HESI · RN EXIT EXAM
HESI 799 RN Exit Exam
Practice Question Bank
NCLEX-Style Practice Questions with Rationales
Comprehensive Review — 73 Questions with Detailed Rationales
Edition 1 · August 2026
,Table of Contents
1. Instructions for Use 2
2. Practice Questions with Answers & Rationales — HESI 799 RN Exit Exam 2
HESI 799 · RN Exit Exam Page 1
,HESI 799 RN EXIT EXAM PRACTICE GUIDE INSTRUCTIONS & PRACTICE QUESTIONS
How to Use This Guide
Read each stem, choose your answer, then check the rationale directly below it. The correct option is marked, and each
wrong option is explained so you understand why it's wrong — not just that it is. This guide contains 73 questions covering
comprehensive nursing content for the HESI 799 RN Exit Exam.
Category: Comprehensive Nursing — HESI 799 RN Exit Exam
1 The nurse is making a home visit to a male client who is in the moderate stage of Alzheimer's disease. The
client's wife is exhausted and tells the nurse that the family plans to take turns caring for the client in their
home, each keeping him for two weeks at a time. How should the nurse respond?
A Advise the client's spouse to consider inpatient hospice care as an alternative
B Suggest that each rotation last one week, rather than two, to prevent caregiver fatigue
C Use active listening to allow the client and spouse to express their feelings about the plan
D Suggest enrolling the client in adult daycare instead of rotating among family
Why D is correct: Suggesting a viable alternative, such as adult daycare, provides an option to allow the spouse respite
with the least disruption to routines and environment.
A — Hospice is for end-of-life care, not appropriate for moderate Alzheimer's.
B — One-week rotations may be more disruptive and still don't address the core issue.
C — Active listening is important, but the spouse is seeking practical solutions for respite.
2 A young adult male was admitted 36 hours ago for a head injury that occurred as the result of a motorcycle
accident. In the last 4 hours, his urine output has increased to over 200 ml/hr. Before reporting the finding
to the healthcare provider, which intervention should the nurse implement?
A Evaluate the urine osmolality and the serum osmolality values
B Obtain blood pressure and assess for dependent edema
C Measure oral secretions suctioned during last hours
D Obtain capillary blood samples q2 hours for glucose monitoring
Why A is correct: With a known head injury, sudden inadequate secretion of antidiuretic hormone (ADH) can cause
excessive output of diluted urine. Evaluating laboratory results should determine findings of neurogenic diabetes
insipidus (DI), such as low urine osmolarity and normal serum osmolarity, prior to notifying the healthcare provider.
B — Hypotension and tachycardia may occur but do not confirm DI.
C — Oral secretions are not related to DI.
D — Glucose monitoring is not indicated for this finding.
, 3 A male client has received a prescription for orlistat for weight and nutrition management. In addition to
the medication, the client states he plans to take a multivitamin. What teaching should the nurse provide?
A As a nutritional supplement, orlistat already contains all the recommended daily vitamins and minerals
B Multivitamins are contraindicated during treatment with weight-control medications such as orlistat
C Be sure to take the multivitamin and the medication at least two hours apart for best absorption and
effectiveness
D Following a well-balanced diet is a much healthier approach to good nutrition than depending on a
multivitamin
Why C is correct: Orlistat reduces absorption of fat-soluble vitamins (A, D, E, K), so a multivitamin should be taken at
least 2 hours apart from the medication.
A — Orlistat does not contain vitamins.
B — Multivitamins are not contraindicated; they are recommended.
D — While diet is important, supplementation is still recommended with orlistat.
4 A female client is taking alendronate, a bisphosphonate, for postmenopausal osteoporosis. The client tells
the nurse that she is experiencing jaw pain. How should the nurse respond?
A Determine how the client is administering the medication
B Confirm that this is a common symptom of osteoporosis
C Report the client's jaw pain to the healthcare provider
D Advise the client to gargle with warm salt water twice daily
Why C is correct: Bisphosphonates, including alendronate, can cause osteonecrosis of the jaw, which should be reported
to the healthcare provider for evaluation.
A — Incorrect administration can cause esophageal reactions, not jaw pain.
B — Jaw pain is not a symptom of osteoporosis.
D — Salt water gargles do not address osteonecrosis.
HESI 799 RN Exit Exam
Practice Question Bank
NCLEX-Style Practice Questions with Rationales
Comprehensive Review — 73 Questions with Detailed Rationales
Edition 1 · August 2026
,Table of Contents
1. Instructions for Use 2
2. Practice Questions with Answers & Rationales — HESI 799 RN Exit Exam 2
HESI 799 · RN Exit Exam Page 1
,HESI 799 RN EXIT EXAM PRACTICE GUIDE INSTRUCTIONS & PRACTICE QUESTIONS
How to Use This Guide
Read each stem, choose your answer, then check the rationale directly below it. The correct option is marked, and each
wrong option is explained so you understand why it's wrong — not just that it is. This guide contains 73 questions covering
comprehensive nursing content for the HESI 799 RN Exit Exam.
Category: Comprehensive Nursing — HESI 799 RN Exit Exam
1 The nurse is making a home visit to a male client who is in the moderate stage of Alzheimer's disease. The
client's wife is exhausted and tells the nurse that the family plans to take turns caring for the client in their
home, each keeping him for two weeks at a time. How should the nurse respond?
A Advise the client's spouse to consider inpatient hospice care as an alternative
B Suggest that each rotation last one week, rather than two, to prevent caregiver fatigue
C Use active listening to allow the client and spouse to express their feelings about the plan
D Suggest enrolling the client in adult daycare instead of rotating among family
Why D is correct: Suggesting a viable alternative, such as adult daycare, provides an option to allow the spouse respite
with the least disruption to routines and environment.
A — Hospice is for end-of-life care, not appropriate for moderate Alzheimer's.
B — One-week rotations may be more disruptive and still don't address the core issue.
C — Active listening is important, but the spouse is seeking practical solutions for respite.
2 A young adult male was admitted 36 hours ago for a head injury that occurred as the result of a motorcycle
accident. In the last 4 hours, his urine output has increased to over 200 ml/hr. Before reporting the finding
to the healthcare provider, which intervention should the nurse implement?
A Evaluate the urine osmolality and the serum osmolality values
B Obtain blood pressure and assess for dependent edema
C Measure oral secretions suctioned during last hours
D Obtain capillary blood samples q2 hours for glucose monitoring
Why A is correct: With a known head injury, sudden inadequate secretion of antidiuretic hormone (ADH) can cause
excessive output of diluted urine. Evaluating laboratory results should determine findings of neurogenic diabetes
insipidus (DI), such as low urine osmolarity and normal serum osmolarity, prior to notifying the healthcare provider.
B — Hypotension and tachycardia may occur but do not confirm DI.
C — Oral secretions are not related to DI.
D — Glucose monitoring is not indicated for this finding.
, 3 A male client has received a prescription for orlistat for weight and nutrition management. In addition to
the medication, the client states he plans to take a multivitamin. What teaching should the nurse provide?
A As a nutritional supplement, orlistat already contains all the recommended daily vitamins and minerals
B Multivitamins are contraindicated during treatment with weight-control medications such as orlistat
C Be sure to take the multivitamin and the medication at least two hours apart for best absorption and
effectiveness
D Following a well-balanced diet is a much healthier approach to good nutrition than depending on a
multivitamin
Why C is correct: Orlistat reduces absorption of fat-soluble vitamins (A, D, E, K), so a multivitamin should be taken at
least 2 hours apart from the medication.
A — Orlistat does not contain vitamins.
B — Multivitamins are not contraindicated; they are recommended.
D — While diet is important, supplementation is still recommended with orlistat.
4 A female client is taking alendronate, a bisphosphonate, for postmenopausal osteoporosis. The client tells
the nurse that she is experiencing jaw pain. How should the nurse respond?
A Determine how the client is administering the medication
B Confirm that this is a common symptom of osteoporosis
C Report the client's jaw pain to the healthcare provider
D Advise the client to gargle with warm salt water twice daily
Why C is correct: Bisphosphonates, including alendronate, can cause osteonecrosis of the jaw, which should be reported
to the healthcare provider for evaluation.
A — Incorrect administration can cause esophageal reactions, not jaw pain.
B — Jaw pain is not a symptom of osteoporosis.
D — Salt water gargles do not address osteonecrosis.
