ATI TEAS Test – Science Section
Advanced Practice Question Bank
V2.0 (150 New Questions with
Detailed Rationales)
Table of Contents
Question
Section Topic Area
Numbers
Advanced Cardiovascular, Respiratory, & Renal-Integrated
I 1–25
Physiology
Advanced Neuromuscular, Endocrine, & Thermoregulatory
II 26–50
Dynamics
Advanced Digestive, Hepatic, & Metabolic Pathway
III 51–75
Integration
Reproductive Immunology, Integumentary Pathology, &
IV 76–100
Fluid Balance
Cellular Biology – Organelle Trafficking, Membrane
V 101–120
Transport & Signaling
, Question
Section Topic Area
Numbers
Genetics – Advanced Mendelian Genetics, Epigenetics, &
VI 121–135
DNA Repair
Chemistry – Stoichiometry, Thermodynamics, & Acid-Base
VII 136–145
Titrations
Scientific Reasoning – Complex Experimental Design & Data
VIII 146–150
Analysis
SECTION I: Advanced Cardiovascular, Respiratory, & Renal-Integrated Physiology
Question 1
The Frank-Starling law of the heart states that the stroke volume increases in direct proportion
to:
A) The afterload pressure in the aorta
B) The end-diastolic volume (preload) of the ventricles
C) The heart rate measured in beats per minute
D) The contractility mediated by sympathetic stimulation
CorreCt Answer: B
Rationale: The Frank-Starling law states that the more the heart muscle is stretched during
diastole (increased end-diastolic volume/preload), the greater the force of contraction and
subsequent stroke volume, assuming all other factors are constant.
Question 2
During the isovolumetric contraction phase of the cardiac cycle, which of the following events
occurs?
A) The AV valves and semilunar valves are all closed
B) Blood is forcefully ejected into the aorta
C) The ventricles are passively filling with blood
D) The atria contract to force blood into the ventricles
CorreCt Answer: A
,Rationale: During isovolumetric contraction, the ventricles begin contracting with all four valves
closed, increasing pressure without volume change. The semilunar valves open only when
ventricular pressure exceeds aortic/pulmonary pressure.
Question 3
A patient has a mean arterial pressure (MAP) of 60 mm Hg. Which of the following conditions is
most likely occurring?
A) Adequate perfusion of vital organs
B) Onset of tissue ischemia due to inadequate perfusion
C) Hypertension causing left ventricular hypertrophy
D) Normal resting cardiovascular function
CorreCt Answer: B
Rationale: Normal MAP is 70–105 mm Hg. A MAP below 60 mm Hg indicates inadequate
perfusion, leading to ischemia of vital organs like the brain and kidneys.
Question 4
Which of the following accurately describes the partial pressure gradients driving gas exchange
in the pulmonary capillaries?
A) PO₂ is higher in the alveoli than in the pulmonary capillary blood
B) PCO₂ is higher in the alveoli than in the pulmonary capillary blood
C) PO₂ is equal between alveoli and pulmonary capillary blood
D) PCO₂ is higher in the inspired air than in the alveoli
CorreCt Answer: A
Rationale: Oxygen diffuses from the alveoli (PO₂ ≈ 100 mm Hg) into the pulmonary capillary
blood (PO₂ ≈ 40 mm Hg) down its concentration gradient. CO₂ diffuses in the opposite direction
because alveolar PCO₂ is lower than capillary PCO₂.
Question 5
The juxtaglomerular apparatus in the kidney responds to decreased renal blood pressure by
releasing which substance that ultimately leads to increased blood pressure?
A) Antidiuretic hormone (ADH)
B) Atrial natriuretic peptide (ANP)
C) Renin, which initiates the angiotensin-aldosterone pathway
D) Epinephrine
, CorreCt Answer: C
Rationale: Decreased renal perfusion stimulates the JG apparatus to release renin, which
converts angiotensinogen to angiotensin I, then to angiotensin II, causing vasoconstriction and
aldosterone release to increase blood volume/pressure.
Question 6
In the nephron, the descending limb of the loop of Henle is permeable to water but NOT to
solutes, while the ascending limb is impermeable to water but actively transports sodium and
chloride out. This countercurrent multiplier system primarily functions to:
A) Filter blood plasma into the Bowman's capsule
B) Reabsorb glucose and amino acids
C) Establish a concentration gradient in the renal medulla for water reabsorption
D) Secretion of hydrogen ions and potassium
CorreCt Answer: C
Rationale: The countercurrent multiplier creates a high osmotic gradient in the medulla,
allowing the collecting duct to reabsorb water under ADH influence, concentrating urine.
Question 7
The presence of a large QRS complex on an electrocardiogram (ECG) followed immediately by a
prolonged QT interval would indicate which of the following?
A) Normal sinus rhythm
B) Delayed ventricular repolarization, increasing risk of arrhythmias
C) Atrial fibrillation
D) First-degree AV block (prolonged PR interval)
CorreCt Answer: B
Rationale: The QT interval represents ventricular depolarization and repolarization. A prolonged
QT indicates delayed repolarization, predisposing to torsades de pointes and ventricular
arrhythmias.
Question 8
Which of the following correctly pairs the respiratory volume with its definition?
A) Tidal Volume (TV) – maximum air that can be exhaled after a maximal inhalation
B) Inspiratory Reserve Volume (IRV) – extra air inhaled beyond a normal tidal breath
C) Residual Volume (RV) – air that can be forcibly exhaled after normal exhalation
Advanced Practice Question Bank
V2.0 (150 New Questions with
Detailed Rationales)
Table of Contents
Question
Section Topic Area
Numbers
Advanced Cardiovascular, Respiratory, & Renal-Integrated
I 1–25
Physiology
Advanced Neuromuscular, Endocrine, & Thermoregulatory
II 26–50
Dynamics
Advanced Digestive, Hepatic, & Metabolic Pathway
III 51–75
Integration
Reproductive Immunology, Integumentary Pathology, &
IV 76–100
Fluid Balance
Cellular Biology – Organelle Trafficking, Membrane
V 101–120
Transport & Signaling
, Question
Section Topic Area
Numbers
Genetics – Advanced Mendelian Genetics, Epigenetics, &
VI 121–135
DNA Repair
Chemistry – Stoichiometry, Thermodynamics, & Acid-Base
VII 136–145
Titrations
Scientific Reasoning – Complex Experimental Design & Data
VIII 146–150
Analysis
SECTION I: Advanced Cardiovascular, Respiratory, & Renal-Integrated Physiology
Question 1
The Frank-Starling law of the heart states that the stroke volume increases in direct proportion
to:
A) The afterload pressure in the aorta
B) The end-diastolic volume (preload) of the ventricles
C) The heart rate measured in beats per minute
D) The contractility mediated by sympathetic stimulation
CorreCt Answer: B
Rationale: The Frank-Starling law states that the more the heart muscle is stretched during
diastole (increased end-diastolic volume/preload), the greater the force of contraction and
subsequent stroke volume, assuming all other factors are constant.
Question 2
During the isovolumetric contraction phase of the cardiac cycle, which of the following events
occurs?
A) The AV valves and semilunar valves are all closed
B) Blood is forcefully ejected into the aorta
C) The ventricles are passively filling with blood
D) The atria contract to force blood into the ventricles
CorreCt Answer: A
,Rationale: During isovolumetric contraction, the ventricles begin contracting with all four valves
closed, increasing pressure without volume change. The semilunar valves open only when
ventricular pressure exceeds aortic/pulmonary pressure.
Question 3
A patient has a mean arterial pressure (MAP) of 60 mm Hg. Which of the following conditions is
most likely occurring?
A) Adequate perfusion of vital organs
B) Onset of tissue ischemia due to inadequate perfusion
C) Hypertension causing left ventricular hypertrophy
D) Normal resting cardiovascular function
CorreCt Answer: B
Rationale: Normal MAP is 70–105 mm Hg. A MAP below 60 mm Hg indicates inadequate
perfusion, leading to ischemia of vital organs like the brain and kidneys.
Question 4
Which of the following accurately describes the partial pressure gradients driving gas exchange
in the pulmonary capillaries?
A) PO₂ is higher in the alveoli than in the pulmonary capillary blood
B) PCO₂ is higher in the alveoli than in the pulmonary capillary blood
C) PO₂ is equal between alveoli and pulmonary capillary blood
D) PCO₂ is higher in the inspired air than in the alveoli
CorreCt Answer: A
Rationale: Oxygen diffuses from the alveoli (PO₂ ≈ 100 mm Hg) into the pulmonary capillary
blood (PO₂ ≈ 40 mm Hg) down its concentration gradient. CO₂ diffuses in the opposite direction
because alveolar PCO₂ is lower than capillary PCO₂.
Question 5
The juxtaglomerular apparatus in the kidney responds to decreased renal blood pressure by
releasing which substance that ultimately leads to increased blood pressure?
A) Antidiuretic hormone (ADH)
B) Atrial natriuretic peptide (ANP)
C) Renin, which initiates the angiotensin-aldosterone pathway
D) Epinephrine
, CorreCt Answer: C
Rationale: Decreased renal perfusion stimulates the JG apparatus to release renin, which
converts angiotensinogen to angiotensin I, then to angiotensin II, causing vasoconstriction and
aldosterone release to increase blood volume/pressure.
Question 6
In the nephron, the descending limb of the loop of Henle is permeable to water but NOT to
solutes, while the ascending limb is impermeable to water but actively transports sodium and
chloride out. This countercurrent multiplier system primarily functions to:
A) Filter blood plasma into the Bowman's capsule
B) Reabsorb glucose and amino acids
C) Establish a concentration gradient in the renal medulla for water reabsorption
D) Secretion of hydrogen ions and potassium
CorreCt Answer: C
Rationale: The countercurrent multiplier creates a high osmotic gradient in the medulla,
allowing the collecting duct to reabsorb water under ADH influence, concentrating urine.
Question 7
The presence of a large QRS complex on an electrocardiogram (ECG) followed immediately by a
prolonged QT interval would indicate which of the following?
A) Normal sinus rhythm
B) Delayed ventricular repolarization, increasing risk of arrhythmias
C) Atrial fibrillation
D) First-degree AV block (prolonged PR interval)
CorreCt Answer: B
Rationale: The QT interval represents ventricular depolarization and repolarization. A prolonged
QT indicates delayed repolarization, predisposing to torsades de pointes and ventricular
arrhythmias.
Question 8
Which of the following correctly pairs the respiratory volume with its definition?
A) Tidal Volume (TV) – maximum air that can be exhaled after a maximal inhalation
B) Inspiratory Reserve Volume (IRV) – extra air inhaled beyond a normal tidal breath
C) Residual Volume (RV) – air that can be forcibly exhaled after normal exhalation
