MCB 150 SECTION 1 2026 ENZYMES AND
BASIC METABOLISM PROCESSES
PROFESSIONAL GUIDE
◉ Virulence factor Plasmodium falciparum (protozoan)
Answer: Antigenic variation. Adhesion membrane protein called
PfEMP1. RBC stick together stop blood flow
malaria
◉ Virulence factor Trypanosoma Brucei (protozoan)
Answer: Capsules and antigenic variations
African Sleeping Sickness
◉ Virulence factors with Helminths
Answer: Parasitic worms
large and evade immune system
roundworms protected by tough outer cuticle
glycan "Gimmickry" resembles host cells, immune system fails to
recognize the attack
suppress immune system or make the immune system respond
inappropriately
, ◉ Bacteremia
Answer: bacteria in the blood
◉ septicemia
Answer: growth of bacteria in the blood and multiplying
◉ Viremia
Answer: viruses in the blood
◉ Toxemia
Answer: toxins in the blood
◉ Exoenzymes
Answer: Produced by pathogens that enable them to invade host
cells and deeper tissues
◉ function of glycohydrolases (exoenzymes)
Answer: Degrades hyaluronic acid that cements cells together to
promote spreading through tissues
Ex: Hyaluronidase S in staph aureus
◉ Function of nucleuses (exoenzyme)
BASIC METABOLISM PROCESSES
PROFESSIONAL GUIDE
◉ Virulence factor Plasmodium falciparum (protozoan)
Answer: Antigenic variation. Adhesion membrane protein called
PfEMP1. RBC stick together stop blood flow
malaria
◉ Virulence factor Trypanosoma Brucei (protozoan)
Answer: Capsules and antigenic variations
African Sleeping Sickness
◉ Virulence factors with Helminths
Answer: Parasitic worms
large and evade immune system
roundworms protected by tough outer cuticle
glycan "Gimmickry" resembles host cells, immune system fails to
recognize the attack
suppress immune system or make the immune system respond
inappropriately
, ◉ Bacteremia
Answer: bacteria in the blood
◉ septicemia
Answer: growth of bacteria in the blood and multiplying
◉ Viremia
Answer: viruses in the blood
◉ Toxemia
Answer: toxins in the blood
◉ Exoenzymes
Answer: Produced by pathogens that enable them to invade host
cells and deeper tissues
◉ function of glycohydrolases (exoenzymes)
Answer: Degrades hyaluronic acid that cements cells together to
promote spreading through tissues
Ex: Hyaluronidase S in staph aureus
◉ Function of nucleuses (exoenzyme)
