PATHOPHYSIOLOGY HESI (2026/2027)
UPDATE|EXAM
QUESTIONS WITH MULTIPLE
CHOICES |VERIFIED & REVISED
ANSWERS (NEW)!!!
a.mpositivemfeedbackm-
mCORRECTmANSWERmAnminitialmdisturbanceminmamsystemmsetsmoffmamchainmofmeventsmthatmdoesmno
tmfavormstabilitymandmoftenmabruptlymdisplacesmamsystemmfrommitsmsteadymstate:mwhatmismthat?
a.mPositivemFeedback
b.mNegativemFeedback
c.mDisease
d.mHomeostasis
b.mgumsm-mCORRECTmANSWERmWhatmorganmshrinksmwithmage?
a.mProstate
b.mGums
c.mHeart
d.mAllmofmthemabove
d.mtheremismlessmthirstmperceptionminmthemelderlym-
mCORRECTmANSWERmWhichmofmthemfollowingmismtrue?
a.mAnminfantmwillmhavemamslowermheartmratemthanmanmadult
b.mThemelderlymhavembettermtemperaturemsensations
c.mTheremaremmoremsweatmglandsminmanmelderlymperson
d.mTheremismlessmthirstmperceptionminmthemelderly
,c.mWomenmhavemamlowermhemoglobinmthanmmenm-
mCORRECTmANSWERmWhichmofmthemfollowingmismtrue?
a.mWomenmsnoremmoremthanmmen
b.mMenmhavemhighermcalciummlevels
c.mWomenmhavemamlowermhemoglobinmthanmmen
d.mMenmhavemamlowermcreatininemlevelmthanmwomen
b.mAcclimatizationm-
mCORRECTmANSWERmAnmincreaseminmnormalmadaptivemresponsemtomthemdecreasedmavailabilitymof
moxygenmatmhighmaltitudemismtermedmwhich?
a.mCircadian
b.mAcclimatization
c.mPopulation
d.mDiurnal
d.mIatrogenicm-
mCORRECTmANSWERmWhatmdoesmitmmeanmwhenmthemcausemofmthemdiseasemismunwantedmmedicalm
treatment?
a.mIdiopathic
b.mEcogenetic
c.mGenotypical
d.mIatrogenic
d.mNeonatalm-mCORRECTmANSWERmWhichmtermmismusedmformthemfirstmtwommonthsmofmlife?
a.mInfancy
b.mChildhood
c.mPrenatal
,d.mNeonatal
d.mSignm-mCORRECTmANSWERmWhichmismanmobjectivelymidentifiablemaberrationmofmthemdisease?
a.mSymptom
b.mSyndrome
c.mStage
d.mSign
c.mTheymincludemepinephrinemandmnorepinephrinem-
mCORRECTmANSWERmWhichmofmthemfollowingmismtruemregardingmcatecholamines?
a.mTheymaremfrommthemparasympatheticmnervousmsystem
b.mTheymcrossmthembloodmbrainmbarrier
c.mTheymincludemepinephrinemandmnorepinephrine
d.mTheymcausemofmdecreaseminmheartmrate
b.mEndorphinsmincreasemwithmstress,mresultingminmamdecreaseminmpainmperceptionm-
mCORRECTmANSWERmWhichmofmthemfollowingmismamtruemstatement?
a.mAntidiureticmhormonemismnotmimportantmformbloodmvolumemregulation
b.mEndorphinsmincreasemwithmstress,mresultingminmamdecreaseminmpainmperception
c.mEpinephrinemandmcortisolmactmverymdifferently
d.mCortisolmnegatesmepinephrine'smactivity
d.mTheymcrossmbymdiffusionm-
mCORRECTmANSWERmBymwhatmmechanismmdomlipidmmoleculesmcrossmcellmmembranes?
a.mTheymusemchannelmproteinsmasmammembranemtransportmsystem
b.mTheymaremtransportedmacrossmthemplasmammembranembymendocytosismandmexocytosis
c.mTheymusemvoltage-gatedmionmchannels
, d.mTheymcrossmbymdiffusion
a.mProteinmsynthesism-
mCORRECTmANSWERmWhichmofmthemfollowingmmetabolicmprocessesmismamcomponentmofmanabolicm
metabolism?
a.mProteinmsynthesis
b.mGlycolysis
c.mCitricmacidmcycle
d.mOxidativemphosphorylation
c.mThemsodium-potassiummpumpm-
mCORRECTmANSWERmWhichmofmthemfollowingmelectrochemicalmmechanismmismresponsiblemformma
intainingmcellmvolume?
a.mThemcalciummpump
b.mGlucosemtransporters
c.mThemsodium-potassiummpump
d.mATP-bindingmcassettem(ABC)mtransporters
d.mFailuremofmthemsodium-potassiummpumpm-mCORRECTmANSWERmCellularmhypoxiamresultsmin:
a.mEnhancedmATPmactivity
b.mLossmofmintracellularmcalcium
c.mIncreasedmpH
d.mFailuremofmthemsodium-potassiummpump
a.mAtrophymofmhermlegmmusclesm-
mCORRECTmANSWERmAm75myomwomanmdevelopsmweaknessminmhermlowermextremitiesmaftermamprol
ongedmperiodmofmbedmrest.mThismismmostmlikelymcausedmby:
a.mAtrophymofmhermlegmmuscles
UPDATE|EXAM
QUESTIONS WITH MULTIPLE
CHOICES |VERIFIED & REVISED
ANSWERS (NEW)!!!
a.mpositivemfeedbackm-
mCORRECTmANSWERmAnminitialmdisturbanceminmamsystemmsetsmoffmamchainmofmeventsmthatmdoesmno
tmfavormstabilitymandmoftenmabruptlymdisplacesmamsystemmfrommitsmsteadymstate:mwhatmismthat?
a.mPositivemFeedback
b.mNegativemFeedback
c.mDisease
d.mHomeostasis
b.mgumsm-mCORRECTmANSWERmWhatmorganmshrinksmwithmage?
a.mProstate
b.mGums
c.mHeart
d.mAllmofmthemabove
d.mtheremismlessmthirstmperceptionminmthemelderlym-
mCORRECTmANSWERmWhichmofmthemfollowingmismtrue?
a.mAnminfantmwillmhavemamslowermheartmratemthanmanmadult
b.mThemelderlymhavembettermtemperaturemsensations
c.mTheremaremmoremsweatmglandsminmanmelderlymperson
d.mTheremismlessmthirstmperceptionminmthemelderly
,c.mWomenmhavemamlowermhemoglobinmthanmmenm-
mCORRECTmANSWERmWhichmofmthemfollowingmismtrue?
a.mWomenmsnoremmoremthanmmen
b.mMenmhavemhighermcalciummlevels
c.mWomenmhavemamlowermhemoglobinmthanmmen
d.mMenmhavemamlowermcreatininemlevelmthanmwomen
b.mAcclimatizationm-
mCORRECTmANSWERmAnmincreaseminmnormalmadaptivemresponsemtomthemdecreasedmavailabilitymof
moxygenmatmhighmaltitudemismtermedmwhich?
a.mCircadian
b.mAcclimatization
c.mPopulation
d.mDiurnal
d.mIatrogenicm-
mCORRECTmANSWERmWhatmdoesmitmmeanmwhenmthemcausemofmthemdiseasemismunwantedmmedicalm
treatment?
a.mIdiopathic
b.mEcogenetic
c.mGenotypical
d.mIatrogenic
d.mNeonatalm-mCORRECTmANSWERmWhichmtermmismusedmformthemfirstmtwommonthsmofmlife?
a.mInfancy
b.mChildhood
c.mPrenatal
,d.mNeonatal
d.mSignm-mCORRECTmANSWERmWhichmismanmobjectivelymidentifiablemaberrationmofmthemdisease?
a.mSymptom
b.mSyndrome
c.mStage
d.mSign
c.mTheymincludemepinephrinemandmnorepinephrinem-
mCORRECTmANSWERmWhichmofmthemfollowingmismtruemregardingmcatecholamines?
a.mTheymaremfrommthemparasympatheticmnervousmsystem
b.mTheymcrossmthembloodmbrainmbarrier
c.mTheymincludemepinephrinemandmnorepinephrine
d.mTheymcausemofmdecreaseminmheartmrate
b.mEndorphinsmincreasemwithmstress,mresultingminmamdecreaseminmpainmperceptionm-
mCORRECTmANSWERmWhichmofmthemfollowingmismamtruemstatement?
a.mAntidiureticmhormonemismnotmimportantmformbloodmvolumemregulation
b.mEndorphinsmincreasemwithmstress,mresultingminmamdecreaseminmpainmperception
c.mEpinephrinemandmcortisolmactmverymdifferently
d.mCortisolmnegatesmepinephrine'smactivity
d.mTheymcrossmbymdiffusionm-
mCORRECTmANSWERmBymwhatmmechanismmdomlipidmmoleculesmcrossmcellmmembranes?
a.mTheymusemchannelmproteinsmasmammembranemtransportmsystem
b.mTheymaremtransportedmacrossmthemplasmammembranembymendocytosismandmexocytosis
c.mTheymusemvoltage-gatedmionmchannels
, d.mTheymcrossmbymdiffusion
a.mProteinmsynthesism-
mCORRECTmANSWERmWhichmofmthemfollowingmmetabolicmprocessesmismamcomponentmofmanabolicm
metabolism?
a.mProteinmsynthesis
b.mGlycolysis
c.mCitricmacidmcycle
d.mOxidativemphosphorylation
c.mThemsodium-potassiummpumpm-
mCORRECTmANSWERmWhichmofmthemfollowingmelectrochemicalmmechanismmismresponsiblemformma
intainingmcellmvolume?
a.mThemcalciummpump
b.mGlucosemtransporters
c.mThemsodium-potassiummpump
d.mATP-bindingmcassettem(ABC)mtransporters
d.mFailuremofmthemsodium-potassiummpumpm-mCORRECTmANSWERmCellularmhypoxiamresultsmin:
a.mEnhancedmATPmactivity
b.mLossmofmintracellularmcalcium
c.mIncreasedmpH
d.mFailuremofmthemsodium-potassiummpump
a.mAtrophymofmhermlegmmusclesm-
mCORRECTmANSWERmAm75myomwomanmdevelopsmweaknessminmhermlowermextremitiesmaftermamprol
ongedmperiodmofmbedmrest.mThismismmostmlikelymcausedmby:
a.mAtrophymofmhermlegmmuscles