Anaemia
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph
Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026
,BLOOD AND LYMPH Question 1 of 50
Anaemia Chronic kidney disease: anaemia
A 58-year-old man with stage 4 chronic kidney disease is found to have a normocytic anaemia. What is the most likely underlying cause?
A Vitamin B12 deficiency
B Bone marrow infiltration
C Haemolysis
D Reduced erythropoietin production by the kidneys
E Acute blood loss
Select the single best answer.
,BLOOD AND LYMPH Question 1 of 50 — Answer
Anaemia Chronic kidney disease: anaemia
A 58-year-old man with stage 4 chronic kidney disease is found to have a normocytic anaemia. What is the most likely underlying cause?
A Vitamin B12 deficiency
B Bone marrow infiltration
C Haemolysis
D Reduced erythropoietin production by the kidneys ✓ Correct
E Acute blood loss
EXPLANATION
Anaemia in CKD is primarily due to reduced renal erythropoietin production, leading to decreased red cell production; it is typically normocytic and normochromic.
, BLOOD AND LYMPH Question 2 of 50
Anaemia Pregnancy: anaemia
A pregnant woman at 28 weeks gestation has a haemoglobin of 105 g/L on routine screening, with a low MCV. What is the most likely
underlying cause?
A Aplastic anaemia
B Myelofibrosis
C Iron deficiency anaemia, exacerbated by increased iron demands and plasma volume expansion in pregnancy
D Sickle cell disease
E Polycythaemia vera
Select the single best answer.