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ASCP BOC QLS CERTIFICATION – ORIGINAL PRACTICE EXAM
BANK: 150 VERIFIED QUESTIONS WITH DETAILED
LABORATORY SAFETY SOLUTIONS
Occupational Safety / Public Health Safety / Medical Laboratory Science
Exam Coverage :
✓ Management – Risk assessment, safety committees, SOPs,
OSHA terminology, emergency planning, regulatory
agencies
✓ General Safety – Ergonomics, fire safety, electrical safety,
compressed gases, PPE, dress code, spill response
✓ Chemical Safety – GHS, classifications, SDS, chemical
hygiene plans, storage, disposal, incompatibilities
✓ Biohazard Control – Bloodborne pathogens, biosafety
levels, OSHA Standard, exposure control plans, biosafety
cabinets
✓ Physical Environment – Waste management, emergency
preparedness, equipment safety, shipping,
decontamination
SECTION A: MANAGEMENT (Questions 1-30)
1. A laboratory safety officer is performing a risk
assessment. Which of the following represents the first step
in the risk assessment process?
A. Implementing controls to mitigate hazards
B. Identifying potential hazards in the workplace ✓
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C. Documenting all safety training sessions
D. Reviewing incident reports from the previous year
CORRECT: B
RATIONALE: The first step in risk assessment is hazard
identification. Controls are implemented after hazards are
identified and evaluated .
2. Under the OSHA General Duty Clause (Section 5(a)(1)),
employers are required to:
A. Provide personal protective equipment only upon employee
request
B. Provide a workplace free from recognized hazards ✓
C. Report all workplace injuries within 24 hours
D. Maintain a written safety program for all employees
CORRECT: B
RATIONALE: The General Duty Clause requires employers to
provide a workplace free from recognized hazards that could
cause death or serious harm, even when no specific OSHA
standard applies .
3. A laboratory's Exposure Control Plan (ECP) must be
reviewed and updated:
A. Every 5 years
B. Every 2 years
C. Annually ✓
D. Only when new equipment is purchased
CORRECT: C
RATIONALE: The ECP must be reviewed and updated annually
and be accessible to all employees to remain current with
changes in technology, procedures, and personnel .
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4. Which of the following is a required component of an
OSHA-compliant Exposure Control Plan?
A. Job classifications with occupational exposure only
B. Methods of compliance, including waste disposal
procedures only
C. Procedures for evaluating circumstances surrounding
exposure incidents only
D. All of the above ✓
CORRECT: D
RATIONALE: An OSHA-compliant ECP must identify job
classifications with occupational exposure, describe methods
of compliance including waste disposal procedures, and
include procedures for evaluating exposure incidents .
5. Which federal agency administers CLIA (Clinical
Laboratory Improvement Amendments) and sets quality
standards for laboratory testing on human specimens?
A. OSHA (Occupational Safety and Health Administration)
B. CMS (Centers for Medicare and Medicaid Services) ✓
C. CDC (Centers for Disease Control and Prevention)
D. EPA (Environmental Protection Agency)
CORRECT: B
RATIONALE: CMS administers CLIA (42 CFR Part 493), which
sets quality standards for laboratory testing on human
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specimens. OSHA enforces worker safety standards, CDC
provides guidelines, and EPA oversees hazardous waste .
6. Under OSHA's Bloodborne Pathogens Standard (29 CFR
1910.1030), the term "regulated waste" includes all of the
following EXCEPT:
A. Liquid or semi-liquid blood or other potentially infectious
material (OPIM)
B. Items that would release blood or OPIM if compressed
C. Items caked with dried blood that could release material
during handling
D. Uncontaminated packaging materials from specimen
collection kits ✓
CORRECT: D
RATIONALE: Regulated waste includes blood and OPIM, items
that would release blood if compressed, and items caked with
dried blood. Uncontaminated packaging materials are not
considered regulated waste .
7. Under the OSHA Hazard Communication Standard (29 CFR
1910.1200), employers must:
A. Only provide training when new employees are hired
B. Maintain a written hazard communication program ✓
C. Test all chemicals for toxicity before use
D. Provide safety data sheets only upon employee request
ASCP BOC QLS CERTIFICATION – ORIGINAL PRACTICE EXAM
BANK: 150 VERIFIED QUESTIONS WITH DETAILED
LABORATORY SAFETY SOLUTIONS
Occupational Safety / Public Health Safety / Medical Laboratory Science
Exam Coverage :
✓ Management – Risk assessment, safety committees, SOPs,
OSHA terminology, emergency planning, regulatory
agencies
✓ General Safety – Ergonomics, fire safety, electrical safety,
compressed gases, PPE, dress code, spill response
✓ Chemical Safety – GHS, classifications, SDS, chemical
hygiene plans, storage, disposal, incompatibilities
✓ Biohazard Control – Bloodborne pathogens, biosafety
levels, OSHA Standard, exposure control plans, biosafety
cabinets
✓ Physical Environment – Waste management, emergency
preparedness, equipment safety, shipping,
decontamination
SECTION A: MANAGEMENT (Questions 1-30)
1. A laboratory safety officer is performing a risk
assessment. Which of the following represents the first step
in the risk assessment process?
A. Implementing controls to mitigate hazards
B. Identifying potential hazards in the workplace ✓
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C. Documenting all safety training sessions
D. Reviewing incident reports from the previous year
CORRECT: B
RATIONALE: The first step in risk assessment is hazard
identification. Controls are implemented after hazards are
identified and evaluated .
2. Under the OSHA General Duty Clause (Section 5(a)(1)),
employers are required to:
A. Provide personal protective equipment only upon employee
request
B. Provide a workplace free from recognized hazards ✓
C. Report all workplace injuries within 24 hours
D. Maintain a written safety program for all employees
CORRECT: B
RATIONALE: The General Duty Clause requires employers to
provide a workplace free from recognized hazards that could
cause death or serious harm, even when no specific OSHA
standard applies .
3. A laboratory's Exposure Control Plan (ECP) must be
reviewed and updated:
A. Every 5 years
B. Every 2 years
C. Annually ✓
D. Only when new equipment is purchased
CORRECT: C
RATIONALE: The ECP must be reviewed and updated annually
and be accessible to all employees to remain current with
changes in technology, procedures, and personnel .
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4. Which of the following is a required component of an
OSHA-compliant Exposure Control Plan?
A. Job classifications with occupational exposure only
B. Methods of compliance, including waste disposal
procedures only
C. Procedures for evaluating circumstances surrounding
exposure incidents only
D. All of the above ✓
CORRECT: D
RATIONALE: An OSHA-compliant ECP must identify job
classifications with occupational exposure, describe methods
of compliance including waste disposal procedures, and
include procedures for evaluating exposure incidents .
5. Which federal agency administers CLIA (Clinical
Laboratory Improvement Amendments) and sets quality
standards for laboratory testing on human specimens?
A. OSHA (Occupational Safety and Health Administration)
B. CMS (Centers for Medicare and Medicaid Services) ✓
C. CDC (Centers for Disease Control and Prevention)
D. EPA (Environmental Protection Agency)
CORRECT: B
RATIONALE: CMS administers CLIA (42 CFR Part 493), which
sets quality standards for laboratory testing on human
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specimens. OSHA enforces worker safety standards, CDC
provides guidelines, and EPA oversees hazardous waste .
6. Under OSHA's Bloodborne Pathogens Standard (29 CFR
1910.1030), the term "regulated waste" includes all of the
following EXCEPT:
A. Liquid or semi-liquid blood or other potentially infectious
material (OPIM)
B. Items that would release blood or OPIM if compressed
C. Items caked with dried blood that could release material
during handling
D. Uncontaminated packaging materials from specimen
collection kits ✓
CORRECT: D
RATIONALE: Regulated waste includes blood and OPIM, items
that would release blood if compressed, and items caked with
dried blood. Uncontaminated packaging materials are not
considered regulated waste .
7. Under the OSHA Hazard Communication Standard (29 CFR
1910.1200), employers must:
A. Only provide training when new employees are hired
B. Maintain a written hazard communication program ✓
C. Test all chemicals for toxicity before use
D. Provide safety data sheets only upon employee request
