RODAKS HEMATOLOGY 6TH EDITION
EXAM REVIEW TESTED QUESTIONS WITH
100 PERCENT CORRECT ANSWERS
◉ A 20 year old African American man has peripheral blood changes
suggesting thalassemia minor. The quantitative hemoglobin A2 level
is normal but the hemoglobin level is 5% (normal <2%). This is most
consistent with:
a. alpha thalassemia minor
b. beta thalassemia minor
c. delta beta thalassemia minor
d. heriditary persistence of fetal hemoglobin
Answer: c
◉ Anemia secondary to uremia characteristically is:
a. microcytic, hypochromic
b. hemolytic
c. normocytic, normochromic
d. macrocytic
Answer: c
,◉ Which of the following sets of laboratory findings is consistent
with hemolytic anemia?
a. normal or slightly increased erythrocyte survival; normal
reticulocyte count
b. decreased erythrocyte survival: increased catabolism of heme
c. decreased serum lactate dehydrogenase activity; normal
catabolism of heme
d. normal concentration of haptoglobin; marked hemoglobinuriab
Answer: b
◉ An enzyme deficiency associated with a moderate to severe
hemolytic anemia after the patient is exposed to certain drugs and
characterized by red cell inclusions formed by denatured
hemoglobin is?
a. lactate dehydrogenase deficiency
b. G6PD deficiency
c. pyruvate kinase deficiency
d. hexokinase deficiency
Answer: b
◉ Patients with G6PD deficiency are least likely to have hemolytic
episodes in which of the following situations?
a. following the administration of oxidizing drugs
b. following the engestion of fava beans
,c. during infections
d. spontaneously
Answer: d
◉ A patient has a congenital nonspherocytic hemolytic anemia. After
exposure to anti-malaria drugs the patient experiences a severe
hemolytic episode. This episode is characterized by red cells
inclusions caused by hemoglobic denaturation. Which of the
following conditions is most consistent with these findings?
a. G6PD deficiency
b. thalassemia major
c. pyruvate kinase deficiency
d. paroxysmal nocturnal hemoglobinuria
Answer: a
◉ All of the findings listed below may be seen in acquired hemolytic
anemias of the autoimmune variety. The one considered to be the
MOST characteristic is:
a. increased reticulocyte count
b. leukopenia and thrombocytopenia
c. peripheral spherocytosis
d. positive direct antiglobulin test
Answer: d
, ◉ Peripheral blood smears from patients with untreated pernicious
anemia are characterized by:
a. pancytopenia and macrocytosis
b. leukocytosis and elliptocytosis
c. leukocytosis and ovalocytosis
d. pancytopenia and microcytosis
Answer: a
◉ The laboratory tests performed on a patient indicate
macrocytosis, anemia, leukopenia, and thrombocytopenia. Which of
the following disorders is the patient most likely to have?
a. anemia of chronic disease
b. vitamin B12 deficiency
c. iron deficiency
d. acute hemorrhage
Answer: B
◉ The characteristic morphologic feature in folic acid deficiency is:
a. macrocytosis
b. target cells
c. basophilic stippling
EXAM REVIEW TESTED QUESTIONS WITH
100 PERCENT CORRECT ANSWERS
◉ A 20 year old African American man has peripheral blood changes
suggesting thalassemia minor. The quantitative hemoglobin A2 level
is normal but the hemoglobin level is 5% (normal <2%). This is most
consistent with:
a. alpha thalassemia minor
b. beta thalassemia minor
c. delta beta thalassemia minor
d. heriditary persistence of fetal hemoglobin
Answer: c
◉ Anemia secondary to uremia characteristically is:
a. microcytic, hypochromic
b. hemolytic
c. normocytic, normochromic
d. macrocytic
Answer: c
,◉ Which of the following sets of laboratory findings is consistent
with hemolytic anemia?
a. normal or slightly increased erythrocyte survival; normal
reticulocyte count
b. decreased erythrocyte survival: increased catabolism of heme
c. decreased serum lactate dehydrogenase activity; normal
catabolism of heme
d. normal concentration of haptoglobin; marked hemoglobinuriab
Answer: b
◉ An enzyme deficiency associated with a moderate to severe
hemolytic anemia after the patient is exposed to certain drugs and
characterized by red cell inclusions formed by denatured
hemoglobin is?
a. lactate dehydrogenase deficiency
b. G6PD deficiency
c. pyruvate kinase deficiency
d. hexokinase deficiency
Answer: b
◉ Patients with G6PD deficiency are least likely to have hemolytic
episodes in which of the following situations?
a. following the administration of oxidizing drugs
b. following the engestion of fava beans
,c. during infections
d. spontaneously
Answer: d
◉ A patient has a congenital nonspherocytic hemolytic anemia. After
exposure to anti-malaria drugs the patient experiences a severe
hemolytic episode. This episode is characterized by red cells
inclusions caused by hemoglobic denaturation. Which of the
following conditions is most consistent with these findings?
a. G6PD deficiency
b. thalassemia major
c. pyruvate kinase deficiency
d. paroxysmal nocturnal hemoglobinuria
Answer: a
◉ All of the findings listed below may be seen in acquired hemolytic
anemias of the autoimmune variety. The one considered to be the
MOST characteristic is:
a. increased reticulocyte count
b. leukopenia and thrombocytopenia
c. peripheral spherocytosis
d. positive direct antiglobulin test
Answer: d
, ◉ Peripheral blood smears from patients with untreated pernicious
anemia are characterized by:
a. pancytopenia and macrocytosis
b. leukocytosis and elliptocytosis
c. leukocytosis and ovalocytosis
d. pancytopenia and microcytosis
Answer: a
◉ The laboratory tests performed on a patient indicate
macrocytosis, anemia, leukopenia, and thrombocytopenia. Which of
the following disorders is the patient most likely to have?
a. anemia of chronic disease
b. vitamin B12 deficiency
c. iron deficiency
d. acute hemorrhage
Answer: B
◉ The characteristic morphologic feature in folic acid deficiency is:
a. macrocytosis
b. target cells
c. basophilic stippling
