TEST BANK FOR BASIC AND CLINICAL
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PHARMACOLOGY16TH EDITION KATZUNG’S TESTBANK
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/ALL CHS 1-
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66/COMPLETE GUIDE 2024-2025 tr tr
,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a hospital client who
tr tr tr tr tr tr tr tr tr tr tr
is having a computed tomography (CT) scan. The nursing attendant
tr tr tr tr tr tr tr tr tr tr
working on the oncology unit administers chemotherapy to hospital
tr tr tr tr tr tr tr tr tr
clients who have cancer. At the Public Health Department, a nursing
tr tr tr tr tr tr tr tr tr tr tr
attendant administers a measles-mumps-r ubella (MMR) vaccine to a 14-
tr tr tr tr tr tr tr tr tr tr
month-old child as a routine immunization. Which branch of
tr tr tr tr tr tr tr tr
pharmacology best describes the actions of all three
tr tr tr tr tr tr tr tr
nursing attendants? tr
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- tr B
Reasoning :->>>>>> tr
Pharmacology is the study of the biologic effects of chemicals. Nursing tr tr tr tr tr tr tr tr tr tr
attendants are involved with clinical pharmacology or
tr tr tr tr tr tr tr
pharmacotherapeutics, which is a branch of pharmacology that deals with
tr tr tr tr tr tr tr tr tr tr
the uses of drugs to treat,prevent, and diagnose disease. The radiology
tr tr tr tr tr tr tr tr tr tr tr tr
nursing attendant is administering a drug to help diagnose a disease. The
tr tr tr tr tr tr tr tr tr tr tr tr
oncology nursing attendant is administering a drug to help treat a disease.
tr tr tr tr tr tr tr tr tr tr tr tr
Pharmacoeconomics includes any costs involved in drug therapy.
tr tr tr tr tr tr tr tr
Pharmacodynamics involves how a drug affects the body and tr tr tr tr tr tr tr tr
pharmacokinetics is how the body acts on the body. tr tr tr tr tr tr tr tr
2. When involved in phase III drug evaluation studies,
tr tr tr tr tr tr tr
whatr esponsibilities would the nursing attendant have?
tr tr tr tr tr tr tr
A) Working with animals who are given experimental drugs
tr tr tr tr tr tr tr
B) Choosing appropriate hospital clients to be involved in the drug study
tr tr tr tr tr tr tr tr tr t r
C) Monitoring and observing hospital clients closely for adverse effects
tr tr tr tr tr tr tr tr
D) Conducting research to determine effectiveness of the drug tr tr tr tr tr tr tr
,ACCURATE CHOICE:- tr C
Reasoning:->>>>>>
Phase III studies involve use of a drug in a vast clinical population in
tr tr tr tr tr tr tr tr tr tr tr tr tr
whichhospital clients are asked to record any symptoms they experience
tr tr tr tr tr tr tr tr tr tr tr
while taking the drugs. Nursing attendants may be responsible for helping
tr tr tr tr tr tr tr tr tr tr tr
collect and analyzet he information to be shared with the Food and Drug
tr tr tr tr tr tr tr tr tr tr tr tr tr
Administration (FDA)but would not conduct research independently
tr tr tr tr tr tr tr tr
because nursing attendants donot prescribe medications. Use of animals
tr tr tr tr tr tr tr tr tr tr
in drug testing is done in the preclinical trials. Select hospital clients who
tr tr tr tr tr tr tr tr tr tr tr tr tr
are involved in phase II studies to participate in studies where the
tr tr tr tr tr tr tr tr tr tr tr tr
participants have the disease the drug is intended to treat. These hospital
tr tr tr tr tr tr tr tr tr tr tr tr
clients are monitored closely for drug action and adverse effects. Phase I
tr tr tr tr tr tr tr tr tr tr tr tr
studies involve healthy human volunteers who are usually paid for their
tr tr tr tr tr tr tr tr tr tr tr
participation. Nursing attendants may observe for
tr tr tr tr tr tr
adverse effects and toxicity. tr tr tr
3. A physician has ordered intramuscular (IM) injections of morphine, a
tr tr tr tr tr tr tr tr tr
narcotic, every 4 hours as needed for pain in a motor vehicle accident
tr tr tr tr tr tr tr tr tr tr tr tr tr
victim. The nursing attendant is aware this drug has a high abuse potential.
tr tr tr tr tr tr tr tr tr tr tr tr tr
Under what category would morphine be classified?
tr tr tr tr tr tr tr
A) Schedule I tr
B) Schedule II tr
C) Schedule III tr
D) Schedule IV tr
ACCURATE CHOICE:- tr B
Reasoning:->>>>>>
Narcotics with a high abuse potential are classified as Schedule II drugs
tr tr tr tr tr tr tr tr tr tr tr
because of severe dependence liability. Schedule I drugs have high abuse
tr tr tr tr tr tr tr tr tr tr tr
potential and no accepted medical use. Schedule III drugs have a lesser
tr tr tr tr tr tr tr tr tr tr tr tr
abuse potential than II and an accepted medical use. Schedule IV drugs
tr tr tr tr tr tr tr tr tr tr tr tr
havel ow abuse potential and limited dependence liability.
tr tr tr tr tr tr tr tr
4. What concept is considered when generic drugs are substituted for
tr tr tr tr tr tr tr tr tr
brand name drugs?
tr tr tr
A) Bioavailability
, Page 5 of 822 tr tr tr
B) Critical concentration tr
C) Distribution
D) Half-life
ACCURATE CHOICE:-A
tr
Reasoning:->>>>>>
Bioavailability is the portion of a dose of a drug that reaches the systemic tr tr tr tr tr tr tr tr tr tr tr tr tr
circulation and is available to act on body cells. Binders used in a generic
tr tr tr tr tr tr tr tr tr tr tr tr tr tr
drug may not be the same as those used in the brand name drug.
tr tr tr tr tr tr tr tr tr tr tr tr tr tr
Therefore, the way the body breaks down and uses the drug may differ,
tr tr tr tr tr tr tr tr tr tr tr tr tr
which may eliminate a generic drug substitution. Critical concentration is
tr tr tr tr tr tr tr tr tr tr
the amount ofa drug that is needed to cause a therapeutic effect and
tr tr tr tr tr tr tr tr tr tr tr tr tr tr
should not differ between generic and brand name medications.
tr tr tr tr tr tr tr tr tr
Distribution is the phase of pharmacokinetics, which involves the
tr tr tr tr tr tr tr tr tr
movement of a drug to the bodys tissues and is the same in generic and
tr tr tr tr tr tr tr tr tr tr tr tr tr tr tr
brand name drugs. A drugs half-life ist he time it takes for the amount of
tr tr tr tr tr tr tr tr tr tr tr tr tr tr tr
drug to decrease to half the peak level, which should not change when
tr tr tr tr tr tr tr tr tr tr tr tr tr
substituting a generic medication.
tr tr tr t r
5. A nursing attendant is assessing the hospital clients home medication use. After
tr tr tr tr tr tr tr tr tr tr tr
listening to the hospital client list current medications, the nursing
tr tr tr tr tr tr tr tr tr
attendant askswhat priority question?
tr tr tr tr tr
A) Do you take any generic medications?
tr tr tr tr tr
B) Are any of these medications orphan drugs?
tr tr tr tr tr tr
C) Are these medications safe to take during pregnancy?
tr tr tr tr tr tr tr
D) Do you take any over-the-counter medications?
tr tr tr tr tr
ACCURATE CHOICE:-tr D
Reasoning:->>>>>>
It is important for the nursing attendant to specifically question use of
tr tr tr tr tr tr tr tr tr tr tr
over- the-counter medications because hospital clients may not consider
tr tr tr tr tr tr tr tr tr
them important. The hospital client is unlikely to know the meaning of
tr tr tr tr tr tr tr tr tr tr tr tr
orphan drugs unless they too are primary health care providers. Safety
tr tr tr tr tr tr tr tr tr tr tr
during pregnancy, use of a genericmedication, or classification of orphan
tr tr tr tr tr tr tr tr tr tr tr
drugs are things the hospital client would be unable to answer but could
tr tr tr tr tr tr tr tr tr tr tr tr tr
be found in reference books if the nursing attendant wishes to research
tr tr tr tr tr tr tr tr tr tr tr tr
them.
tr
tr tr tr tr tr
PHARMACOLOGY16TH EDITION KATZUNG’S TESTBANK
tr rt tr tr tr
/ALL CHS 1-
tr tr tr
66/COMPLETE GUIDE 2024-2025 tr tr
,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
tr tr tr tr tr tr tr tr tr tr tr
1. A nurse working in radiology administers iodine to a hospital client who
tr tr tr tr tr tr tr tr tr tr tr
is having a computed tomography (CT) scan. The nursing attendant
tr tr tr tr tr tr tr tr tr tr
working on the oncology unit administers chemotherapy to hospital
tr tr tr tr tr tr tr tr tr
clients who have cancer. At the Public Health Department, a nursing
tr tr tr tr tr tr tr tr tr tr tr
attendant administers a measles-mumps-r ubella (MMR) vaccine to a 14-
tr tr tr tr tr tr tr tr tr tr
month-old child as a routine immunization. Which branch of
tr tr tr tr tr tr tr tr
pharmacology best describes the actions of all three
tr tr tr tr tr tr tr tr
nursing attendants? tr
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- tr B
Reasoning :->>>>>> tr
Pharmacology is the study of the biologic effects of chemicals. Nursing tr tr tr tr tr tr tr tr tr tr
attendants are involved with clinical pharmacology or
tr tr tr tr tr tr tr
pharmacotherapeutics, which is a branch of pharmacology that deals with
tr tr tr tr tr tr tr tr tr tr
the uses of drugs to treat,prevent, and diagnose disease. The radiology
tr tr tr tr tr tr tr tr tr tr tr tr
nursing attendant is administering a drug to help diagnose a disease. The
tr tr tr tr tr tr tr tr tr tr tr tr
oncology nursing attendant is administering a drug to help treat a disease.
tr tr tr tr tr tr tr tr tr tr tr tr
Pharmacoeconomics includes any costs involved in drug therapy.
tr tr tr tr tr tr tr tr
Pharmacodynamics involves how a drug affects the body and tr tr tr tr tr tr tr tr
pharmacokinetics is how the body acts on the body. tr tr tr tr tr tr tr tr
2. When involved in phase III drug evaluation studies,
tr tr tr tr tr tr tr
whatr esponsibilities would the nursing attendant have?
tr tr tr tr tr tr tr
A) Working with animals who are given experimental drugs
tr tr tr tr tr tr tr
B) Choosing appropriate hospital clients to be involved in the drug study
tr tr tr tr tr tr tr tr tr t r
C) Monitoring and observing hospital clients closely for adverse effects
tr tr tr tr tr tr tr tr
D) Conducting research to determine effectiveness of the drug tr tr tr tr tr tr tr
,ACCURATE CHOICE:- tr C
Reasoning:->>>>>>
Phase III studies involve use of a drug in a vast clinical population in
tr tr tr tr tr tr tr tr tr tr tr tr tr
whichhospital clients are asked to record any symptoms they experience
tr tr tr tr tr tr tr tr tr tr tr
while taking the drugs. Nursing attendants may be responsible for helping
tr tr tr tr tr tr tr tr tr tr tr
collect and analyzet he information to be shared with the Food and Drug
tr tr tr tr tr tr tr tr tr tr tr tr tr
Administration (FDA)but would not conduct research independently
tr tr tr tr tr tr tr tr
because nursing attendants donot prescribe medications. Use of animals
tr tr tr tr tr tr tr tr tr tr
in drug testing is done in the preclinical trials. Select hospital clients who
tr tr tr tr tr tr tr tr tr tr tr tr tr
are involved in phase II studies to participate in studies where the
tr tr tr tr tr tr tr tr tr tr tr tr
participants have the disease the drug is intended to treat. These hospital
tr tr tr tr tr tr tr tr tr tr tr tr
clients are monitored closely for drug action and adverse effects. Phase I
tr tr tr tr tr tr tr tr tr tr tr tr
studies involve healthy human volunteers who are usually paid for their
tr tr tr tr tr tr tr tr tr tr tr
participation. Nursing attendants may observe for
tr tr tr tr tr tr
adverse effects and toxicity. tr tr tr
3. A physician has ordered intramuscular (IM) injections of morphine, a
tr tr tr tr tr tr tr tr tr
narcotic, every 4 hours as needed for pain in a motor vehicle accident
tr tr tr tr tr tr tr tr tr tr tr tr tr
victim. The nursing attendant is aware this drug has a high abuse potential.
tr tr tr tr tr tr tr tr tr tr tr tr tr
Under what category would morphine be classified?
tr tr tr tr tr tr tr
A) Schedule I tr
B) Schedule II tr
C) Schedule III tr
D) Schedule IV tr
ACCURATE CHOICE:- tr B
Reasoning:->>>>>>
Narcotics with a high abuse potential are classified as Schedule II drugs
tr tr tr tr tr tr tr tr tr tr tr
because of severe dependence liability. Schedule I drugs have high abuse
tr tr tr tr tr tr tr tr tr tr tr
potential and no accepted medical use. Schedule III drugs have a lesser
tr tr tr tr tr tr tr tr tr tr tr tr
abuse potential than II and an accepted medical use. Schedule IV drugs
tr tr tr tr tr tr tr tr tr tr tr tr
havel ow abuse potential and limited dependence liability.
tr tr tr tr tr tr tr tr
4. What concept is considered when generic drugs are substituted for
tr tr tr tr tr tr tr tr tr
brand name drugs?
tr tr tr
A) Bioavailability
, Page 5 of 822 tr tr tr
B) Critical concentration tr
C) Distribution
D) Half-life
ACCURATE CHOICE:-A
tr
Reasoning:->>>>>>
Bioavailability is the portion of a dose of a drug that reaches the systemic tr tr tr tr tr tr tr tr tr tr tr tr tr
circulation and is available to act on body cells. Binders used in a generic
tr tr tr tr tr tr tr tr tr tr tr tr tr tr
drug may not be the same as those used in the brand name drug.
tr tr tr tr tr tr tr tr tr tr tr tr tr tr
Therefore, the way the body breaks down and uses the drug may differ,
tr tr tr tr tr tr tr tr tr tr tr tr tr
which may eliminate a generic drug substitution. Critical concentration is
tr tr tr tr tr tr tr tr tr tr
the amount ofa drug that is needed to cause a therapeutic effect and
tr tr tr tr tr tr tr tr tr tr tr tr tr tr
should not differ between generic and brand name medications.
tr tr tr tr tr tr tr tr tr
Distribution is the phase of pharmacokinetics, which involves the
tr tr tr tr tr tr tr tr tr
movement of a drug to the bodys tissues and is the same in generic and
tr tr tr tr tr tr tr tr tr tr tr tr tr tr tr
brand name drugs. A drugs half-life ist he time it takes for the amount of
tr tr tr tr tr tr tr tr tr tr tr tr tr tr tr
drug to decrease to half the peak level, which should not change when
tr tr tr tr tr tr tr tr tr tr tr tr tr
substituting a generic medication.
tr tr tr t r
5. A nursing attendant is assessing the hospital clients home medication use. After
tr tr tr tr tr tr tr tr tr tr tr
listening to the hospital client list current medications, the nursing
tr tr tr tr tr tr tr tr tr
attendant askswhat priority question?
tr tr tr tr tr
A) Do you take any generic medications?
tr tr tr tr tr
B) Are any of these medications orphan drugs?
tr tr tr tr tr tr
C) Are these medications safe to take during pregnancy?
tr tr tr tr tr tr tr
D) Do you take any over-the-counter medications?
tr tr tr tr tr
ACCURATE CHOICE:-tr D
Reasoning:->>>>>>
It is important for the nursing attendant to specifically question use of
tr tr tr tr tr tr tr tr tr tr tr
over- the-counter medications because hospital clients may not consider
tr tr tr tr tr tr tr tr tr
them important. The hospital client is unlikely to know the meaning of
tr tr tr tr tr tr tr tr tr tr tr tr
orphan drugs unless they too are primary health care providers. Safety
tr tr tr tr tr tr tr tr tr tr tr
during pregnancy, use of a genericmedication, or classification of orphan
tr tr tr tr tr tr tr tr tr tr tr
drugs are things the hospital client would be unable to answer but could
tr tr tr tr tr tr tr tr tr tr tr tr tr
be found in reference books if the nursing attendant wishes to research
tr tr tr tr tr tr tr tr tr tr tr tr
them.
tr
