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RN Pharmacology Latest 2026 Actual Exam | 242 Q&A with Rationales | NCLEX Pharmacology Review

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Pass your RN Pharmacology exam and NCLEX-RN on your first attempt with this comprehensive Q-Bank featuring 242 actual exam questions with verified correct answers and detailed rationales. This document covers essential pharmacology topics including Medication Administration, Dosage Calculations, Cardiovascular Drugs, CNS Medications, Antibiotics, Anticoagulants, Antidiabetic Agents, Chemotherapy, Immunizations, and Herbal Supplements. Each question includes in-depth rationales to reinforce understanding of drug actions, side effects, adverse reactions, and nursing interventions. Perfect for nursing students, NCLEX-RN candidates, and RN pharmacology exam preparation.

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RN Pharmacology LATEST 2024 ACTUAL EXAM 242 QUESTIONS AND
ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |ALREADY GRADE A+


1. A provider prescribes phenobarbital for a client who has a seizure disorder.
The medication has a long half-life of 4 days. How many times per day should
the nurse expect to administer this medication?

A. One

B. Two

C. Three

D. Four: A. Medications with long half-lives remain at their therapeutic levels
between doses for long periods of time. The nurse should expect to administer
this medication once a day.
2. A staff educator is reviewing medication dosages and factors that influence
medication metabolism with a group of nurses at an in-service presentation.
Which of the following factors should the educator include as a reason to
administer lower medication dosages? (Select all that apply.)

A. Increased renal secretion

B. Increased medication-metabolizing enzymes

C. Liver failure

D. Peripheral vascular disease

E. Concurrent use of medication the same pathway metabolizes: Answer:

C. Liver failure decreases metabolism and thus increases the concentration of a
medication. This requires decreasing the dosage.

E. When the same pathway metabolizes two medications, they compete for
metabolism, thereby increasing the concentration of one or both medications. This
requires decreasing the dosage of one or both medications.
3. A nurse is preparing to
administer eye drops to a client.
Which of the following actions


,RN Pharmacology LATEST 2024 ACTUAL EXAM 242 QUESTIONS AND
ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |ALREADY GRADE A+


should the nurse take? (Select all
that apply.)

A. have the client lie on her side.

B. Ask the client to look
up at the ceiling.

C. Tell the client to blink when the drops enter her eye.

D. Drop the medication
into the center of the
client's conjunctival sac.

E. Instruct the client to close her eye gently after instillation: B. The client
should look upward to keep the drops from falling onto her cornea.
D. The nurse should drop the medication into
the center of the conjunctival sac to promote
distribution.

E. The client should close her eye gently to
promote distribution of the medication
4. A nurse is completing discharge teaching for a client who has a new
prescription for transdermal patches. Which of the following
statements should the nurse identify as an indication that the client
understands the instructions?

A. "I will clean the site with
an alcohol swab before I
apply the patch."

B. "I will rotate the application sites weekly."

C. "I will apply the patch to an area of skin with no hair."





,RN Pharmacology LATEST 2024 ACTUAL EXAM 242 QUESTIONS AND
ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |ALREADY GRADE A+


D. "I will place the new patch on the site of the old patch.: C. The client
should apply the patch to a hairless area of skin to promote absorption of the
medication.
5. A nurse reviewing a client's
medical record notes a new prescription for verifying the trough

level of the client's medication. Which of the following actions should the
nurse take?

A. Obtain a blood specimen
immediately prior to
administering the next dose
of medication.

B. Verify that the client has
been taking the medication
for 24 hr before obtaining
a blood specimen.

C. Ask the client to pr ovide a urine specimen after the
next dose of medication.

D. Administer the medication,and obtain a blood specimen 30 min late: A.
To verify trough levels of a medication, the nurse should obtain a blood
specimen immediately before administering the next dose of medication.
6. A nurse is preparing a client's medications. Which of the following
actions should the nurse take in following legal practice guidelines? (Select
all that apply.)

A. maintain skill competency.

B.Determine the dosage.

C. monitor for adverse effects.

D. Safeguard medications.


, RN Pharmacology LATEST 2024 ACTUAL EXAM 242 QUESTIONS AND
ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |ALREADY GRADE A+


E. Identify the client's diagnosis: A.maintaining skill competency and using
appropriate administration techniques are legal responsibilities of the nurse

C. A nurse is legally responsible for monitoring for
side and adverse effects of medication
D. Safeguarding of medications, such as controlled
substances, is a legal responsibility of the nurse
7. A nurse reviewing a client's health record notes a new prescription for
lisinopril 10 mg PO once every day. The nurse should identify this as which
of the following types of prescription?

A.Single

B.Stat

C.Routine

D.Standing: C. A routine or standard prescription identifies
medications to give on a regular schedule with or without a termination
date or a specific number of doses. The nurse will administer this
medication every day until the provider discontinues it.
8. A nurse is reviewing a new prescription for ondansetron 4 mg
PO PRN for nausea and vomiting for a client who has hyperemesis
gravidarum. The nurse should clarify which of the following parts of the
prescription with the provider?

A. Name

B.Dosage

C.Route

D.Frequency: D. This prescription does not include the time or frequency of
medication administration. The nurse must clarify this with the prescribing provide
9. A nurse is admitting a client and completing a preassessment before
administering medications. Which of the following data should the nurse
include in the preassessment? (Select all that apply.)

Información del documento

Subido en
18 de agosto de 2026
Número de páginas
113
Escrito en
2026/2027
Tipo
Examen
Contiene
Preguntas y respuestas
$21.99

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