NBME HISTOLOGY PRACTICE EXAM: 200
VERIFIED Q&A WITH RATIONALES – LATEST
2026/2027 UPDATE – PASS WITH CONFIDENCE!
Histology NBME Practice Exam – Questions
and ☑VERIFIED ANSWERs
Section 1: Cell Biology & Nuclear Structure
Question 1
Nuclear pores:
A) Combine to form a hexagonal structure
B) Have 50nm in diameter
C) Their number is not connected with cellular
activity
D) Nuclear lamina are connected to their inner
rings
E) A and C are correct
F) B and D are correct
,Correct ☑VERIFIED ANSWER: E) A and C are
correct
Rationale: Nuclear pores form a hexagonal
(octagonal) symmetry structure and their
number varies with cellular activity—highly
active cells have more pores. They are
approximately 120nm in total diameter with a
40nm central channel, not 50nm. The nuclear
lamina connects to the inner nuclear
membrane, not directly to pore inner rings.
Question 2
The plasma membrane consists of the
following elements except:
A) Transmembrane proteins
B) Peripheral proteins
C) Cholesterol
,D) Microfibers
E) A and C are correct
F) B and D are correct
Correct ☑VERIFIED ANSWER: D) Microfibers
Rationale: The plasma membrane is composed
of a phospholipid bilayer with transmembrane
proteins, peripheral proteins, cholesterol, and
carbohydrates. Microfibers (microfilaments) are
cytoskeletal components found beneath the
membrane, not structural elements of the
membrane itself.
Question 3
The glycocalyx can be defined as:
A) The masses of extracellular matrix
B) Basement membrane rich in collagen
C) Layer made of carbohydrate chains linked
, D) A thin sheath of actin filaments located
beneath the cell membrane
E) A and C are correct
F) B and D are correct
Correct ☑VERIFIED ANSWER: C) Layer made of
carbohydrate chains linked
Rationale: The glycocalyx is a carbohydrate-rich
layer on the cell surface consisting of
glycoproteins and glycolipids. It functions in cell
recognition, adhesion, and protection. It is not
extracellular matrix, basement membrane, or
actin-based.
Question 4
A process by which liquid droplets are ingested
by living cells is:
VERIFIED Q&A WITH RATIONALES – LATEST
2026/2027 UPDATE – PASS WITH CONFIDENCE!
Histology NBME Practice Exam – Questions
and ☑VERIFIED ANSWERs
Section 1: Cell Biology & Nuclear Structure
Question 1
Nuclear pores:
A) Combine to form a hexagonal structure
B) Have 50nm in diameter
C) Their number is not connected with cellular
activity
D) Nuclear lamina are connected to their inner
rings
E) A and C are correct
F) B and D are correct
,Correct ☑VERIFIED ANSWER: E) A and C are
correct
Rationale: Nuclear pores form a hexagonal
(octagonal) symmetry structure and their
number varies with cellular activity—highly
active cells have more pores. They are
approximately 120nm in total diameter with a
40nm central channel, not 50nm. The nuclear
lamina connects to the inner nuclear
membrane, not directly to pore inner rings.
Question 2
The plasma membrane consists of the
following elements except:
A) Transmembrane proteins
B) Peripheral proteins
C) Cholesterol
,D) Microfibers
E) A and C are correct
F) B and D are correct
Correct ☑VERIFIED ANSWER: D) Microfibers
Rationale: The plasma membrane is composed
of a phospholipid bilayer with transmembrane
proteins, peripheral proteins, cholesterol, and
carbohydrates. Microfibers (microfilaments) are
cytoskeletal components found beneath the
membrane, not structural elements of the
membrane itself.
Question 3
The glycocalyx can be defined as:
A) The masses of extracellular matrix
B) Basement membrane rich in collagen
C) Layer made of carbohydrate chains linked
, D) A thin sheath of actin filaments located
beneath the cell membrane
E) A and C are correct
F) B and D are correct
Correct ☑VERIFIED ANSWER: C) Layer made of
carbohydrate chains linked
Rationale: The glycocalyx is a carbohydrate-rich
layer on the cell surface consisting of
glycoproteins and glycolipids. It functions in cell
recognition, adhesion, and protection. It is not
extracellular matrix, basement membrane, or
actin-based.
Question 4
A process by which liquid droplets are ingested
by living cells is:
