APhA Immunization Exam Test Questions and Answers Rated A
The National Vaccine Advisory Committee 2013 Standards
for Adult Immunization Practice and the 2016 Interna-
Integral to increasing vaccination rates
tional Pharmaceutical Federation global report identify
pharmacists as:
Under the direction of the U.S. Department of Health and
Increase the proportion of persons who are vaccinated
Human Services, the Healthy People initiative has identi-
annually against seasonal influenza
fied the following as a goal for 2030:
Membership in state Immunization coalition to serve as an
Opportunities for Advocacy and Collaboration include:
expert on policy and practice issues attecting pharmacy
Which of the following diseases have been eradicated
Smallpox - eradicated in 1980 by WHO
worldwide, allowing vaccination to be discontinued?
Which of the following is one of the five guidelines iden-
tified by the APhA Board of Trustees in 2019 to assist Prevention, Partnership, Quality, Documentation and Em-
pharmacists in incorporating immunization activities into powerment
their practice?
Active Immunity Long-term protection but takes 2 weeks to work
Innate Immunity Barrier defense mechanism
Adaptive Immunity Also known as acquired
Passive Immunity Antibodies from an external source
Evoke the immune response and bind to specific antibod-
Antigens
ies
T/F: Vaccines contain antibodies which are recognized by
False
the immune system.
1. Post-exposure prophylaxis is needed right away
2. Give both Hep B immune globulin (HBIG) and Hepatitis
What can a pharmacist do to reduce the risk of getting
B vaccine
hepatitis B after exposure?
3. HBIG contains antibodies that provide immediate pro-
tection via passive immunity
, APhA Immunization Exam Test Questions and Answers Rated A
4. When a person is fully vaccinated, the hepatitis B vaccine
provides long-term protection.
1. Attenuated
2. Stimulates both humoral and cell-mediated immune
response
Live Vaccines are:
3. May be interfered with by circulating antibodies
4. Not given to children less than 12 months of age due to
presence of maternal antibodies
1. Killed virus or bacteria
2. Does not replicate
3. Stimulates humoral immunity (antibodies)
4. May be given to people who have received blood prod-
Inactivated Vaccines are:
ucts or live vaccines, regardless of timing.
5. Predominantly given to infants (less than 12 months)
because they may have circulating maternal antibodies
which could reduce the ettectiveness of a live vaccines.
T/F: Inactivated vaccines do NOT have minimum intervals
True
between administered vaccines
T/F: Inactivated vaccines are not attected by live vaccines
True
and visa versa.
If two live vaccines are given simultaneously sly on the 28-day minimum interval so that each vaccine can repli-
same day, then you must wait minimum interval. cate properly.
Live vaccines followed by blood products (contain anti-
2 weeks.
bodies) require minimum interval.
Which of the following is an example of passive immuni-
ty?
d.) Maternal antibodies
a.) Contracting measles
b.) Hep B Vaccine
, c.) Skin Barrier
d.) Maternal antibodies
Circulating antibodies may interfere with immune re-
Why is spacing and timing of vaccines important?
sponse
How long does it take for the immune system to provide
protection by producing disease-specific antibodies and 14 days
memory cells?
When a patient is exposed to an antigen that triggers the
When does Active Immunity occur? body's immune system to produce it's own disease-spe-
cific antibodies and memory cells.
Children less than what age do not mount an adequate
2 years.
immune response to t-cell independent immunity?
Which of the following is found in vaccines to evoke an
Antigens
immune response?
What does attenuated mean? weakened
LAIV4 is the abbreviation for: Live Attenuated Influenza Vaccine
RV1, RV5 is the abbreviation for: Rotavirus
VAR is the abbreviation for: Varicella
MMR is the abbreviation for: Measles, mumps, rubella
MMRV is the abbreviation for: Measles, mumps, rubella, varicella
Can inactivated vaccines replicate? No. It does not cause disease.
What are two broad categories that vaccines are classified 1. Live attenuated vaccines
as? 2. Inactivated vaccines
1. Inactivated Vaccines
2. Whole viruses or bacteria
Cellular Vaccines
3. Known as Subunits (fractions)
4. DTP/DTaP
Toxoid Vaccines
, 1. Inactivated Vaccine
2. Subunit (fractions)
3. Inactive or biological toxin
4. Tetanus toxoid
1. Produced by genetic engineering
2. May contain no actual virus or a modified strain of a
Recombinant Vaccine
virus
3. HepB, HPV, RZV, RIV4
1. Patients who currently are immunocompromised
What clinical factors need to be considered before admin-
2. Live attenuated vaccines administered in the previous
istering a lie attenuated vaccine?
28 days.
T/F: MMR is a live attenuated vaccine. True
Which of the following vaccines listed is a live attenuated
vaccine?
a.) Hep B
d.) VAR
b.) Hep A
c.) RZV
d.) VAR
Pneumococcal polysaccharide vaccine (PPSV23) is best
Inactivated Polysaccharide Vaccine
categorized as what type of vaccine?
Which of the following is true regarding the use of mRNA
in vaccine technology?
a.) mRNA is extremely stable in a host's body.
b.) mRNA is the genetic blueprint that tells your body how
b.) mRNA is the genetic blueprint that tells your body how
to make a particular protein subunit of a virus which, after
to make a particular protein subunit of a virus which, after
being produced, will elicit an immune response.
being produced, will elicit an immune response.
c.) mRNA vaccine technology requires replication similar
to a live attenuated vaccine.
d.) mRNA vaccine technology elicits its immune response
and protects the host by altering the host's DNA.
The National Vaccine Advisory Committee 2013 Standards
for Adult Immunization Practice and the 2016 Interna-
Integral to increasing vaccination rates
tional Pharmaceutical Federation global report identify
pharmacists as:
Under the direction of the U.S. Department of Health and
Increase the proportion of persons who are vaccinated
Human Services, the Healthy People initiative has identi-
annually against seasonal influenza
fied the following as a goal for 2030:
Membership in state Immunization coalition to serve as an
Opportunities for Advocacy and Collaboration include:
expert on policy and practice issues attecting pharmacy
Which of the following diseases have been eradicated
Smallpox - eradicated in 1980 by WHO
worldwide, allowing vaccination to be discontinued?
Which of the following is one of the five guidelines iden-
tified by the APhA Board of Trustees in 2019 to assist Prevention, Partnership, Quality, Documentation and Em-
pharmacists in incorporating immunization activities into powerment
their practice?
Active Immunity Long-term protection but takes 2 weeks to work
Innate Immunity Barrier defense mechanism
Adaptive Immunity Also known as acquired
Passive Immunity Antibodies from an external source
Evoke the immune response and bind to specific antibod-
Antigens
ies
T/F: Vaccines contain antibodies which are recognized by
False
the immune system.
1. Post-exposure prophylaxis is needed right away
2. Give both Hep B immune globulin (HBIG) and Hepatitis
What can a pharmacist do to reduce the risk of getting
B vaccine
hepatitis B after exposure?
3. HBIG contains antibodies that provide immediate pro-
tection via passive immunity
, APhA Immunization Exam Test Questions and Answers Rated A
4. When a person is fully vaccinated, the hepatitis B vaccine
provides long-term protection.
1. Attenuated
2. Stimulates both humoral and cell-mediated immune
response
Live Vaccines are:
3. May be interfered with by circulating antibodies
4. Not given to children less than 12 months of age due to
presence of maternal antibodies
1. Killed virus or bacteria
2. Does not replicate
3. Stimulates humoral immunity (antibodies)
4. May be given to people who have received blood prod-
Inactivated Vaccines are:
ucts or live vaccines, regardless of timing.
5. Predominantly given to infants (less than 12 months)
because they may have circulating maternal antibodies
which could reduce the ettectiveness of a live vaccines.
T/F: Inactivated vaccines do NOT have minimum intervals
True
between administered vaccines
T/F: Inactivated vaccines are not attected by live vaccines
True
and visa versa.
If two live vaccines are given simultaneously sly on the 28-day minimum interval so that each vaccine can repli-
same day, then you must wait minimum interval. cate properly.
Live vaccines followed by blood products (contain anti-
2 weeks.
bodies) require minimum interval.
Which of the following is an example of passive immuni-
ty?
d.) Maternal antibodies
a.) Contracting measles
b.) Hep B Vaccine
, c.) Skin Barrier
d.) Maternal antibodies
Circulating antibodies may interfere with immune re-
Why is spacing and timing of vaccines important?
sponse
How long does it take for the immune system to provide
protection by producing disease-specific antibodies and 14 days
memory cells?
When a patient is exposed to an antigen that triggers the
When does Active Immunity occur? body's immune system to produce it's own disease-spe-
cific antibodies and memory cells.
Children less than what age do not mount an adequate
2 years.
immune response to t-cell independent immunity?
Which of the following is found in vaccines to evoke an
Antigens
immune response?
What does attenuated mean? weakened
LAIV4 is the abbreviation for: Live Attenuated Influenza Vaccine
RV1, RV5 is the abbreviation for: Rotavirus
VAR is the abbreviation for: Varicella
MMR is the abbreviation for: Measles, mumps, rubella
MMRV is the abbreviation for: Measles, mumps, rubella, varicella
Can inactivated vaccines replicate? No. It does not cause disease.
What are two broad categories that vaccines are classified 1. Live attenuated vaccines
as? 2. Inactivated vaccines
1. Inactivated Vaccines
2. Whole viruses or bacteria
Cellular Vaccines
3. Known as Subunits (fractions)
4. DTP/DTaP
Toxoid Vaccines
, 1. Inactivated Vaccine
2. Subunit (fractions)
3. Inactive or biological toxin
4. Tetanus toxoid
1. Produced by genetic engineering
2. May contain no actual virus or a modified strain of a
Recombinant Vaccine
virus
3. HepB, HPV, RZV, RIV4
1. Patients who currently are immunocompromised
What clinical factors need to be considered before admin-
2. Live attenuated vaccines administered in the previous
istering a lie attenuated vaccine?
28 days.
T/F: MMR is a live attenuated vaccine. True
Which of the following vaccines listed is a live attenuated
vaccine?
a.) Hep B
d.) VAR
b.) Hep A
c.) RZV
d.) VAR
Pneumococcal polysaccharide vaccine (PPSV23) is best
Inactivated Polysaccharide Vaccine
categorized as what type of vaccine?
Which of the following is true regarding the use of mRNA
in vaccine technology?
a.) mRNA is extremely stable in a host's body.
b.) mRNA is the genetic blueprint that tells your body how
b.) mRNA is the genetic blueprint that tells your body how
to make a particular protein subunit of a virus which, after
to make a particular protein subunit of a virus which, after
being produced, will elicit an immune response.
being produced, will elicit an immune response.
c.) mRNA vaccine technology requires replication similar
to a live attenuated vaccine.
d.) mRNA vaccine technology elicits its immune response
and protects the host by altering the host's DNA.
