Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and
Physician Assistants (2nd Edition Rosenthal Test Bank)
Lehne’s Pharmacotherapeutics
for Advanced Practice Nurses and
Physician Assistants (2nd Edition
Rosenthal Test Bank) Exam Study
Guide – Practice Questions with
Verified Answers. GRADED A+.
Latest 2026/2027 Update
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 23. The
nurse is preparing to administer penicillin G intramuscularly to a child. The
child's parents ask why the drug cannot be given in an oral liquid form. What is
the nurse's reply?
d. "This drug would be inactivated by enzymes in the stomach."
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 24. Which
statement about food and drug interactions is true?
d. Some foods can inhibit CYP isoenzymes and alter drug metabolism.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 25. A nurse
is teaching a patient about a drug that induces P-glycoprotein. The nurse will
explain that this drug may cause which effect on other drugs?
b. Decreased elimination through the kidneys
,Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and
Physician Assistants (2nd Edition Rosenthal Test Bank)
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 26. A patient
claims to get better effects with a tablet of Brand X of a drug than with a tablet
of Brand Y of the same drug. Both brands contain the same amount of the
active ingredient. What does the nurse know to be most likely?
c. Tablets can differ in composition and can have differing rates of
disintegration and dissolution, which can alter the drug's effects in the body.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 27. Two
nurses are discussing theories of drug-receptor interaction. Which statements
are true regarding the affinity of a drug and its receptor?
b. Affinity refers to the strength of the attraction between a drug and its
receptor.
c. Drugs with high affinity are strongly attracted to their receptors.
e. The affinity of a drug for its receptors is reflected in its potency.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 28. A patient
receives a drug that has a narrow therapeutic range. The nurse administering
this medication will expect to do what?
c. Monitor plasma drug levels.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 29. What
occurs when a drug binds to a receptor in the body?
b. It increases or decreases the activity of that receptor.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 30. A patient
is receiving intravenous gentamicin. A serum drug test reveals toxic levels. The
dosing is correct, and this medication has been tolerated by this patient in the
past. Which could be a probable cause of the test result?
c. The patient is taking another medication that binds to serum albumin.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 31. A patient
reports becoming "immune" to a medication because it no longer works to
alleviate symptoms. The nurse recognizes that this decreased effectiveness is
likely caused by:
c. Desensitization of receptor sites by continual exposure to the drug.
,Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and
Physician Assistants (2nd Edition Rosenthal Test Bank)
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 32. A patient
who is taking morphine for pain asks the nurse how a pain medication can also
cause constipation. What does the nurse know about morphine?
d. It is selective to receptors that regulate more than one body process.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 33. The
nurse is administering morning medications. The nurse gives a patient multiple
medications, two of which compete for plasma albumin receptor sites. As a
result of this concurrent administration, the nurse can anticipate that what
might occur?
a. Binding of one or both agents will be reduced.
b. Plasma levels of free drug will rise.
d. The increase in free drug will intensify effects.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 34. When
administering medications to infants, it is important to remember which of the
following?
b. Immaturity of renal function in infancy causes infants to excrete drugs less
efficiently. <br> c. Infants have immature livers, which slows drug metabolism.
<br> d. Infants are more sensitive to medications that act on the central
nervous system (CNS).
Ch 1 Prescriptive Authority 2. Which factors increase the need for APRNs to
have full prescriptive authority?
a. More patients will have access to health care.
Ch 1 Prescriptive Authority 3. Which factors could be attributed to limited
prescriptive authority for APRNs? Select all that apply.
a. Inaccessibility of patient care
b. Higher health care costs
Ch 1 Prescriptive Authority 4. Which aspects support the APRN's provision for
full prescriptive authority? Select all that apply
, Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and
Physician Assistants (2nd Edition Rosenthal Test Bank)
a. Clinical education includes prescription of medications and disease
processes.
c. National examinations provide validation of the APRN's ability to provide safe
care.
d. Licensure ensures compliance with health care and safety standards.
Ch 1 Prescriptive Authority 5. Which aspects support the APRN's provision for
full prescriptive authority? Select all that apply.
a. Clinical education includes prescription of medications and disease
processes.
c. National examinations provide validation of the APRN's ability to provide safe
care.
d. Licensure ensures compliance with health care and safety standards.
Ch 1 Prescriptive Authority 6. A family nurse practitioner practicing in Maine is
hired at a practice across state lines in Virginia. Which aspect of practice may
change for the APRN?
a. The APRN will have less prescriptive authority in the new position.
Ch 2 Rational Drug Selection and Prescription Writing 7. How can collaboration
with a pharmacist improve positive outcomes for patients? Select all that apply.
b. Pharmacists have additional information on drug interactions.
c. The pharmacist can suggest adequate medication dosing.
d. Pharmacists have firsthand knowledge of the facility formulary.
Ch 2 Rational Drug Selection and Prescription Writing 8. A patient presents with
delirium tremens requiring Ativan administration. The provider of care is not in
the facility. Which action by the nurse is most appropriate?
a. Obtain a telephone order.
Ch 2 Rational Drug Selection and Prescription Writing 9. A patient with chronic
pain calls the provider's office to request a refill on their oxycontin. Which
action is most appropriate?
b. Schedule an appointment with the patient.
Physician Assistants (2nd Edition Rosenthal Test Bank)
Lehne’s Pharmacotherapeutics
for Advanced Practice Nurses and
Physician Assistants (2nd Edition
Rosenthal Test Bank) Exam Study
Guide – Practice Questions with
Verified Answers. GRADED A+.
Latest 2026/2027 Update
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 23. The
nurse is preparing to administer penicillin G intramuscularly to a child. The
child's parents ask why the drug cannot be given in an oral liquid form. What is
the nurse's reply?
d. "This drug would be inactivated by enzymes in the stomach."
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 24. Which
statement about food and drug interactions is true?
d. Some foods can inhibit CYP isoenzymes and alter drug metabolism.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 25. A nurse
is teaching a patient about a drug that induces P-glycoprotein. The nurse will
explain that this drug may cause which effect on other drugs?
b. Decreased elimination through the kidneys
,Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and
Physician Assistants (2nd Edition Rosenthal Test Bank)
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 26. A patient
claims to get better effects with a tablet of Brand X of a drug than with a tablet
of Brand Y of the same drug. Both brands contain the same amount of the
active ingredient. What does the nurse know to be most likely?
c. Tablets can differ in composition and can have differing rates of
disintegration and dissolution, which can alter the drug's effects in the body.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 27. Two
nurses are discussing theories of drug-receptor interaction. Which statements
are true regarding the affinity of a drug and its receptor?
b. Affinity refers to the strength of the attraction between a drug and its
receptor.
c. Drugs with high affinity are strongly attracted to their receptors.
e. The affinity of a drug for its receptors is reflected in its potency.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 28. A patient
receives a drug that has a narrow therapeutic range. The nurse administering
this medication will expect to do what?
c. Monitor plasma drug levels.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 29. What
occurs when a drug binds to a receptor in the body?
b. It increases or decreases the activity of that receptor.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 30. A patient
is receiving intravenous gentamicin. A serum drug test reveals toxic levels. The
dosing is correct, and this medication has been tolerated by this patient in the
past. Which could be a probable cause of the test result?
c. The patient is taking another medication that binds to serum albumin.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 31. A patient
reports becoming "immune" to a medication because it no longer works to
alleviate symptoms. The nurse recognizes that this decreased effectiveness is
likely caused by:
c. Desensitization of receptor sites by continual exposure to the drug.
,Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and
Physician Assistants (2nd Edition Rosenthal Test Bank)
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 32. A patient
who is taking morphine for pain asks the nurse how a pain medication can also
cause constipation. What does the nurse know about morphine?
d. It is selective to receptors that regulate more than one body process.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 33. The
nurse is administering morning medications. The nurse gives a patient multiple
medications, two of which compete for plasma albumin receptor sites. As a
result of this concurrent administration, the nurse can anticipate that what
might occur?
a. Binding of one or both agents will be reduced.
b. Plasma levels of free drug will rise.
d. The increase in free drug will intensify effects.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 34. When
administering medications to infants, it is important to remember which of the
following?
b. Immaturity of renal function in infancy causes infants to excrete drugs less
efficiently. <br> c. Infants have immature livers, which slows drug metabolism.
<br> d. Infants are more sensitive to medications that act on the central
nervous system (CNS).
Ch 1 Prescriptive Authority 2. Which factors increase the need for APRNs to
have full prescriptive authority?
a. More patients will have access to health care.
Ch 1 Prescriptive Authority 3. Which factors could be attributed to limited
prescriptive authority for APRNs? Select all that apply.
a. Inaccessibility of patient care
b. Higher health care costs
Ch 1 Prescriptive Authority 4. Which aspects support the APRN's provision for
full prescriptive authority? Select all that apply
, Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and
Physician Assistants (2nd Edition Rosenthal Test Bank)
a. Clinical education includes prescription of medications and disease
processes.
c. National examinations provide validation of the APRN's ability to provide safe
care.
d. Licensure ensures compliance with health care and safety standards.
Ch 1 Prescriptive Authority 5. Which aspects support the APRN's provision for
full prescriptive authority? Select all that apply.
a. Clinical education includes prescription of medications and disease
processes.
c. National examinations provide validation of the APRN's ability to provide safe
care.
d. Licensure ensures compliance with health care and safety standards.
Ch 1 Prescriptive Authority 6. A family nurse practitioner practicing in Maine is
hired at a practice across state lines in Virginia. Which aspect of practice may
change for the APRN?
a. The APRN will have less prescriptive authority in the new position.
Ch 2 Rational Drug Selection and Prescription Writing 7. How can collaboration
with a pharmacist improve positive outcomes for patients? Select all that apply.
b. Pharmacists have additional information on drug interactions.
c. The pharmacist can suggest adequate medication dosing.
d. Pharmacists have firsthand knowledge of the facility formulary.
Ch 2 Rational Drug Selection and Prescription Writing 8. A patient presents with
delirium tremens requiring Ativan administration. The provider of care is not in
the facility. Which action by the nurse is most appropriate?
a. Obtain a telephone order.
Ch 2 Rational Drug Selection and Prescription Writing 9. A patient with chronic
pain calls the provider's office to request a refill on their oxycontin. Which
action is most appropriate?
b. Schedule an appointment with the patient.
