Galen College of Nursing
Actual Exam Questions and Answers Practice Questions
A+ GRADED
Welcome to NSG 3850 Exam 4 Practice Examination. This comprehensive test bank covers
essential concepts in hepatic and endocrine disorders including cirrhosis complications,
hepatitis, Wilson's disease, steatohepatitis, and endocrine physiology. The exam consists of 250
multiple-choice questions designed to assess your understanding of pathophysiology, clinical
manifestations, diagnostic procedures, and nursing interventions for hepatic and endocrine
conditions. Each question includes the correct answer and a brief rationale to enhance your
learning experience and prepare you for success on the actual examination.
Domains Covered:
1. Hepatic Disorders - Cirrhosis and Complications (Questions 1-40)
2. Esophageal Varices - Pathophysiology and Management (Questions 41-65)
3. Hepatic Encephalopathy - Pathophysiology and Management (Questions 66-90)
4. Cerebral Edema and Mannitol Therapy (Questions 91-105)
5. Hepatitis - Types and Autoimmune Hepatitis (Questions 106-140)
6. Wilson's Disease - Pathophysiology and Management (Questions 141-165)
7. Steatohepatitis - Pathophysiology and Management (Questions 166-190)
8. Endocrine System - Steroid Hormones and Lipid-Soluble Hormones (Questions 191-220)
9. Endocrine Disorders - Primary vs Secondary Disorders (Questions 221-250)
QUESTION 1
A patient with a history of alcoholism presents with hematemesis and profound anemia.
The expected diagnosis is:
A) Ascites
B) Cerebral edema
C) Hepatic encephalopathy
D) Gastroesophageal varices
Answer: D) Gastroesophageal varices
Rationale: Patients with a history of alcoholism often develop portal hypertension leading
to gastroesophageal varices. Hematemesis (vomiting blood) and profound anemia are
,classic presentations of bleeding esophageal varices, a life-threatening complication of
cirrhosis.
QUESTION 2
A patient admitted with bleeding related to esophageal varices could be expected to
receive a continuous intravenous infusion of:
A) Glucose
B) Octreotide acetate
C) Anticoagulants
D) Proton pump inhibitors
Answer: B) Octreotide acetate
Rationale: Octreotide acetate is a synthetic analog of somatostatin that reduces portal
blood pressure and splanchnic blood flow, making it effective in controlling bleeding from
esophageal varices. It is administered as a continuous IV infusion.
QUESTION 3
A patient being treated for hepatic encephalopathy could be expected to receive a(n)
______ diet.
A) Low-protein
B) High-protein
C) High-sodium
D) Unrestricted
Answer: A) Low-protein
Rationale: Hepatic encephalopathy is treated with a low-protein diet to reduce the
production of ammonia, which is a byproduct of protein metabolism. Ammonia is normally
metabolized by the liver, but in liver failure, it accumulates and causes neurological
symptoms.
QUESTION 4
An infusion of mannitol would be prescribed to treat:
A) Varices
B) Encephalopathy
,C) Peritonitis
D) Cerebral edema
Answer: D) Cerebral edema
Rationale: Mannitol is an osmotic diuretic used to reduce intracranial pressure in patients
with cerebral edema. It draws fluid from brain tissue into the vascular space, reducing
cerebral swelling.
QUESTION 5
Hepatitis with the presence of autoantibodies and positive antinuclear antibodies (ANA) is:
A) Hepatitis D
B) Autoimmune hepatitis
C) Hepatitis A
D) Hepatitis B
Answer: B) Autoimmune hepatitis
Rationale: Autoimmune hepatitis is characterized by the presence of autoantibodies,
including antinuclear antibodies (ANA), anti-smooth muscle antibodies (ASMA), and
elevated immunoglobulins (especially IgG). It is a chronic inflammatory liver disease of
unknown cause.
QUESTION 6
______ disease is a rare autosomal recessive disorder in which excessive amounts of
copper accumulate in the liver.
A) Kayser-Fleischer
B) Wilson
C) Reye
D) Byler
Answer: B) Wilson
Rationale: Wilson's disease is a rare autosomal recessive disorder characterized by
defective copper transport, leading to accumulation of copper in the liver, brain, kidneys,
and cornea. Kayser-Fleischer rings (copper deposits in the cornea) are a classic finding.
, QUESTION 7
Steatohepatitis is caused by an accumulation of:
A) Fat
B) Bile
C) Acetaminophen
D) Ferritin
Answer: A) Fat
Rationale: Steatohepatitis is liver inflammation caused by the accumulation of fat
(steatosis) in the liver. It can be alcoholic or non-alcoholic (NASH) and may progress to
cirrhosis if left untreated.
QUESTION 8
Which statement is true about steroid hormones?
A) Transported in a free state in the bloodstream
B) Bound to receptors on the plasma membranes of target cells
C) Diffused through cell membranes to activate intracellular receptors
D) Activated by second-messenger cascades within the target cells
Answer: C) Diffused through cell membranes to activate intracellular receptors
Rationale: Steroid hormones are lipid-soluble and can diffuse through the cell membrane
to bind to intracellular receptors (cytoplasmic or nuclear). This hormone-receptor complex
then acts as a transcription factor to regulate gene expression.
QUESTION 9
An example of a lipid-soluble hormone is:
A) Catecholamine
B) Thyroid hormone
C) Peptide hormone
D) Pituitary hormone
Answer: B) Thyroid hormone
Rationale: Thyroid hormones (T3 and T4) are lipid-soluble hormones derived from tyrosine
and iodine. They can cross cell membranes and bind to intracellular receptors to exert
their effects on metabolism and development.