MLA SB A Qu estion B an k
Leukaemia
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph
Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026
,BLOOD AND LY MPH Question 1 of 50
Leukaemia Acute lymphoblastic leukaemia
A 3-year-old girl presents with fatigue, pallor, easy bruising, and bone pain over several weeks. Full blood count shows pancytopenia with
circulating blast cells. What is the most likely diagnosis?
A Polycythaemia vera
B Myelodysplastic syndrome
C Chronic myeloid leukaemia
D Acute lymphoblastic leukaemia
E Chronic lymphocytic leukaemia
Select the single best answer.
,BLOOD AND LY MPH Question 1 of 50 — Answer
Leukaemia Acute lymphoblastic leukaemia
A 3-year-old girl presents with fatigue, pallor, easy bruising, and bone pain over several weeks. Full blood count shows pancytopenia with circulating blast cells. What is the
most likely diagnosis?
A Polycythaemia vera
B Myelodysplastic syndrome
C Chronic myeloid leukaemia
D Acute lymphoblastic leukaemia ✓ Correct
E Chronic lymphocytic leukaemia
EXPLANATION
ALL is the most common childhood malignancy, typically presenting with bone marrow failure symptoms (fatigue, pallor, bruising, infection) and bone pain, alongside
pancytopenia and circulating blasts.
, BLOOD AND LY MPH Question 2 of 50
Leukaemia Acute lymphoblastic leukaemia
🖼
The blood film shown is from the same child. Which finding is consistent with lymphoblasts rather INSERT IMAGE
than myeloblasts? Peripheral blood film showing lymphoblasts with scant cytoplasm and
no Auer rods
A Absence of Auer rods within the blast cells
B Presence of ring sideroblasts
C Presence of smudge cells only
D Presence of schistocytes
E Presence of Auer rods within the blast cells
Select the single best answer.
Leukaemia
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph
Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026
,BLOOD AND LY MPH Question 1 of 50
Leukaemia Acute lymphoblastic leukaemia
A 3-year-old girl presents with fatigue, pallor, easy bruising, and bone pain over several weeks. Full blood count shows pancytopenia with
circulating blast cells. What is the most likely diagnosis?
A Polycythaemia vera
B Myelodysplastic syndrome
C Chronic myeloid leukaemia
D Acute lymphoblastic leukaemia
E Chronic lymphocytic leukaemia
Select the single best answer.
,BLOOD AND LY MPH Question 1 of 50 — Answer
Leukaemia Acute lymphoblastic leukaemia
A 3-year-old girl presents with fatigue, pallor, easy bruising, and bone pain over several weeks. Full blood count shows pancytopenia with circulating blast cells. What is the
most likely diagnosis?
A Polycythaemia vera
B Myelodysplastic syndrome
C Chronic myeloid leukaemia
D Acute lymphoblastic leukaemia ✓ Correct
E Chronic lymphocytic leukaemia
EXPLANATION
ALL is the most common childhood malignancy, typically presenting with bone marrow failure symptoms (fatigue, pallor, bruising, infection) and bone pain, alongside
pancytopenia and circulating blasts.
, BLOOD AND LY MPH Question 2 of 50
Leukaemia Acute lymphoblastic leukaemia
🖼
The blood film shown is from the same child. Which finding is consistent with lymphoblasts rather INSERT IMAGE
than myeloblasts? Peripheral blood film showing lymphoblasts with scant cytoplasm and
no Auer rods
A Absence of Auer rods within the blast cells
B Presence of ring sideroblasts
C Presence of smudge cells only
D Presence of schistocytes
E Presence of Auer rods within the blast cells
Select the single best answer.
