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NURSE WISEMAN 2026/2027 MEDICINE
,NURS 615 Opioids, NSAIDs, and Gout
Nurse Practitioners Review Exam
(Latest 2026/ 2027 Update) 100%
Verified Questions & Answers |
Grade A+
Week 8 Q1: Differentiate between low-dose and high-
dose colchicine. - ANSWER✅✅Low-dose colchicine
for an acute gout flare is 1.2 mg at the first sign of flare,
followed by 0.6 mg one hour later. High-dose colchicine
refers to older/more aggressive repeated dosing
regimens; it is not preferred because it increases toxicity,
especially gastrointestinal adverse effects such as nausea,
vomiting, diarrhea, and risk in renal/hepatic impairment.
The PowerPoint emphasizes low-dose vs higher doses and
provides the low-dose regimen.
Week 8 Q2: What lab values should be monitored with
gout and why? - ANSWER✅✅Monitor serum uric
acid to assess hyperuricemia and response to urate-
lowering therapy; renal function/BUN/creatinine/eGFR
because gout drugs are renally excreted and CKD affects
drug choice/dosing; liver function tests because
allopurinol/febuxostat/probenecid/colchicine are
metabolized by the liver and febuxostat/allopurinol can
cause hepatotoxicity; CBC when clinically indicated
, because some gout therapies can rarely affect blood
counts. The goal is to lower uric acid while avoiding
renal/hepatic toxicity and drug accumulation.
Week 8 Q3: What patient education should you provide
when prescribing colchicine? - ANSWER✅✅Take
colchicine exactly as prescribed: 1.2 mg at the first sign of
a gout flare, then 0.6 mg one hour later if using the low-
dose regimen. It decreases inflammation around urate
crystals but is not an analgesic or antipyretic. Report
severe diarrhea, vomiting, abdominal pain, muscle
weakness, numbness/tingling, unusual bruising/bleeding,
or signs of infection. Avoid taking extra doses. Tell the
provider about kidney disease, liver disease, peptic ulcer
disease, and interacting medications.
Week 8 Q4: What are adverse effects of corticosteroids if
administered for six months or more? -
ANSWER✅✅Long-term corticosteroids can suppress
immune response and mask infection, increase
susceptibility to TB/herpes/varicella, worsen GI irritation
or ulcers, cause acne and delayed wound healing, cause
osteoporosis and fracture risk from calcium loss, cause
sodium/fluid retention, increase blood glucose, and
contribute to anxiety/insomnia. Patients should know to
watch for infection even if fever/redness is muted,
protect bones with prescriber-recommended
• Nursing Exam Prep Made Easy — Get
Your Documents Today!
NURSE WISEMAN 2026/2027 MEDICINE
,NURS 615 Opioids, NSAIDs, and Gout
Nurse Practitioners Review Exam
(Latest 2026/ 2027 Update) 100%
Verified Questions & Answers |
Grade A+
Week 8 Q1: Differentiate between low-dose and high-
dose colchicine. - ANSWER✅✅Low-dose colchicine
for an acute gout flare is 1.2 mg at the first sign of flare,
followed by 0.6 mg one hour later. High-dose colchicine
refers to older/more aggressive repeated dosing
regimens; it is not preferred because it increases toxicity,
especially gastrointestinal adverse effects such as nausea,
vomiting, diarrhea, and risk in renal/hepatic impairment.
The PowerPoint emphasizes low-dose vs higher doses and
provides the low-dose regimen.
Week 8 Q2: What lab values should be monitored with
gout and why? - ANSWER✅✅Monitor serum uric
acid to assess hyperuricemia and response to urate-
lowering therapy; renal function/BUN/creatinine/eGFR
because gout drugs are renally excreted and CKD affects
drug choice/dosing; liver function tests because
allopurinol/febuxostat/probenecid/colchicine are
metabolized by the liver and febuxostat/allopurinol can
cause hepatotoxicity; CBC when clinically indicated
, because some gout therapies can rarely affect blood
counts. The goal is to lower uric acid while avoiding
renal/hepatic toxicity and drug accumulation.
Week 8 Q3: What patient education should you provide
when prescribing colchicine? - ANSWER✅✅Take
colchicine exactly as prescribed: 1.2 mg at the first sign of
a gout flare, then 0.6 mg one hour later if using the low-
dose regimen. It decreases inflammation around urate
crystals but is not an analgesic or antipyretic. Report
severe diarrhea, vomiting, abdominal pain, muscle
weakness, numbness/tingling, unusual bruising/bleeding,
or signs of infection. Avoid taking extra doses. Tell the
provider about kidney disease, liver disease, peptic ulcer
disease, and interacting medications.
Week 8 Q4: What are adverse effects of corticosteroids if
administered for six months or more? -
ANSWER✅✅Long-term corticosteroids can suppress
immune response and mask infection, increase
susceptibility to TB/herpes/varicella, worsen GI irritation
or ulcers, cause acne and delayed wound healing, cause
osteoporosis and fracture risk from calcium loss, cause
sodium/fluid retention, increase blood glucose, and
contribute to anxiety/insomnia. Patients should know to
watch for infection even if fever/redness is muted,
protect bones with prescriber-recommended
