Dama Dmbok Sample View Ahead Exam Questions Full Solution Guide.pdf

DAMA DMBOK SAMPLE VIEW AHEAD EXAM QUESTIONS FULL SOLUTION GUIDE




Question:
Correlation.

Answer:
Two variables occur together but causation is not proven



Question:
Causation.

Answer:
One factor directly causes another



Question:
Complementation control.

Answer:
Reintroducing a gene to confirm that gene deletion caused the phenotype



Question:
Competition control.

Answer:
Using excess unlabeled substrate to test binding specificity



Question:
EMSA.

,Answer:
Electrophoretic Mobility Shift Assay used to detect protein-DNA interactions



Question:
EMSA shift.

Answer:
Slower migration of DNA on a gel indicating protein binding



Question:
Specific binding.

Answer:
Binding that occurs only with the correct DNA or ligand



Question:
Competition assay.

Answer:
Adding excess unlabeled DNA to test specificity of binding



Question:
RpoN.

Answer:
Sigma factor that activates transcription of rpoS



Question:
RpoS.

Answer:

, Alternative sigma factor regulating virulence genes



Question:
OspC.

Answer:
Outer surface protein required for early infection by Lyme bacteria



Question:
RpoN-RpoS-OspC axis.

Answer:
Regulatory cascade controlling virulence gene expression



Question:
Virulence factor.

Answer:
Molecule that enables a pathogen to infect or damage a host



Question:
Observation about OspC.

Answer:
OspC expression increases when bacteria move from tick to mammal



Question:
Hypothesis about OspC.

Answer:
OspC is required for mammalian infection