RNC NIC COMPREHENSIVE COURSE REVIEW
◉ rbcs usage.
Answer: used to treat anemia and hemorrhage and to improve tissue
oxygenation associated with loss of oxygen carrying capacity
◉ rbs must be used within.
Answer: 4 hours of preparation; in neonates should last at least 2 to
3 hours to prevent overload
◉ neonates generally transfused with how much rbs.
Answer: 10 ml/kg
◉ how much should we expect hgb to increase after transfusion.
Answer: 1 g/dl
crit by 3%
◉ platelet usage.
Answer: used for active bleeding related to thrombocytopenia or
platelet dysfunction or as prophylaxis without active bleeding
present
,◉ plasma usage.
Answer: bleeding related to a deficiency of multiple coagulation
factors, reversal of warfarin effects, or treatment of coagulopathies
◉ cryoprecipitate usage.
Answer: treatment of defective or absent plasma proteins.
Cryoprecipitate is the precipitate that remains after the thawing
process of plasma and consists of enriched factor VIII, von
Willebrand factor, fibrinogen, and factor XIII. Cryoprecipitate is used
in patients with factor XIII deficiency, such as hemophilia A and B, or
disease-related deficiencies (e.g., disseminated intravascular
coagulation [DIC]), or von Willebrand disease.
◉ Benefits of leukocyte reduction.
Answer: ecrease the frequency of recurrent febrile nonhemolytic
transfusion reaction, which is typically manifested by a temperature
elevation of 1°C (1.8°F) or more occurring during or within 4 hours
of transfusion.1 Leukocyte-reduced components also have been
shown to reduce the risk of transfusion-transmitted
cytomegalovirus (CMV) and to reduce the incidence of human
leukocyte antigen (HLA) alloimmunization.
◉ Irradiated blood components prevent.
Answer: propagation of T lymphocytes, which is the immediate
cause of transfusion-associated graft-versus-host disease (GVHD)
, ◉ Washing blood and blood products removes.
Answer: unwanted plasma proteins, including antibodies. Washing
is indicated when these products are suspected to predispose the
patient to significant transfusion reactions.
◉ why are units of blood divided into aliquots.
Answer: reduce exposure to multiple donors
◉ preparation of blood transfusion.
Answer: type and screen
gather supplies
verify informed consent
pretransfusion meds?
obtain blood component when ready
◉ blood transfusion order needs to include.
Answer: type of blood
special preparation
quantity
duration
◉ rbcs usage.
Answer: used to treat anemia and hemorrhage and to improve tissue
oxygenation associated with loss of oxygen carrying capacity
◉ rbs must be used within.
Answer: 4 hours of preparation; in neonates should last at least 2 to
3 hours to prevent overload
◉ neonates generally transfused with how much rbs.
Answer: 10 ml/kg
◉ how much should we expect hgb to increase after transfusion.
Answer: 1 g/dl
crit by 3%
◉ platelet usage.
Answer: used for active bleeding related to thrombocytopenia or
platelet dysfunction or as prophylaxis without active bleeding
present
,◉ plasma usage.
Answer: bleeding related to a deficiency of multiple coagulation
factors, reversal of warfarin effects, or treatment of coagulopathies
◉ cryoprecipitate usage.
Answer: treatment of defective or absent plasma proteins.
Cryoprecipitate is the precipitate that remains after the thawing
process of plasma and consists of enriched factor VIII, von
Willebrand factor, fibrinogen, and factor XIII. Cryoprecipitate is used
in patients with factor XIII deficiency, such as hemophilia A and B, or
disease-related deficiencies (e.g., disseminated intravascular
coagulation [DIC]), or von Willebrand disease.
◉ Benefits of leukocyte reduction.
Answer: ecrease the frequency of recurrent febrile nonhemolytic
transfusion reaction, which is typically manifested by a temperature
elevation of 1°C (1.8°F) or more occurring during or within 4 hours
of transfusion.1 Leukocyte-reduced components also have been
shown to reduce the risk of transfusion-transmitted
cytomegalovirus (CMV) and to reduce the incidence of human
leukocyte antigen (HLA) alloimmunization.
◉ Irradiated blood components prevent.
Answer: propagation of T lymphocytes, which is the immediate
cause of transfusion-associated graft-versus-host disease (GVHD)
, ◉ Washing blood and blood products removes.
Answer: unwanted plasma proteins, including antibodies. Washing
is indicated when these products are suspected to predispose the
patient to significant transfusion reactions.
◉ why are units of blood divided into aliquots.
Answer: reduce exposure to multiple donors
◉ preparation of blood transfusion.
Answer: type and screen
gather supplies
verify informed consent
pretransfusion meds?
obtain blood component when ready
◉ blood transfusion order needs to include.
Answer: type of blood
special preparation
quantity
duration