WGU C785 Final Exam with Complete Solutions
correct answer
A mutation in the beta-hemoglobin gene,
which results in the replacement of the The original amino acid in a healthy patient is glutamate, which
amino acid glutamate in position 6 with the is negatively charged. The mutated amino acid is valine, which
amino acid valine, leads to the development is non-polar. Valine is causing sickle cell anemia. The best
of sickle cell anemia. The structures of amino acid to replace valine so that the patient is healthy
glutamate and valine are shown below. again would be the one most like glutamate, so any negatively
charged amino acid.
If the beta hemoglobin gene in a patient
with sickle-cell anemia were to be edited so
that the valine in position 6 was replaced
with a different amino acid, which
replacement for valine would be expected
to have the best clinical outcome, in theory,
for the patient? (Assume the valine can
potentially be replaced with any amino acid
other than glutamate.)
correct answer
Secondary, tertiary, and quaternary levels of
protein structure can all be impacted by Placement of the protein in a solution with a low pH
exposing a protein to which treatment?
Changes in pH affect hydrogen bonds and ionic bonds.
Change of a hydrophobic amino acid to a Hydrogen bonds in the backbone of amino acids occur in
different hydrophobic amino acid secondary structure, and both hydrogen bonds and ionic
bonds occur in the side chains of amino acids in tertiary
Addition of a reducing agent structure.
Placement of the protein in a solution with a
low pH
Increase in the concentration of the protein
in solution
correct answer
An increase in beta-pleated sheet structure
in some brain proteins can lead to an Aggregation of the proteins in the brain
increase in amyloid deposit formation,
characteristic of some neurodegenerative This question is describing changes in protein structure.
diseases. What is the primary biochemical Aggregation occurs when proteins clump together
process that follows the increase in beta- inappropriately, causing plaques like amyloid deposits to
pleated sheet structure that leads to the accumulate.
development of the amyloid deposits?
An increase in glycogen formation in the
brain cells
Aggregation of the proteins in the brain
Secretion of glucagon, leading to excessive
ketogenesis
An increase in anaerobic metabolism of
glucose in the brain
WGU C785 Final Exam with Complete Solutions
, WGU C785 Final Exam with Complete Solutions
correct answer
Which level of protein structure is
Primary structure
determined by the sequence of amino
acids? The primary structure of a protein is simply the sequence of
amino acids held together by peptide bonds.
Secondary structure
Quaternary structure
Tertiary structure
Primary structure
correct answer
Which force is most influential in
Hydrogen bonding
determining the secondary structure of a
protein? The secondary structure of a protein is built by hydrogen
bonds between the carboxyl groups and amino groups on the
Hydrophobic effect backbones of the amino acids.
Disulfide bonding
Hydrogen bonding
Electrostatic interactions
correct answer
Which amino acid would most likely
participate in hydrogen bonds? Amino Acid structure 4
This is a polar, uncharged amino acid due to the OH group on
the side chain. Polar, uncharged amino acids containing
oxygen or NH groups make hydrogen bonds.
correct answer
Which portion of the amino acid is inside the
box? Side Chain
The box is surrounding the section below The side chain is the variable group of the amino acid, also
the Alpha Carbon called the R group. Every amino acid has the same amino
group, carboxylic acid group, and an alpha carbon, but the
side chain is different.
correct answer
Which pair of amino acids will most likely
interact through hydrophobic forces Both of these amino acids are non-polar and therefore can
between their side chains? interact together with a hydrophobic interaction. Please note
that the "S" in the amino acid on the right is non-polar, while
the "SH" group in answer choice D is polar. The S must have an
H to be polar and is otherwise non-polar.
WGU C785 Final Exam with Complete Solutions
correct answer
A mutation in the beta-hemoglobin gene,
which results in the replacement of the The original amino acid in a healthy patient is glutamate, which
amino acid glutamate in position 6 with the is negatively charged. The mutated amino acid is valine, which
amino acid valine, leads to the development is non-polar. Valine is causing sickle cell anemia. The best
of sickle cell anemia. The structures of amino acid to replace valine so that the patient is healthy
glutamate and valine are shown below. again would be the one most like glutamate, so any negatively
charged amino acid.
If the beta hemoglobin gene in a patient
with sickle-cell anemia were to be edited so
that the valine in position 6 was replaced
with a different amino acid, which
replacement for valine would be expected
to have the best clinical outcome, in theory,
for the patient? (Assume the valine can
potentially be replaced with any amino acid
other than glutamate.)
correct answer
Secondary, tertiary, and quaternary levels of
protein structure can all be impacted by Placement of the protein in a solution with a low pH
exposing a protein to which treatment?
Changes in pH affect hydrogen bonds and ionic bonds.
Change of a hydrophobic amino acid to a Hydrogen bonds in the backbone of amino acids occur in
different hydrophobic amino acid secondary structure, and both hydrogen bonds and ionic
bonds occur in the side chains of amino acids in tertiary
Addition of a reducing agent structure.
Placement of the protein in a solution with a
low pH
Increase in the concentration of the protein
in solution
correct answer
An increase in beta-pleated sheet structure
in some brain proteins can lead to an Aggregation of the proteins in the brain
increase in amyloid deposit formation,
characteristic of some neurodegenerative This question is describing changes in protein structure.
diseases. What is the primary biochemical Aggregation occurs when proteins clump together
process that follows the increase in beta- inappropriately, causing plaques like amyloid deposits to
pleated sheet structure that leads to the accumulate.
development of the amyloid deposits?
An increase in glycogen formation in the
brain cells
Aggregation of the proteins in the brain
Secretion of glucagon, leading to excessive
ketogenesis
An increase in anaerobic metabolism of
glucose in the brain
WGU C785 Final Exam with Complete Solutions
, WGU C785 Final Exam with Complete Solutions
correct answer
Which level of protein structure is
Primary structure
determined by the sequence of amino
acids? The primary structure of a protein is simply the sequence of
amino acids held together by peptide bonds.
Secondary structure
Quaternary structure
Tertiary structure
Primary structure
correct answer
Which force is most influential in
Hydrogen bonding
determining the secondary structure of a
protein? The secondary structure of a protein is built by hydrogen
bonds between the carboxyl groups and amino groups on the
Hydrophobic effect backbones of the amino acids.
Disulfide bonding
Hydrogen bonding
Electrostatic interactions
correct answer
Which amino acid would most likely
participate in hydrogen bonds? Amino Acid structure 4
This is a polar, uncharged amino acid due to the OH group on
the side chain. Polar, uncharged amino acids containing
oxygen or NH groups make hydrogen bonds.
correct answer
Which portion of the amino acid is inside the
box? Side Chain
The box is surrounding the section below The side chain is the variable group of the amino acid, also
the Alpha Carbon called the R group. Every amino acid has the same amino
group, carboxylic acid group, and an alpha carbon, but the
side chain is different.
correct answer
Which pair of amino acids will most likely
interact through hydrophobic forces Both of these amino acids are non-polar and therefore can
between their side chains? interact together with a hydrophobic interaction. Please note
that the "S" in the amino acid on the right is non-polar, while
the "SH" group in answer choice D is polar. The S must have an
H to be polar and is otherwise non-polar.
WGU C785 Final Exam with Complete Solutions
