CHEM 219: Principles of Organic
Chemistry
Comprehensive Final Exam Review (Modules 1-8)
700 Verified Practice Questions | Portage Learning 2026/2027 Edition
MOD 1: FUNDAMENTALS
Q1: Which of the following is an example of a chemical property?
A. Boiling point | B. Density | C. Flammability | D. Malleability
Correct Answer: C
Final Review Tip: Flammability describes how a substance reacts chemically with oxygen to form new substances.
MOD 2: BONDING
Q2: What is the hybridization of a carbon atom involved in a triple bond?
A. sp | B. sp2 | C. sp3 | D. sp3d
Correct Answer: A
Final Review Tip: A carbon in a triple bond has two electron domains, resulting in sp hybridization and a linear geometry
(180°).
MOD 3: FUNCTIONAL GROUPS
Q3: Which functional group contains a nitrogen atom bonded to a carbonyl group?
A. Amine | B. Amide | C. Nitrile | D. Nitro
Correct Answer: B
Final Review Tip: An amide has the structure R-C(=O)-NH2 (or NHR, NR2).
MOD 4: HYDROCARBONS
Q4: According to Markovnikov's rule, in the addition of HBr to 1-butene, where does the
Bromine atom attach?
A. C1 | B. C2 | C. C3 | D. C4
Correct Answer: B
Final Review Tip: The hydrogen adds to the carbon with more hydrogens (C1), and the bromine adds to the more
substituted carbon (C2).
MOD 5: ALCOHOLS/ETHERS
Q5: Which of these will NOT undergo oxidation with K2Cr2O7?
A. Ethanol | B. 2-propanol | C. 2-methyl-2-propanol | D. Methanol
Correct Answer: C
Final Review Tip: Tertiary alcohols cannot be oxidized because the carbon bearing the -OH group has no C-H bonds to
break.
CHEM 219 Final - Page 1
,MOD 6: CARBONYLS
Q6: What is the product of the reduction of a ketone?
A. Primary alcohol | B. Secondary alcohol | C. Carboxylic acid | D. Aldehyde
Correct Answer: B
Final Review Tip: Reduction of a ketone (like acetone) yields a secondary alcohol (like 2-propanol).
MOD 7: CARBOXYLIC ACIDS/ESTERS
Q7: The hydrolysis of an ester in the presence of a strong base is called:
A. Esterification | B. Saponification | C. Condensation | D. Hydrogenation
Correct Answer: B
Final Review Tip: Saponification is base-catalyzed ester hydrolysis, commonly used to produce soap from fats.
MOD 8: BIOCHEMISTRY
Q8: A link between two amino acids in a protein is called a:
A. Glycosidic bond | B. Peptide bond | C. Ester bond | D. Phosphodiester bond
Correct Answer: B
Final Review Tip: Peptide bonds are amide linkages that connect amino acids to form polypeptide chains.
MOD 1: FUNDAMENTALS
Q9: Which of the following is an example of a chemical property?
A. Boiling point | B. Density | C. Flammability | D. Malleability
Correct Answer: C
Final Review Tip: Flammability describes how a substance reacts chemically with oxygen to form new substances.
MOD 2: BONDING
Q10: What is the hybridization of a carbon atom involved in a triple bond?
A. sp | B. sp2 | C. sp3 | D. sp3d
Correct Answer: A
Final Review Tip: A carbon in a triple bond has two electron domains, resulting in sp hybridization and a linear geometry
(180°).
MOD 3: FUNCTIONAL GROUPS
Q11: Which functional group contains a nitrogen atom bonded to a carbonyl group?
A. Amine | B. Amide | C. Nitrile | D. Nitro
Correct Answer: B
Final Review Tip: An amide has the structure R-C(=O)-NH2 (or NHR, NR2).
MOD 4: HYDROCARBONS
Q12: According to Markovnikov's rule, in the addition of HBr to 1-butene, where does
the Bromine atom attach?
A. C1 | B. C2 | C. C3 | D. C4
Correct Answer: B
Final Review Tip: The hydrogen adds to the carbon with more hydrogens (C1), and the bromine adds to the more
substituted carbon (C2).
CHEM 219 Final - Page 2
,MOD 5: ALCOHOLS/ETHERS
Q13: Which of these will NOT undergo oxidation with K2Cr2O7?
A. Ethanol | B. 2-propanol | C. 2-methyl-2-propanol | D. Methanol
Correct Answer: C
Final Review Tip: Tertiary alcohols cannot be oxidized because the carbon bearing the -OH group has no C-H bonds to
break.
MOD 6: CARBONYLS
Q14: What is the product of the reduction of a ketone?
A. Primary alcohol | B. Secondary alcohol | C. Carboxylic acid | D. Aldehyde
Correct Answer: B
Final Review Tip: Reduction of a ketone (like acetone) yields a secondary alcohol (like 2-propanol).
MOD 7: CARBOXYLIC ACIDS/ESTERS
Q15: The hydrolysis of an ester in the presence of a strong base is called:
A. Esterification | B. Saponification | C. Condensation | D. Hydrogenation
Correct Answer: B
Final Review Tip: Saponification is base-catalyzed ester hydrolysis, commonly used to produce soap from fats.
MOD 8: BIOCHEMISTRY
Q16: A link between two amino acids in a protein is called a:
A. Glycosidic bond | B. Peptide bond | C. Ester bond | D. Phosphodiester bond
Correct Answer: B
Final Review Tip: Peptide bonds are amide linkages that connect amino acids to form polypeptide chains.
MOD 1: FUNDAMENTALS
Q17: Which of the following is an example of a chemical property?
A. Boiling point | B. Density | C. Flammability | D. Malleability
Correct Answer: C
Final Review Tip: Flammability describes how a substance reacts chemically with oxygen to form new substances.
MOD 2: BONDING
Q18: What is the hybridization of a carbon atom involved in a triple bond?
A. sp | B. sp2 | C. sp3 | D. sp3d
Correct Answer: A
Final Review Tip: A carbon in a triple bond has two electron domains, resulting in sp hybridization and a linear geometry
(180°).
MOD 3: FUNCTIONAL GROUPS
Q19: Which functional group contains a nitrogen atom bonded to a carbonyl group?
A. Amine | B. Amide | C. Nitrile | D. Nitro
Correct Answer: B
Final Review Tip: An amide has the structure R-C(=O)-NH2 (or NHR, NR2).
CHEM 219 Final - Page 3
, MOD 4: HYDROCARBONS
Q20: According to Markovnikov's rule, in the addition of HBr to 1-butene, where does
the Bromine atom attach?
A. C1 | B. C2 | C. C3 | D. C4
Correct Answer: B
Final Review Tip: The hydrogen adds to the carbon with more hydrogens (C1), and the bromine adds to the more
substituted carbon (C2).
MOD 5: ALCOHOLS/ETHERS
Q21: Which of these will NOT undergo oxidation with K2Cr2O7?
A. Ethanol | B. 2-propanol | C. 2-methyl-2-propanol | D. Methanol
Correct Answer: C
Final Review Tip: Tertiary alcohols cannot be oxidized because the carbon bearing the -OH group has no C-H bonds to
break.
MOD 6: CARBONYLS
Q22: What is the product of the reduction of a ketone?
A. Primary alcohol | B. Secondary alcohol | C. Carboxylic acid | D. Aldehyde
Correct Answer: B
Final Review Tip: Reduction of a ketone (like acetone) yields a secondary alcohol (like 2-propanol).
MOD 7: CARBOXYLIC ACIDS/ESTERS
Q23: The hydrolysis of an ester in the presence of a strong base is called:
A. Esterification | B. Saponification | C. Condensation | D. Hydrogenation
Correct Answer: B
Final Review Tip: Saponification is base-catalyzed ester hydrolysis, commonly used to produce soap from fats.
MOD 8: BIOCHEMISTRY
Q24: A link between two amino acids in a protein is called a:
A. Glycosidic bond | B. Peptide bond | C. Ester bond | D. Phosphodiester bond
Correct Answer: B
Final Review Tip: Peptide bonds are amide linkages that connect amino acids to form polypeptide chains.
MOD 1: FUNDAMENTALS
Q25: Which of the following is an example of a chemical property?
A. Boiling point | B. Density | C. Flammability | D. Malleability
Correct Answer: C
Final Review Tip: Flammability describes how a substance reacts chemically with oxygen to form new substances.
MOD 2: BONDING
Q26: What is the hybridization of a carbon atom involved in a triple bond?
A. sp | B. sp2 | C. sp3 | D. sp3d
Correct Answer: A
Final Review Tip: A carbon in a triple bond has two electron domains, resulting in sp hybridization and a linear geometry
(180°).
CHEM 219 Final - Page 4
Chemistry
Comprehensive Final Exam Review (Modules 1-8)
700 Verified Practice Questions | Portage Learning 2026/2027 Edition
MOD 1: FUNDAMENTALS
Q1: Which of the following is an example of a chemical property?
A. Boiling point | B. Density | C. Flammability | D. Malleability
Correct Answer: C
Final Review Tip: Flammability describes how a substance reacts chemically with oxygen to form new substances.
MOD 2: BONDING
Q2: What is the hybridization of a carbon atom involved in a triple bond?
A. sp | B. sp2 | C. sp3 | D. sp3d
Correct Answer: A
Final Review Tip: A carbon in a triple bond has two electron domains, resulting in sp hybridization and a linear geometry
(180°).
MOD 3: FUNCTIONAL GROUPS
Q3: Which functional group contains a nitrogen atom bonded to a carbonyl group?
A. Amine | B. Amide | C. Nitrile | D. Nitro
Correct Answer: B
Final Review Tip: An amide has the structure R-C(=O)-NH2 (or NHR, NR2).
MOD 4: HYDROCARBONS
Q4: According to Markovnikov's rule, in the addition of HBr to 1-butene, where does the
Bromine atom attach?
A. C1 | B. C2 | C. C3 | D. C4
Correct Answer: B
Final Review Tip: The hydrogen adds to the carbon with more hydrogens (C1), and the bromine adds to the more
substituted carbon (C2).
MOD 5: ALCOHOLS/ETHERS
Q5: Which of these will NOT undergo oxidation with K2Cr2O7?
A. Ethanol | B. 2-propanol | C. 2-methyl-2-propanol | D. Methanol
Correct Answer: C
Final Review Tip: Tertiary alcohols cannot be oxidized because the carbon bearing the -OH group has no C-H bonds to
break.
CHEM 219 Final - Page 1
,MOD 6: CARBONYLS
Q6: What is the product of the reduction of a ketone?
A. Primary alcohol | B. Secondary alcohol | C. Carboxylic acid | D. Aldehyde
Correct Answer: B
Final Review Tip: Reduction of a ketone (like acetone) yields a secondary alcohol (like 2-propanol).
MOD 7: CARBOXYLIC ACIDS/ESTERS
Q7: The hydrolysis of an ester in the presence of a strong base is called:
A. Esterification | B. Saponification | C. Condensation | D. Hydrogenation
Correct Answer: B
Final Review Tip: Saponification is base-catalyzed ester hydrolysis, commonly used to produce soap from fats.
MOD 8: BIOCHEMISTRY
Q8: A link between two amino acids in a protein is called a:
A. Glycosidic bond | B. Peptide bond | C. Ester bond | D. Phosphodiester bond
Correct Answer: B
Final Review Tip: Peptide bonds are amide linkages that connect amino acids to form polypeptide chains.
MOD 1: FUNDAMENTALS
Q9: Which of the following is an example of a chemical property?
A. Boiling point | B. Density | C. Flammability | D. Malleability
Correct Answer: C
Final Review Tip: Flammability describes how a substance reacts chemically with oxygen to form new substances.
MOD 2: BONDING
Q10: What is the hybridization of a carbon atom involved in a triple bond?
A. sp | B. sp2 | C. sp3 | D. sp3d
Correct Answer: A
Final Review Tip: A carbon in a triple bond has two electron domains, resulting in sp hybridization and a linear geometry
(180°).
MOD 3: FUNCTIONAL GROUPS
Q11: Which functional group contains a nitrogen atom bonded to a carbonyl group?
A. Amine | B. Amide | C. Nitrile | D. Nitro
Correct Answer: B
Final Review Tip: An amide has the structure R-C(=O)-NH2 (or NHR, NR2).
MOD 4: HYDROCARBONS
Q12: According to Markovnikov's rule, in the addition of HBr to 1-butene, where does
the Bromine atom attach?
A. C1 | B. C2 | C. C3 | D. C4
Correct Answer: B
Final Review Tip: The hydrogen adds to the carbon with more hydrogens (C1), and the bromine adds to the more
substituted carbon (C2).
CHEM 219 Final - Page 2
,MOD 5: ALCOHOLS/ETHERS
Q13: Which of these will NOT undergo oxidation with K2Cr2O7?
A. Ethanol | B. 2-propanol | C. 2-methyl-2-propanol | D. Methanol
Correct Answer: C
Final Review Tip: Tertiary alcohols cannot be oxidized because the carbon bearing the -OH group has no C-H bonds to
break.
MOD 6: CARBONYLS
Q14: What is the product of the reduction of a ketone?
A. Primary alcohol | B. Secondary alcohol | C. Carboxylic acid | D. Aldehyde
Correct Answer: B
Final Review Tip: Reduction of a ketone (like acetone) yields a secondary alcohol (like 2-propanol).
MOD 7: CARBOXYLIC ACIDS/ESTERS
Q15: The hydrolysis of an ester in the presence of a strong base is called:
A. Esterification | B. Saponification | C. Condensation | D. Hydrogenation
Correct Answer: B
Final Review Tip: Saponification is base-catalyzed ester hydrolysis, commonly used to produce soap from fats.
MOD 8: BIOCHEMISTRY
Q16: A link between two amino acids in a protein is called a:
A. Glycosidic bond | B. Peptide bond | C. Ester bond | D. Phosphodiester bond
Correct Answer: B
Final Review Tip: Peptide bonds are amide linkages that connect amino acids to form polypeptide chains.
MOD 1: FUNDAMENTALS
Q17: Which of the following is an example of a chemical property?
A. Boiling point | B. Density | C. Flammability | D. Malleability
Correct Answer: C
Final Review Tip: Flammability describes how a substance reacts chemically with oxygen to form new substances.
MOD 2: BONDING
Q18: What is the hybridization of a carbon atom involved in a triple bond?
A. sp | B. sp2 | C. sp3 | D. sp3d
Correct Answer: A
Final Review Tip: A carbon in a triple bond has two electron domains, resulting in sp hybridization and a linear geometry
(180°).
MOD 3: FUNCTIONAL GROUPS
Q19: Which functional group contains a nitrogen atom bonded to a carbonyl group?
A. Amine | B. Amide | C. Nitrile | D. Nitro
Correct Answer: B
Final Review Tip: An amide has the structure R-C(=O)-NH2 (or NHR, NR2).
CHEM 219 Final - Page 3
, MOD 4: HYDROCARBONS
Q20: According to Markovnikov's rule, in the addition of HBr to 1-butene, where does
the Bromine atom attach?
A. C1 | B. C2 | C. C3 | D. C4
Correct Answer: B
Final Review Tip: The hydrogen adds to the carbon with more hydrogens (C1), and the bromine adds to the more
substituted carbon (C2).
MOD 5: ALCOHOLS/ETHERS
Q21: Which of these will NOT undergo oxidation with K2Cr2O7?
A. Ethanol | B. 2-propanol | C. 2-methyl-2-propanol | D. Methanol
Correct Answer: C
Final Review Tip: Tertiary alcohols cannot be oxidized because the carbon bearing the -OH group has no C-H bonds to
break.
MOD 6: CARBONYLS
Q22: What is the product of the reduction of a ketone?
A. Primary alcohol | B. Secondary alcohol | C. Carboxylic acid | D. Aldehyde
Correct Answer: B
Final Review Tip: Reduction of a ketone (like acetone) yields a secondary alcohol (like 2-propanol).
MOD 7: CARBOXYLIC ACIDS/ESTERS
Q23: The hydrolysis of an ester in the presence of a strong base is called:
A. Esterification | B. Saponification | C. Condensation | D. Hydrogenation
Correct Answer: B
Final Review Tip: Saponification is base-catalyzed ester hydrolysis, commonly used to produce soap from fats.
MOD 8: BIOCHEMISTRY
Q24: A link between two amino acids in a protein is called a:
A. Glycosidic bond | B. Peptide bond | C. Ester bond | D. Phosphodiester bond
Correct Answer: B
Final Review Tip: Peptide bonds are amide linkages that connect amino acids to form polypeptide chains.
MOD 1: FUNDAMENTALS
Q25: Which of the following is an example of a chemical property?
A. Boiling point | B. Density | C. Flammability | D. Malleability
Correct Answer: C
Final Review Tip: Flammability describes how a substance reacts chemically with oxygen to form new substances.
MOD 2: BONDING
Q26: What is the hybridization of a carbon atom involved in a triple bond?
A. sp | B. sp2 | C. sp3 | D. sp3d
Correct Answer: A
Final Review Tip: A carbon in a triple bond has two electron domains, resulting in sp hybridization and a linear geometry
(180°).
CHEM 219 Final - Page 4
