
Left sided CHF - Answers - pulmonary (JVD, fluid volume overload, rails, S-3 murmurs)
** #1 cause of Right sided CHF
BNP - Answers - gold standard lab test to diagnose CHF
Echocardiogram - Answers - Diagnostic tool, evaluates heart structure and function
At Risk for HF - Stage A - Answers - no structural heart disease or symptoms of heart
failure
Stage A HF co-morbidities - Answers - htn, atherosclerotic disease, diabetes, metabolic
syndrome, patients using cardiotoxins with family history
Therapy goals of stage A HF - Answers - treat htn, encourage smoking cessation,
encourage regular exercise, treat lipid disorders, discourage alcohol intake/drug use,
control metabolic syndrome
Meds: ACEI or Angiotensin II RB for vascular disease or diabetes (avapro, losartan,
benicar, diovan, etc)
At Risk for HF - Stage B - Answers - structural heart disease but no symptoms of heart
failure
Stage B HF co-morbidities - Answers - previous MI, LV remodeling with LV hypertrophy
and low EF, asymptomatic valvular disease
Therapy goals of Stage B HF - Answers - Meds: ACEI or ARB, Beta-blockers,
inplantable defibrillators
Stage C heart failure - Answers - structural heart disease with prior or current symptoms
of HF
Presentation of Stage C HF - Answers - known structural heart disease and shortness
of breath and fatigue, reduced exercise tolerance
