Internal Medicine Rosh Boost Exam
is RA more common in men or women? women
what ages is RA most common? 40-50 years
RA morning stiffness lasting > 30 minutes
RA PE symmetrical soft, red, tender swelling in joints: MCP, PIP
-b/l ulnar deviation at MCP, boutinniere deformity and swan neck deformity
RA labs postive RF or anti-cyclic cirullinated peptide antibodies, inc ESR, inc CRP
RA most commonly caused by autoimmune destruction of synovial joints
RA tx DMARDs (methotrexate)
lung cancer rf hx of smoking, asbestos exposure
lung cancer symptoms cough, hemoptysis, dyspnea, cp, weight loss, back pain, neurologic symptoms
(CNS mets, paraneoplastic syndromes like Lambert-Eaton myasthenic syndrome)
pancoast tumor tumor in the superior sulcus, shoulder pain, horner syndrome
lung cancer labs hypercalcemia (PTHrP or bone mets), hyponatremia (SIADH), exudative effusion
lung cancer dx CXR, CT scan, bx
what is the most common form of lung cancer? non-small cell
types of non-small cell lung ca adenocarcinoma, squamous cell, large cell
tx of non-small cell lung cancers depends on staging, surg, chemo, or tyrosine kinase inhibitors if positive for
ALK or EGFR mutations
, Internal Medicine Rosh Boost Exam
what is small cell lung cancer associated with? neuroendocrine and paraneoplastic syndromes
tx of small cell lung cancer mets early, chemo, XRT, or whole brain radiation
what is the leading cause of cancer related death among lung ca
men and women?
lung cancer screening recs 50-80 yrs old with 20 pack year hx or who currently smoke or who have within the
last 15 years (low dose CT)
sepsis infxn that leads to systemic inflammation
SIRS criteria temp >38C (100.9) <36, WBC >12 <4, HR>90, RR>20 (consider infection, need 2/4)
what pathogen is the mcc of acute cystitis? e. coli
transudative pleural effusion causes Hydrostatic and osmotic factors - CCF, hepat and renal failure
exudative pleural effusion causes infection, malignancy, trauma
hypocalcemia signs Trousseau's sign
Chvostek's sign
how does vitamin d help increase calcium levels in the by facilitating gastrointestinal calcium absorption
body?
hypocalcemia sx seizures, parasthesia's
hypocalcemia labs Ca+ <8.5
hypocalcemia ekg prolonged QT interval
hypocalcemia tx Ca+ replacement orally for mild, Vitamin D for better Ca+ absorption
is RA more common in men or women? women
what ages is RA most common? 40-50 years
RA morning stiffness lasting > 30 minutes
RA PE symmetrical soft, red, tender swelling in joints: MCP, PIP
-b/l ulnar deviation at MCP, boutinniere deformity and swan neck deformity
RA labs postive RF or anti-cyclic cirullinated peptide antibodies, inc ESR, inc CRP
RA most commonly caused by autoimmune destruction of synovial joints
RA tx DMARDs (methotrexate)
lung cancer rf hx of smoking, asbestos exposure
lung cancer symptoms cough, hemoptysis, dyspnea, cp, weight loss, back pain, neurologic symptoms
(CNS mets, paraneoplastic syndromes like Lambert-Eaton myasthenic syndrome)
pancoast tumor tumor in the superior sulcus, shoulder pain, horner syndrome
lung cancer labs hypercalcemia (PTHrP or bone mets), hyponatremia (SIADH), exudative effusion
lung cancer dx CXR, CT scan, bx
what is the most common form of lung cancer? non-small cell
types of non-small cell lung ca adenocarcinoma, squamous cell, large cell
tx of non-small cell lung cancers depends on staging, surg, chemo, or tyrosine kinase inhibitors if positive for
ALK or EGFR mutations
, Internal Medicine Rosh Boost Exam
what is small cell lung cancer associated with? neuroendocrine and paraneoplastic syndromes
tx of small cell lung cancer mets early, chemo, XRT, or whole brain radiation
what is the leading cause of cancer related death among lung ca
men and women?
lung cancer screening recs 50-80 yrs old with 20 pack year hx or who currently smoke or who have within the
last 15 years (low dose CT)
sepsis infxn that leads to systemic inflammation
SIRS criteria temp >38C (100.9) <36, WBC >12 <4, HR>90, RR>20 (consider infection, need 2/4)
what pathogen is the mcc of acute cystitis? e. coli
transudative pleural effusion causes Hydrostatic and osmotic factors - CCF, hepat and renal failure
exudative pleural effusion causes infection, malignancy, trauma
hypocalcemia signs Trousseau's sign
Chvostek's sign
how does vitamin d help increase calcium levels in the by facilitating gastrointestinal calcium absorption
body?
hypocalcemia sx seizures, parasthesia's
hypocalcemia labs Ca+ <8.5
hypocalcemia ekg prolonged QT interval
hypocalcemia tx Ca+ replacement orally for mild, Vitamin D for better Ca+ absorption
