RODAK'S HEMATOLOGY - SIXTH
EDITION QUESTIONS AND ANSWERS
Which9of9the9following9inherited9leukocyte9disorders9is9caused9by9a9mutation9in
9the9lami9B9receptor?
a.9Pelgar-Huet9anomaly
b.9Chediak-Higashi9disease
c.9Alder-Reilly9anomaly
d.9May-Hegglin9anomaly9-9ans-A
which9of9the9following9inherited9leukocyte9disorders9involves9mutations9in9non9
muscle9myosin9heavy9chain9IIA?
a.9Pelgar-Huet9anomaly
b.9Chediak-Higashi9disease
c.9Alder-Reilly9anomaly
d.9May-Hegglin9anomaly9-9ans-D
which9of9the9following9inherited9leukocyte9disorders9might9be9seen9in9Hurler9sy
ndrome?
a.9Pelgar-Huet9anomaly
b.9Chediak-Higashi9disease
c.9Alder-Reilly9anomaly
d.9May-Hegglin9anomaly9-9ans-C
which9of9the9following9lysosomal9storage9diseases9is9characterized9by9macroph
ages9with9striated9cytoplasm9and9storage9of9glucocerbroside?
a.9sanfilippo9syndrome
b.9Gaucher9disease
c.9Fabry9disease
d.9Riemann-Pick9disease9-9ans-B
the9neutrophils9in9CGD9are9incapable9of9producing
a.9hydrogen9peroxide
b.9hypochlorite
c.9superoxide
, d.9all9of9the9above9-9ans-D
Individuals9with9X-
linked9SCID9have9a9mutation9that9affects9their9ability9to9synthesize
a.9Deaminase
b.9Oxidase
c.9IL-29receptor
d.9IL-89receptor9-9ans-C
An9absolute9lymphocytosis9with9reactive9lymphocytes9suggests9which9of9the9foll
owing9conditions?
a.9DiGeorge9syndrome
b.9Bacterial9infection
c.9Parasitic9infection
d.9Viral9infection9-9ans-D
what9leukocyte9cytoplasmic9inclusion9is9composed9of9ribosomal9RNA?
a.9Primary9granules
b.9toxic9granules
c.9dohle9bodies
d.9Howell-jolly9bodies9-9ans-C
the9expected9CBC9results9for9women9in9active9labor9would9include:
a.9high9total9WBC9count9with9increased9lymphocytes
b.9High9total9WBC9count9with9a9slight9shift9to9the9left9in9neutrophils
c.9Normal9WBC9count9with9increased9eosinophils
d.9Low9WBC9count9with9increased9monocytes9-9ans-B
which9of9the9following9is9true9of9an9absolute9increase9in9lymphocytes9with9reac
tive9morphology?
a.9the9population9of9lymphocytes9appears9morphologically9homogenous
b.9they9are9usually9effector9B9cells
c.9the9reactive9lymphocytes9have9increased9cytoplasm9with9variable9basophilia
d.9they9are9most9commonly9seen9in9bacterial9infections9-9ans-C
Lymphomas9differ9from9leukemias9in9that9they9are:
a.9solid9tumors
b.9not9considered9systemic9diseases
c.9never9found9in9peripheral9blood
d.9do9not9originate9from9hematopoietic9cells9-9ans-A
EDITION QUESTIONS AND ANSWERS
Which9of9the9following9inherited9leukocyte9disorders9is9caused9by9a9mutation9in
9the9lami9B9receptor?
a.9Pelgar-Huet9anomaly
b.9Chediak-Higashi9disease
c.9Alder-Reilly9anomaly
d.9May-Hegglin9anomaly9-9ans-A
which9of9the9following9inherited9leukocyte9disorders9involves9mutations9in9non9
muscle9myosin9heavy9chain9IIA?
a.9Pelgar-Huet9anomaly
b.9Chediak-Higashi9disease
c.9Alder-Reilly9anomaly
d.9May-Hegglin9anomaly9-9ans-D
which9of9the9following9inherited9leukocyte9disorders9might9be9seen9in9Hurler9sy
ndrome?
a.9Pelgar-Huet9anomaly
b.9Chediak-Higashi9disease
c.9Alder-Reilly9anomaly
d.9May-Hegglin9anomaly9-9ans-C
which9of9the9following9lysosomal9storage9diseases9is9characterized9by9macroph
ages9with9striated9cytoplasm9and9storage9of9glucocerbroside?
a.9sanfilippo9syndrome
b.9Gaucher9disease
c.9Fabry9disease
d.9Riemann-Pick9disease9-9ans-B
the9neutrophils9in9CGD9are9incapable9of9producing
a.9hydrogen9peroxide
b.9hypochlorite
c.9superoxide
, d.9all9of9the9above9-9ans-D
Individuals9with9X-
linked9SCID9have9a9mutation9that9affects9their9ability9to9synthesize
a.9Deaminase
b.9Oxidase
c.9IL-29receptor
d.9IL-89receptor9-9ans-C
An9absolute9lymphocytosis9with9reactive9lymphocytes9suggests9which9of9the9foll
owing9conditions?
a.9DiGeorge9syndrome
b.9Bacterial9infection
c.9Parasitic9infection
d.9Viral9infection9-9ans-D
what9leukocyte9cytoplasmic9inclusion9is9composed9of9ribosomal9RNA?
a.9Primary9granules
b.9toxic9granules
c.9dohle9bodies
d.9Howell-jolly9bodies9-9ans-C
the9expected9CBC9results9for9women9in9active9labor9would9include:
a.9high9total9WBC9count9with9increased9lymphocytes
b.9High9total9WBC9count9with9a9slight9shift9to9the9left9in9neutrophils
c.9Normal9WBC9count9with9increased9eosinophils
d.9Low9WBC9count9with9increased9monocytes9-9ans-B
which9of9the9following9is9true9of9an9absolute9increase9in9lymphocytes9with9reac
tive9morphology?
a.9the9population9of9lymphocytes9appears9morphologically9homogenous
b.9they9are9usually9effector9B9cells
c.9the9reactive9lymphocytes9have9increased9cytoplasm9with9variable9basophilia
d.9they9are9most9commonly9seen9in9bacterial9infections9-9ans-C
Lymphomas9differ9from9leukemias9in9that9they9are:
a.9solid9tumors
b.9not9considered9systemic9diseases
c.9never9found9in9peripheral9blood
d.9do9not9originate9from9hematopoietic9cells9-9ans-A
